Søren Brøgger Christensen
Professor emeritus, Professor, emeritus
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1-β-vicianosyl-(S)-2-methylbutyrate, a 1-O-acylglycoside from Acacia sieberana var. Woodii
Christensen, Søren Brøgger, Brimer, L. & Nartey, F., 1982, In: Phytochemistry. 21, 11, p. 2683-2685 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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19a-hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum
Traore, M., Ziegler, H. L., Olsen, C. E., Hassanata, M., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2009, In: Natural Product Research. 23, 12, p. 1108-1111 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2-β-d-Glucopyranosyloxy-2-methylpropanol in Acacia sieberana var. woodii
Brimer, L., Christensen, Søren Brøgger & Nartey, F., 1982, In: Phytochemistry. 21, 8, p. 2005-2007 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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6-O-Methylkrigeine, a new Amaryllidaceae alkaloid from Nerine huttoniae Schönland
Molander, M., Christensen, Søren Brøgger, Jaeger, A. K., Olsen, C. E. & Rønsted, Nina, 2012, In: Natural Product Research. 26, 1, p. 56-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Trojan horse in drug development: targeting of thapsigargins towards prostate cancer cells
Christensen, Søren Brøgger, Skytte, D. M., Denmeade, S. R., Dionne, C., Møller, J. V., Nissen, P. & Isaacs, J. T., 2009, In: Anti-Cancer Agents in Medicinal Chemistry. 9, 3, p. 276-294Research output: Contribution to journal › Journal article › Research › peer-review
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A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopies
Jalkanen, K. J., Gale, J. D., Lassen, P. R., Hemmingsen, Lars Bo Stegeager, Rodarte, A., Degtyarenko, I. M., Nieminen, R. M., Knapp-Mohammady, M., Suhai, S. & Christensen, Søren Brøgger, 2008, In: Theoretical Chemistry Accounts. 119, 1-3, p. 177-190 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new flavonol glycoside and other flavonoids from the aerial parts of Taverniera aegyptiaca
Hassan, A. R., Amer, K. F., El-Toumy, S. A., Nielsen, J. & Christensen, Søren Brøgger, 2019, In: Natural Product Research. 33, 8, p. 1135-1139Research output: Contribution to journal › Journal article › Research › peer-review
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A new oxygenated ursane derivative from Canthium multiflorum
Traore, M., Jaroszewski, J. W., Olsen, C. E., Ouédraogo, J. B., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2008, In: Planta Medica. 74, 5, p. 560-562 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new sesquiterpene from laserpitium latifolium
Moldt, P., Smitt, U. W. & Christensen, Søren Brøgger, 1 Sep 1987, In: Journal of Natural Products. 50, 5, p. 974-975 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa
Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, Søren Brøgger, Søhoel, H. & Massanet, G. M., 2010, In: Planta Medica. 76, 3, p. 284-290Research output: Contribution to journal › Journal article › Research › peer-review
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A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa
Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P. & Karazmi, A., 22 Jun 2000, In: Planta Medica. 66, 4, p. 396-398 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases
Treiman, M., Caspersen, C. & Christensen, Søren Brøgger, 1 Jan 1998, In: Trends in Pharmacological Sciences. 19, 4, p. 131-135 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute configuration and antiprotozoal activity of minquartynoic acid
Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P., Kharazmi, A. & Huansi, A. G., 2000, In: Journal of Natural Products. 63, 9, p. 1295-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute configurations of the histamine liberating sesquiterpene lactones thapsigargin and trilobolide
Christensen, Søren Brøgger & Norup, E., 1985, In: Tetrahedron Letters. 26, 1, p. 107-110 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerating the domestication of new crops: feasibility and approaches
Østerberg, J. T., Xiang, Wen, Olsen, L. I., Edenbrandt, A. K., Vedel, S. E., Christiansen, Andreas, Landes, X., Andersen, M. M., Pagh-Rasmussen, Peter, Sandøe, Peter, Nielsen, J., Christensen, Søren Brøgger, Thorsen, Bo Jellesmark, Kappel, Klemens, Gamborg, Christian & Palmgren, Michael, 2017, In: Trends in Plant Science. 22, 5, p. 373-384 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: New strategies going beyond the standard
