Paul Robert Hansen

Paul Robert Hansen

Associate Professor


  1. Published

    N-Derivatized Analogues of Indolicidin and [Phe4,6,8,9,11] Indolicidin with Enhanced Antibacterial Activity

    Neerup, T. S. R. & Hansen, Paul Robert, 2004.

    Research output: Contribution to conferencePosterResearch

  2. Published

    N-terminal derivatized analogues of indolicidin and [Phe4,6,8,9,11]indolicidin with enhanced antibacterial activity

    Ryge, T. S. & Hansen, Paul Robert, 2004. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  3. Published

    Sinapis phylogeny and evolution of glucosinolates and specific nitrile degrading enzymes

    Agerbirk, Niels, Warwick, S. I., Hansen, Paul Robert & Olsen, C. E., 2008, In: Phytochemistry. 69, 17, p. 2937-2949 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    C-locked analogs of the antimicrobial peptide BP214

    Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabelling agents of PEPHC1 for PET imaging of EGFRvIII

    Hansen, C. L., Kuhnast, B., Hinnen, F., Gillings, N., Hansen, Paul Robert, Kjær, A. & Dolle, F., 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  6. Published

    A Biophysical Study of the Interactions between the Antimicrobial Peptide Indolicidin and Lipid Model Systems

    Nielsen, J. E., Lind, T. K., Lone, A., Gerelli, Y., Hansen, Paul Robert, Jenssen, H., Cárdenas, M. & Lund, R., 2019, In: B B A - Biomembranes. 1861, 7, p. 1355-1364

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published

    A Minimal Labor Approach to Identifying the Optimal Anoplin Analog using ANOVA.

    Munk, J., Ritz, C., Petrine Fliedner, F., Frimodt-Møller, N. & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  9. Published

    A Novel Peptide-Peptoid Hybrid Active Against MRSP Skin Infections

    Greco, I., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 4 Nov 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  10. Published

    A combinatorial approach to identify novel peptide targeted against the cancer specific receptor mutation, EFGRvIII.

    Denholdt, C., Hansen, Paul Robert, Pedersen, N., Skovgaard Poulsen, H., Gillings, N. & Kjær, A., 2009.

    Research output: Contribution to conferencePosterResearch

  11. Published

    A quantitative assay to measure the interaction between immunogenic peptides and purified class I major histocompatibility complex molecules

    Olsen, A. C., Pedersen, L. O., Hansen, A. S., Buus, Søren, Nissen, Mogens Holst, Olsen, M., Hansen, Paul Robert & Holm, A., 1994, In: European Journal of Immunology. 24, 2, p. 385-92 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A ¤new method for the synthesis of neoglycopeptides

    Hansen, Paul Robert, Olsen, C. E. & Holm, A., 1998, In: Bioconjugate Chemistry. 9, 1, p. 126-131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A ¤new strategy for the synthesis of neoglycopeptides based on maleimido-thiol chemistry

    Hansen, Paul Robert, Heron, I., Olsen, C. E., Jakobsen, M. H. & Holm, A., 1998, Ikke angivet. Ramage, R. & Epton, R. (eds.). Mayflower Scientific, p. 457-458 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  14. Published
  15. Published

    Advances in development of antimicrobial peptidomimetics as potential drugs

    Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 28 Aug 2017, In: Molecules. 22, 9, 60 p., 1430.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Ala-scan study of the antibacterial peptide anoplin

    Ifrah, D., Neerup, T. S. R. & Hansen, Paul Robert, 1 Sep 2004.

