Trond Ulven
Professor
- 2016
A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Due-Hansen, M. E., Pandey, S. K., Ulven, Elisabeth Rexen, Andersen, R., Hansen, S. V. F. & Ulven, Trond, 2016, In: Organic & Biomolecular Chemistry. 14, 2, p. 430-433 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Controlled generation and use of CO in flow
Hansen, S. V. F., Wilson, Z. E., Ulven, Trond & Ley, S. V., 2016, In: Reaction Chemistry & Engineering. 1, 3, p. 280-287 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer
Ulven, Elisabeth Rexen, Hudson, B. D., Hansen, A. H., Milligan, G. & Ulven, Trond, 2016, In: Journal of Medicinal Chemistry. 59, 10, p. 4849-4858 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein-Coupled Receptor 120
Prihandoko, R., Alvarez-Curto, E., Hudson, B. D., Butcher, A. J., Ulven, Trond, Miller, A. M., Tobin, A. B. & Milligan, G., 2016, In: Molecular Pharmacology. 89, 5, p. 505-520 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity
Goncalves de Azavedo, C. M. B. P., Watterson, K. R., Wargent, E. T., Hansen, S. V. F., Hudson, B. D., Kępczyńska, M. A., Dunlop, J., Shimpukade, B., Ulven, Elisabeth Rexen, Milligan, G., Stocker, C. J. & Ulven, Trond, 2016, In: Journal of Medicinal Chemistry. 59, 19, p. 8868-8878 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands
Sergeev, E., Hojgaard Hansen, A., Pandey, S. K., Mackenzie, A. E., Hudson, B. D., Ulven, Trond & Milligan, G., 2016, In: Journal of Biological Chemistry. 291, p. 303-317 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment
Björkman, L., Mårtensson, J., Winther, M., Gabl, M., Holdfeldt, A., Uhrbom, M., Bylund, J., Højgaard Hansen, A., Pandey, S. K., Ulven, Trond, Forsman, H. & Dahlgren, C., 2016, In: Molecular and Cellular Biology. 36, 20, p. 2583-2595 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice
Gozal, D., Qiao, Z., Almendros, I., Zheng, J., Khalyfa, A., Shimpukade, B. & Ulven, Trond, 2016, In: International Journal of Obesity. 40, 7, p. 1143-1149 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area and Robust in Vivo Efficacy
Hansen, S. V. F., Ulven, Elisabeth Rexen, Urban, C., Hudson, B. D., Stocker, C. J., Due-Hansen, M. E., Wargent, E. T., Shimpukade, B., Almeida, R., Ejsing, C. S., Cawthorne, M. A., Kassack, M. U., Milligan, G. & Ulven, Trond, 1 Mar 2016, In: Journal of Medicinal Chemistry. 59, 6, p. 2841-2846 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor
Grundmann, M., Tikhonova, I. G., Hudson, B. D., Smith, N. J., Mohr, K., Ulven, Trond, Milligan, G., Kenakin, T. & Kostenis, E., 17 Mar 2016, In: Cell Chemical Biology. 23, 3, p. 392-403 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)
Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias
Sergeev, E., Hansen, A. H., Bolognini, D., Kawakami, K., Kishi, T., Aoki, J., Ulven, Trond, Inoue, A., Hudson, B. D. & Milligan, G., 2017, In: Scientific Reports. 7, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Development and Characterization of a Fluorescent Tracer for the Free Fatty Acid Receptor 2 (FFA2/GPR43)
Hansen, A. H., Sergeev, E., Pandey, S. K., Hudson, B. D., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2017, In: Journal of Medicinal Chemistry. 60, 13, p. 5638-5645 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Houthuijzen, J. M., Oosterom, I., Hudson, B. D., Hirasawa, A., Daenen, L. G. M., McLean, C. M., Hansen, S. V. F., van Jaarsveld, M. T. M., Peeper, D. S., Jafari Sadatmand, S., Roodhart, J. M. L., van de Lest, C. H. A., Ulven, Trond, Ishihara, K., Milligan, G. & Voest, E., 2017, In: F A S E B Journal. 31, 5, p. 2195-2209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Pharmacological Tool Compounds for the Free Fatty Acid Receptor 4 (FFA4/GPR120)