Kongstad, Kenneth Thermann, Ebild, S. J., Christensen, Søren Brøgger, Godejohann, M. & Jaroszewski, J. W., 28 Dec 2012, In: Journal of Chromatography A. 1270, p. 171-177 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alkamides from Phyllanthus fraternus
Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amaryllidaceae alkaloids from Rauhia multiflora (Kunth) Ravenna
Birkholm, T., Rasmussen, N., Christensen, Søren Brøgger, Jäger, A. & Rønsted, Nina, Aug 2011, In: Planta Medica. 77, 12, PG12.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity
Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In: Biochemical Systematics and Ecology. 39, 2, p. 153-155Research output: Contribution to journal › Journal article › Research › peer-review
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Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells
Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, Søren Brøgger, Denmeade, S. R. & Isaacs, J. T., 2009, In: Molecular Cancer Therapeutics. 8, 5, p. 1340-1349Research output: Contribution to journal › Journal article › Research › peer-review
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An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro
Larsen, Erik, Kharazmi, A., Christensen, L. P. & Christensen, Søren Brøgger, 1 Jul 2003, In: Journal of Natural Products. 66, 7, p. 994-995 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An antileishmanial chalcone from Chinese licorice roots
Christensen, Søren Brøgger, Ming, C., Andersen, L., Hjørne, U., Olsen, C. E., Cornett, Claus, Theander, Thor Grundtvig & Kharazmi, A., 1994, In: Planta Medica. 60, 2, p. 121-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An antiplasmodial lignan from Euterpe precatoria
Jensen, J. F., Kvist, L. P. & Christensen, Søren Brøgger, 1 Dec 2002, In: Journal of Natural Products. 65, 12, p. 1915-1917 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An attempt to develop an ELISA against the sesquiterpene lactone thapsigargin
Jager, A. K., Smitt, U. W., Nyman, U. & Christensen, Søren Brøgger, 1 Dec 1993, In: Planta Medica. 59, 7 SUPPL., p. A679Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of the stimulative effect of thapsigargin, a non‐TPA‐type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages
Ohuchi, K., Sugawara, T., Watanabe, M., Hirasawa, N., Tsurufuji, S., Fujiki, H., Christensen, Søren Brøgger & Sugimura, T., Jul 1988, In: British Journal of Pharmacology. 94, 3, p. 917-923 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrocladinium A and B, the first N,C-coupled naphthyldihydroisoquinoline alkaloids, from a Congolese Ancistrocladus species
Bringmann, G., Kajahn, I., Reichert, M., Pedersen, S. E. H., Faber, J. H., Gulder, T., Brun, R., Christensen, Søren Brøgger, Ponte-Sucre, A., Moll, H., Heubl, G. & Mudogo, V., 8 Dec 2006, In: Journal of Organic Chemistry. 71, 25, p. 9348-9356 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine A, the first 5,3’-coupled naphtylisoquinoline alkaloid, and two further, 5,8’-linked related compounds from the newly described species Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K. & Christensen, Søren Brøgger, 2003, In: Journal of Natural Products. 66, p. 1159-1165Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine C and related 5,1’- and 7,3’- coupled naphtylisoquinoline alkaloids from Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, Søren Brøgger, 2004, In: Journal of Natural Products. 67, p. 743-748Research output: Contribution to journal › Journal article › Research › peer-review
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Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani
Chen, M., Christensen, Søren Brøgger, Theander, Thor Grundtvig & Kharazmi, A., 1994, In: Antimicrobial Agents and Chemotherapy. 38, 6, p. 1339-44 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiplasmodial Constituents of Cajanus cajan
Duker-Eshun, G., Jaroszewski, J. W., Asomaning, W. A., Oppong-Boachie, F. & Christensen, Søren Brøgger, 1 Feb 2004, In: Phytotherapy Research. 18, 2, p. 128-130 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx
Oketch-Rabah, H. A., Christensen, Søren Brøgger, Frydenvang, Karla Andrea, Dossaji, S. F., Theander, Thor Grundtvig, Cornett, Claus, Watkins, W. M., Kharazmi, A. & Lemmich, E., 1998, In: Planta Medica. 64, 6, p. 559-62 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase
Singh, P., Mhaka, A. M., Christensen, Søren Brøgger, Gray, J. J., Denmeade, S. R. & Isaacs, J. T., 21 Apr 2005, In: Journal of Medicinal Chemistry. 48, 8, p. 3005-3014 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Are we ready for back-to-nature crop breeding?