    Research output: Contribution to conferencePosterResearch

  17. Published

    Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

    Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Amphibian antimicrobial peptide fallaxin analogue FL9 affects virulence gene expression and DNA replication in Staphylococcus aureus

    Gottschalk, S., Gottlieb, C. T., Vestergaard, M., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 1 Dec 2015, In: Journal of Medical Microbiology. 64, 12, p. 1504-1513 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An ANOVA-based model to identify the optimal antimicrobial peptide in a combination matrix

    Munk, J. K., Ritz, C., Fliedner, F. P., Frimodt-Moller, N. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  20. Published

    An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Analogues of a Cyclic Antimicrobial Peptide with a Flexible Linker Show Promising Activity Against Pseudomonas aeruginosa and Staphylococcus aureus

    Thomsen, T. T., Mendel, H. C., Al-Mansour, W., Oddo, A., Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: Antibiotics. 9, 7, 13 p., 366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Analogues of the antibacterial peptide RRWWRF-NH2

    Hansen, Paul Robert, Neerup, T. S. R. & Ifrah, D., 2004.

    Research output: Contribution to conferencePosterResearch

  23. Published

    Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice

    Metts, M. S., McDowell, J. V., Theisen, Michael, Hansen, Paul Robert & Marconi, R. T., 1 Jun 2003, In: Infection and Immunity. 71, 6, p. 3587-3596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Analysis of the OspE determinants involved in the binding of factor H and OspE targeting antibodies elicited during infection in mice

    Metts, M. S., McDowell, J. V., Theisen, M., Hansen, Paul Robert & Marconi, R. T., 2003, In: Infection and Immunity. 71, p. 3587-3596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Antibacterial activity of a human lysozyme C-terminal fragment conjugated to lipophilic acids

    Ifrah, D. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  26. Published

    Antibacterial activity of a human lysozyme C-terminal fragment conjugated to lipophilic acids

    Ifrah, D. & Hansen, Paul Robert, 2004. 3 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  27. Published

    Antibacterial lysine-peptoid hybrids with selective cytolytic activity

    Neerup, T. S. R. & Hansen, Paul Robert, 2005.

    Research output: Contribution to conferencePosterResearch

  28. Published

    Antibodies to calnexin and mutated calreticulin are common in human sera

    Kyllesbech, C., Trier, N. H., Mughal, F. P., Hansen, Paul Robert, Holmström, M. O., Fassi, Daniel El , Hasselbalch, H., Skov, V., Kjær, L., Andersen, Mads Hald, Ciplys, E., Slibinskas, R., Fredriksen, Jette Lautrup, Højrup, P. & Houen, G., 2023, In: Current Research in Translational Medicine. 71, 2, 103380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Antibodies with specificity for native and denatured forms of ovalbumin differ in reactivity between enzyme-linked immunosorbent assays.

    Holm, B. E., Bergmann, A. C., Hansen, Paul Robert, Koch, C., Houen, G. & Trier, N. H., 1 Feb 2015, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 123, 2, p. 136–145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Antigenic profiling of a Chlamydia trachomatis gene-expression library

    Folmann, F., Olsen, A. W., Jensen, K. T., Hansen, Paul Robert, Andersen, P. & Theisen, M., 2008, In: Journal of Infectious Diseases. 197, p. 897-905 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

    Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Antimicrobial activities of synthetic anoplin analogues against methicillin-resistant Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus faecium and Candida albicans

    Munk, J. K., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Moller, N., Nyberg, N., Wimmer, R. & Hansen, Paul Robert, 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  33. Published

    Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi

    Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008, In: Chemotherapy. 54, 2, p. 152-156 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Antimicrobial activity of small 3-(2 naphthyl)-L-alanine containing peptides

    Hansen, Paul Robert & Frimodt-Møller, N., 2010, In: Proceedings of the 31st European Peptide Symposium,. 2 p.

