Medicinal Chemistry in the Frølund Group
We are aiming for
We are focusing on ligand gated ion channels (LGIC) with a particular interest in GABAA and nicotinic ACh receptors, but our projects also involve GABA transporters and GHB pharmacology. We do structure-activity studies aiming for receptor subtype selectivity and pharmacological tools/biomarkers, for studying ligand-receptor interactions and dynamics.We have been successful in developing fundamental compounds e.g. highly potent agonists and antagonists, some of these selective for specific receptor subtypes.
All projects are interdisciplinary, building on international and national collaborations. With a platform in medicinal chemistry, our projects bridges with molecular pharmacology, computational and biostructural chemistry.
Group members
| Name | Title | Phone | |
|---|---|---|---|
| Annalisa Invernizzi | Erasmus master student | ||
| Arien Chen | Erasmus master student | ||
| Elena Martino | Bachelor student | ||
| Francesco Bavo | Postdoc | +45 353-27264 | |
| Frederik Badsberg Samuelsen | Bachelor student | ||
| Ida Aaberg Lillethorup | Master thesis student | ||
| Jonas Odgaard Petersen | Enrolled PhD student | ||
| Katrin Daraj | Master thesis student | +45 42 79 17 20 | |
| Kirsten Braad Iskov | Laboratory technician | +45 51 33 12 49 | |
| Lasse Brokmose Poulsen | Master thesis student | ||
| Ludovica Stella Sirocchi | PhD fellow | +45 353-36384 | |
| Mohamed A. Shehata | Postdoc | +45 50 25 56 40 | |
| Nicoline Ninn Jensen | |||
| Yongsong Tian | PhD Fellow | +45 50 30 07 91 |