Palmgren, Michael, Edenbrandt, A. K., Vedel, S. E., Andersen, M. M., Landes, X., Østerberg, J. T., Falhof, J., Olsen, L. I., Christensen, Søren Brøgger, Sandøe, Peter, Gamborg, Christian, Kappel, Klemens, Thorsen, Bo Jellesmark & Pagh-Rasmussen, Peter, 2015, In: Trends in Plant Science. 20, 3, p. 155-164 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Atriplex nummularia, a source for the two molluscicide saponins: Hederagenin-3-O-β-D-glucuronopyranoside and calenduloside E
Christensen, Søren Brøgger & Omar, A. A., 1 Dec 1985, In: Journal of Natural Products. 48, 1, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioassay-guided identification and isolation of anticancer components in Hypholoma fasciculare extract
Pang, W. S. K., Chen, M., Zhai, L. & Christensen, Søren Brøgger, 2008.Research output: Contribution to conference › Poster › Research
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Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy
Andersen, T. B., Rasmussen, S. A., Christensen, Søren Brøgger & Simonsen, H. T., Jan 2019, In: Phytochemistry. 157, https://doi.org/10.1016/j.phytochem.2018.10.027, p. 168-174 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CA2+-ATPASE INHIBITORY ACTIVITY OF A LOCKED ANALOG OF THAPSIGARGIN
Andersen, A., Treiman, M., Poulsen, J. C. J., Cornett, Claus, Moldt, P., Olsen, C. E. & Christensen, Søren Brøgger, 1994, In: Bioorganic & Medicinal Chemistry Letters. 4, 5, p. 657-660 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ca2+-ATPase inhibitory activity of a locked analogue of thapsigargin
Christensen, Søren Brøgger, Olsen, C. E., Moldt, P., Cornett, Claus, Poulsen, J. J., Treiman, M. & Andersen, A., 1994, In: Bioorganic & Medicinal Chemistry Letters.Research output: Contribution to journal › Journal article › Research › peer-review
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Ca2+ influx in human T lymphocytes is induced independently of inositol phosphate production by mobilization of intracellular Ca2+ stores. A study with the Ca2+ endoplasmic reticulum‐ATPase inhibitor thapsigargin
Gouy, H., Cefai, D., Christensen, Søren Brøgger, Debré, P. & Bismuth, G., Oct 1990, In: European Journal of Immunology. 20, 10, p. 2269-2275 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calcium entry in Xenopus oocytes: effects of inositol trisphosphate, thapsigargin and DMSO
Lupu-Meiri, M., Beit-Or, A., Christensen, Søren Brøgger & Oron, Y., Feb 1993, In: Cell Calcium. 14, 2, p. 101-110 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae
Rønsted, Nina, Symonds, M. R. E., Birkholm, T., Christensen, Søren Brøgger, Meerow, A. W., Schmidt, M. M., Mølgaard, Per, Petersen, G., Rasmussen, N., van Staden, J., Stafford, G. I. & Jäger, A., 14 Sep 2012, In: BMC Evolutionary Biology. 12, 12 p., 182.Research output: Contribution to journal › Journal article › Research › peer-review
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Carroll rearrangement to construct the norneolignan skeleton
Skytte, D. M., Rasmussen, H. B. & Christensen, Søren Brøgger, 2008, In: Natural Product Research. 22, 2, p. 116-123Research output: Contribution to journal › Journal article › Research › peer-review
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Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components
Lindner, P., Christensen, Søren Brøgger, Nissen, Poul, Moller, J. V. & Engedal, N., 2020, In: Cell Communication and Signaling. 18, 23 p., 12.Research output: Contribution to journal › Journal article › Research › peer-review
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Chalcone inhibitors of the NorA efflux pump in Staphylococcus aureus whole cells and enriched everted membrane vesicles
Holler, J. G., Slotved, H., Mølgaard, Per, Olsen, C. E. & Christensen, Søren Brøgger, 2012, In: Bioorganic & Medicinal Chemistry. 20, 14, p. 4514 - 4521 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)
Saaby, Lasse, Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In: Planta Medica. 76, 12, p. 1171Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Chemo- and regioselective functionalization of nortrilobolide: application for semi-synthesis of the natural product 2-acetoxytrilobolide
Doan, T. Q. N., Crestey, F., Olsen, C. E. & Christensen, Søren Brøgger, 2015, In: Journal of Natural Products. 78, 6, p. 1406-1414Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of the Effects of Thapsigargin and BAY K 8644 on Spontaneous Mechanical Activity in Rat Portal Vein and Contractile Responses of Rat Cardiac Muscle
Mikkelsen, E. O., Poulsen, S. H. & Christensen, Søren Brøgger, Feb 1992, In: Pharmacology & Toxicology. 70, 2, p. 152-156 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Concise Synthesis of Thapsigargin from Nortrilobolide
Crestey, F., Toma, M. & Christensen, Søren Brøgger, 8 Sep 2015, In: Tetrahedron Letters. 56, 43, p. 5896-5898 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)
Tung, T., Dao, T. T., Junyent, M. G., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 8 Jan 2018, In: ChemMedChem. 13, 1, 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds
Thanh Tung, T., Christensen, Søren Brøgger & Nielsen, J., 25 Oct 2017, In: Chemistry - A European Journal. 2 p.Research output: Contribution to journal › Journal article › Communication
ID: 1300951
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The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed
Research output: Contribution to journal › Journal article › Research › peer-review
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343
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Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae
Research output: Contribution to journal › Journal article › Research › peer-review
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308
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Demethoxycurcumin is a potent inhibitor of P-type ATPases from diverse kingdoms of life
Research output: Contribution to journal › Journal article › Research › peer-review
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