Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries
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Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries. / Edvinsson, L; Ahnstedt, H; Larsen, R; Sheykhzade, Majid.
In: Acta Physiologica (Print), Vol. 210, No. 4, 04.2014, p. 811-22.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries
AU - Edvinsson, L
AU - Ahnstedt, H
AU - Larsen, R
AU - Sheykhzade, Majid
N1 - © 2014 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd.
PY - 2014/4
Y1 - 2014/4
N2 - Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.
AB - Calcitonin gene-related peptide (CGRP) and its receptor are widely distributed within the circulation and the mechanism behind its vasodilation not only differs from one animal species to another but is also dependent on the type and size of vessel. The present study examines the nature of CGRP-induced vasodilation, characteristics of the CGRP receptor antagonist telcagepant and localization of the key components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) of the CGRP receptor in human subcutaneous arteries.
U2 - 10.1111/apha.12213
DO - 10.1111/apha.12213
M3 - Journal article
C2 - 24330354
VL - 210
SP - 811
EP - 822
JO - Acta Physiologica
JF - Acta Physiologica
SN - 1748-1708
IS - 4
ER -
ID: 106213297