Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion. / Skovsted, Gry Freja; Kruse, L.S.; Larsen, R; Pedersen, A F; Trautner, S; Sheykhzade, Majid; Edvinsson, L.

In: British Journal of Pharmacology, Vol. 171, No. 11, 28.01.2014, p. 2726-2738.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Skovsted, GF, Kruse, LS, Larsen, R, Pedersen, AF, Trautner, S, Sheykhzade, M & Edvinsson, L 2014, 'Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion', British Journal of Pharmacology, vol. 171, no. 11, pp. 2726-2738. https://doi.org/10.1111/bph.12606

APA

Skovsted, G. F., Kruse, L. S., Larsen, R., Pedersen, A. F., Trautner, S., Sheykhzade, M., & Edvinsson, L. (2014). Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion. British Journal of Pharmacology, 171(11), 2726-2738. https://doi.org/10.1111/bph.12606

Vancouver

Skovsted GF, Kruse LS, Larsen R, Pedersen AF, Trautner S, Sheykhzade M et al. Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion. British Journal of Pharmacology. 2014 Jan 28;171(11):2726-2738. https://doi.org/10.1111/bph.12606

Author

Skovsted, Gry Freja ; Kruse, L.S. ; Larsen, R ; Pedersen, A F ; Trautner, S ; Sheykhzade, Majid ; Edvinsson, L. / Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion. In: British Journal of Pharmacology. 2014 ; Vol. 171, No. 11. pp. 2726-2738.

Bibtex

@article{9517a8fd89ff4ddbba09d0b73b0d1f50,
title = "Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion",
abstract = "Endothelins act via two receptor subtypes, endothelin receptor type A (ETA ) and type B (ETB ). Under physiological conditions in coronary arteries ETA receptors expressed in smooth muscle cells mediate vasoconstriction whereas ETB receptors mainly found in endothelial cells mediate vasorelaxation. However, under pathophysiological conditions ETB receptors may also be expressed in vascular smooth muscle cells mediating vasoconstriction. We aimed to investigate whether vasoconstrictor ETB receptors are upregulated in coronary arteries after experimental myocardial ischemia in rats.",
author = "Skovsted, {Gry Freja} and L.S. Kruse and R Larsen and Pedersen, {A F} and S Trautner and Majid Sheykhzade and L Edvinsson",
note = "This article is protected by copyright. All rights reserved.",
year = "2014",
month = jan,
day = "28",
doi = "10.1111/bph.12606",
language = "English",
volume = "171",
pages = "2726--2738",
journal = "British Journal of Pharmacology",
issn = "0007-1188",
publisher = "Wiley",
number = "11",

}

RIS

TY - JOUR

T1 - Heart ischemia-reperfusion induces local upregulation of vasoconstrictor endothelin receptor type B in rat coronary arteries downstream of occlusion

AU - Skovsted, Gry Freja

AU - Kruse, L.S.

AU - Larsen, R

AU - Pedersen, A F

AU - Trautner, S

AU - Sheykhzade, Majid

AU - Edvinsson, L

N1 - This article is protected by copyright. All rights reserved.

PY - 2014/1/28

Y1 - 2014/1/28

N2 - Endothelins act via two receptor subtypes, endothelin receptor type A (ETA ) and type B (ETB ). Under physiological conditions in coronary arteries ETA receptors expressed in smooth muscle cells mediate vasoconstriction whereas ETB receptors mainly found in endothelial cells mediate vasorelaxation. However, under pathophysiological conditions ETB receptors may also be expressed in vascular smooth muscle cells mediating vasoconstriction. We aimed to investigate whether vasoconstrictor ETB receptors are upregulated in coronary arteries after experimental myocardial ischemia in rats.

AB - Endothelins act via two receptor subtypes, endothelin receptor type A (ETA ) and type B (ETB ). Under physiological conditions in coronary arteries ETA receptors expressed in smooth muscle cells mediate vasoconstriction whereas ETB receptors mainly found in endothelial cells mediate vasorelaxation. However, under pathophysiological conditions ETB receptors may also be expressed in vascular smooth muscle cells mediating vasoconstriction. We aimed to investigate whether vasoconstrictor ETB receptors are upregulated in coronary arteries after experimental myocardial ischemia in rats.

U2 - 10.1111/bph.12606

DO - 10.1111/bph.12606

M3 - Journal article

C2 - 24467585

VL - 171

SP - 2726

EP - 2738

JO - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 0007-1188

IS - 11

ER -

ID: 98988340