    Research output: Contribution to journalConference articleResearch

  35. Published

    Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

    Primo, L. M. D. G., Roque-Borda, C. A., Carnero Canales, C. S., Caruso, I. P., de Lourenço, I. O., Colturato, V. M. M., Sábio, R. M., de Melo, F. A., Vicente, E. F., Chorilli, M., da Silva Barud, H., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2024, In: Carbohydrate Polymers. 323, 17 p., 121449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Antimikrobielle peptider: et nyt våben mod multiresistente bakterier

    Munk, J., Hansen, Paul Robert & Franzyk, Henrik, 2012, In: Lægemiddelforskning. 2012, p. 9-11

    Research output: Contribution to journalJournal articleCommunication

  37. Published

    Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

    Kłodzińska, S. N., Molchanova, N., Franzyk, Henrik, Hansen, Paul Robert, Damborg, Peter Panduro & Nielsen, Hanne Mørck, Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Broadening CD4(+) and CD8(+) T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

    Filskov, J., Mikkelsen, M., Hansen, Paul Robert, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Andersen, P., Bukh, Jens & Agger, E., Jul 2017, In: Journal of Virology. 91, 14, 18 p., e00130-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Characterization of synthetic peptides by mass spectrometry

    Prabhala, B. K., Mirza, Osman Asghar, Højrup, P. & Hansen, Paul Robert, 2015, Methods in Molecular Biology: Peptide Antibiodies. Springer, p. 77-82

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  40. Published

    Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections

    Greco, I., Emborg, A., Jana, B., Molchanova, N., Oddo, A., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Scientific Reports. 9, 12 p., 3679.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Chemical Synthesis of Antimicrobial Peptides.

    Münzker, L., Oddo, A. & Hansen, Paul Robert, 2017, Chemical Synthesis of Antimicrobial Peptides: Münzker L, Oddo A, Hansen PR. Methods Mol Biol. 2017; . Hansen, P. R. (ed.). Springer, Vol. 1548. p. 35-49.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. Published

    Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabeling agents of PEPHC1 for PET imaging of EGFRvIII

    Hansen, C. L., Kuhnast, B., Hinnen, F., Dollé, F., Gillings, N., Hansen, Paul Robert & Kjær, Andreas, 2009, In: Advances in Experimental Medicine and Biology. 611, p. 405-6 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Complex metabolism of aromatic glucosinolates in Pieris rapae caterpillars involving nitrile formation, hydroxylation, demethylation, sulfation, and host plant dependent carboxylic acid formation

    Agerbirk, Niels, Olsen, C. E., Poulsen, E., Jacobsen, Niels & Hansen, Paul Robert, 2010, In: Insect Biochemistry and Molecular Biology. 40, 2, p. 126-137 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

    Trier, N. H., Dam, C., Olsen, D., Hansen, Paul Robert & Houen, G., 2015, In: P L o S One. p. 1-12 12 p., 0144707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

    Welner, S., Trier, N. H., Morten Frisch, M., Locht, H., Hansen, Paul Robert & Houen, G., 2013, In: Molecular Cancer. 12, 1, 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides

    Greco, I., Molchanova, N., Holmedal, E., Jenssen, H., Hummel, B. D., Watts, J. L., Håkansson, J., Hansen, Paul Robert & Svenson, J., 2020, In: Scientific Reports. 10, 13 p., 13206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Cross-reactivity of a human IgG1 anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

    Trier, N. H., Leth, M. L., Hansen, Paul Robert & Houen, G., 31 Dec 2012, In: Protein Science. 21, 12, p. 1929-1941

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

    Lone, A. B. N., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 2022, In: European Journal of Medicinal Chemistry Reports. 6, 7 p., 100080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus

    Kjelstrup, S., Hansen, P. M. P., Thomsen, Line Elnif, Hansen, Paul Robert & Løbner-Olesen, Anders, 2013, In: P L o S One. 8, 9, 13 p., e72273.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Cytotoxicity and in vivo efficacy of a novel antimicrobial peptoid against Staphylococcus pseudintermedius

    Damborg, Peter Panduro, Skindersø, M. E., Hansen, Paul Robert, Bahnsen, J. S., Nielsen, Hanne Mørck & Guardabassi, Luca, Aug 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

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