Hansen, S. V. F. & Ulven, Trond, 2017, Free Fatty Acid Receptors. Springer Science+Business Media, p. 33-56 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation
Dragano, N. R. V., Solon, C., Ramalho, A. F., de Moura, R. F., Razolli, D. S., Ulven, Elisabeth Rexen, Goncalves de Azavedo, C. M. B. P., Ulven, Trond & Velloso, L. A., 2017, In: Journal of Neuroinflammation. 14, 91, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4
Watterson, K. R., Hansen, S. V. F., Hudson, B. D., Alvarez-Curto, E., Raihan, S. Z., Goncalves de Azavedo, C. M. B. P., Martin, G., Dunlop, J., Yarwood, S. J., Ulven, Trond & Milligan, G., 2017, In: Molecular Pharmacology. 91, 6, p. 630-641 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Succinct synthesis of saturated hydroxy fatty acids and
Kaspersen, M. H., Jenkins, L., Dunlop, J., Milligan, G. & Ulven, Trond, 2017, In: MedChemComm. 8, 6, p. 1360-1365 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84
Mahmud, Z. A., Jenkins, L., Ulven, Trond, Labéguère, F., Gosmini, R., De Vos, S., Hudson, B. D., Tikhonova, I. G. & Milligan, G., 2017, In: Scientific Reports. 7, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Complex Pharmacology of Free Fatty Acid Receptors
Milligan, G., Shimpukade, B., Ulven, Trond & Hudson, B. D., 11 Jan 2017, In: Chemical Reviews. 117, 1, p. 67-110 44 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Hansen, A. H., Sergeev, E., Bolognini, D., Sprenger, R. R., Ekberg, J. H., Ejsing, C. S., McKenzie, C. J., Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2018, In: Journal of Medicinal Chemistry. 61, 21, p. 9534-9550 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat
Schilperoort, M., van Dam, A. D., Hoeke, G., Shabalina, I. G., Okolo, A., Hanyaloglu, A. C., Dib, L. H., Mol, I. M., Caengprasath, N., Chan, Y., Damak, S., Miller, A. R., Coskun, T., Shimpukade, B., Ulven, Trond, Kooijman, S., Rensen, P. C. & Christian, M., 17 Jan 2018, In: E M B O Molecular Medicine. 10, 3, 18 p., e8047.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum
Domljanovic, I., Ulven, Elisabeth Rexen, Ulven, Trond, Thomsen, R. P., Okholm, A. H., Kjems, J., Voss, A., Taskova, M. & Astakhova, K., 31 Jul 2018, In: ACS Omega. 3, 7, p. 7580-7586 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of tetrahydroisoquinoline and tetrahydrobenzoazepine derivatives for use as GPR120 modulators.
Brown, J., Connolly, S., Hansen, S. V. F., Milne, G., Shimpukade, B., Smyth, D., Thomas, G., Ulven, Trond, Brvar, M. & Rigby, A., 27 Sep 2018, Caldan Therapeutics Limited, UK ., Patent No. WO2018172727A1Research output: Patent
- 2019
- Published
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
Theiler, A., Bärnthaler, T., Platzer, W., Richtig, G., Peinhaupt, M., Rittchen, S., Kargl, J., Ulven, Trond, Marsh, L. M., Marsche, G., Schuligoi, R., Sturm, E. M. & Heinemann, A., 2019, In: The Journal of allergy and clinical immunology. 144, 3, p. 764-776Research output: Contribution to journal › Journal article › Research › peer-review
ID: 187375453
Most downloads
-
282
downloads
Discovery of a Potent Thiazolidine Free Fatty Acid Receptor 2 Agonist with Favorable Pharmacokinetic Properties
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
111
downloads
Dihydropyridine Fluorophores Allow for Specific Detection of Human Antibodies in Serum
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
110
downloads
Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival
Research output: Contribution to journal › Journal article › Research › peer-review
Published