Osman Asghar Mirza
Associate Professor
Biopharmaceuticals
Jagtvej 162, 2100 København Ø
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Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells
Yu, J., Lubinsky, D., Tsomaia, N., Huang, Z., Taylor, L., Mierke, D., Navarro, J., Mirza, Osman Asghar & Polgar, P., 2007, In: Journal of Cellular Biochemistry. 101, 1, p. 192-204Research output: Contribution to journal › Journal article › Research › peer-review
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An Optimized Screen Reduces the Number of GA Transporters and provides Insights into NPF Substrate Determinants
Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawia, M. S., Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 2019, bioRxiv.Research output: Working paper › Preprint
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An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants
Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter
Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, Osman Asghar, Krusong, K., Carpenter, E. P., Rutherford, N. G., Hadden, J. M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S. G., Hope, R. J., Norbertczak, H. T., Roach, P. C. J., Iwata, S., Henderson, P. J. F. & Cameron, A. D., 2008, In: Science. 322, 5902, p. 709-713Research output: Contribution to journal › Journal article › Research › peer-review
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Over-expression, purification and characterization of an Asc-1 homologue from Gloeobacter violaceus
Wang, X., Hald, H., Ernst, H. A., Egebjerg, J., Christensen, K. V., Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Mirza, Osman Asghar, 2010, In: Protein Expression and Purification. 71, 2, p. 179-183Research output: Contribution to journal › Journal article › Research › peer-review
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Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production
Ullah, R., Shah, M. A., Tufail, S., Ismat, F., Imran, M., Iqbal, M., Mirza, Osman Asghar & Rhaman, M., 2016, In: PloS one. 11, 4, 13 p., e0153436.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of potent epitopes on hexon capsid protein and their evaluation as vaccine candidates against infections caused by members of Adenoviridae family
Tufail, S., Shah, M. A., Zafar, M., Asif, T. A., Shehzad, A., Shah, M. S., Habib, M., Saleemi, M. K., Muddassar, M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2021, In: Vaccine. 39, 27, p. 3560-3564 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Highly soluble and stable ‘insertion domain’ of the capsid penton base protein provides complete protection against infections caused by fowl adenoviruses
Tufail, S., Shah, M. A., Asif, T. A., Ullah, R., Shehzad, A., Ismat, F., Shah, M. S., Habib, M., Calisto, B. M., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2022, In: Microbial Pathogenesis. 173, Part A, 6 p., 105835.Research output: Contribution to journal › Journal article › Research › peer-review
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Restraining the multidrug efflux transporter STY4874 of Salmonella Typhi by reserpine and plant extracts
Tariq, A., Sana, M., Shaheen, A., Ismat, F., Mahboob, S., Rauf, W., Mirza, Osman Asghar, Iqbal, M. & Rahman, M., 2019, In: Letters in Applied Microbiology. 69, 3, p. 161-167Research output: Contribution to journal › Journal article › Research › peer-review
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Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains
Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193Research output: Contribution to journal › Journal article › Research › peer-review
The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection
Tanabe, M., Atkins, H. S., Harland, D. N., Elvin, S. J., Stagg, A. J., Mirza, Osman Asghar, Titball, R. W., Byrne, B. & Brown, K. A., Jun 2006, In: Infection and Immunity. 74, 6, p. 3687-91 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis
Sprogøe, D., van den Broek, L. A. M., Mirza, Osman Asghar, Kastrup, Jette Sandholm Jensen, Voragen, A. G. J., Gajhede, Michael & Skov, L., 10 Feb 2004, In: Biochemistry. 43, 5, p. 1156-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis
Spangfort, M. D., Mirza, Osman Asghar, Ipsen, H., Van Neerven, R. J. J., Gajhede, Michael & Larsen, J., 2003, In: Journal of Immunology. 171, 6, p. 3084-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment
Spangfort, M. D., Mirza, Osman Asghar & Gajhede, Michael, Dec 1999, In: Acta Crystallographica. Section D: Biological Crystallography. 55, Pt 12, p. 2035-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anandamide and 2-AG Are Endogenously Present within the Laterodorsal Tegmental Nucleus: Functional Implications for a role of eCBs in arousal
Soni, N., Prabhala, B. K., Mehta, V., Mirza, Osman Asghar & Kohlmeier, Kristi Anne, Jun 2017, In: Brain Research. 1665, p. 74-79 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose
Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., van der Veen, B., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 1 Jan 2006, In: Biocatalysis and Biotransformation. 24, 1-2, p. 99-105 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity
Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., Dar, I., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 6 Dec 2002, In: Journal of Biological Chemistry. 277, 49, p. 47741-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure of amylosucrase from Deinococcus radiodurans has an unusual open active-site topology
Skov, L. K., Pizzut-Serin, S., Remaud-Simeon, M., Ernst, H. A., Gajhede, Michael & Mirza, Osman Asghar, Sep 2013, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 69, Pt 9, p. 973-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Crystallization and preliminary X-ray studies of recombinant amylosucrase from Neisseria polysaccharea
Skov, L. K., Mirza, Osman Asghar, Henriksen, A., Potocki de Montalk, G., Remaud-Simeon, M., Sarcabal, P., Willemot, R. M., Monsan, P. & Gajhede, M., Feb 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 2, p. 203-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family
Skov, L. K., Mirza, Osman Asghar, Henriksen, A., De Montalk, G. P., Remaud-Simeon, M., Sarçabal, P., Willemot, R. M., Monsan, P. & Gajhede, Michael, 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 25273-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide Selectivity of the Proton-Coupled Oligopeptide Transporter from Neisseria meningitidis
Sharma, N., Aduri, N. G., Iqbal, A., Prabhala, B. K. & Mirza, Osman Asghar, 2016, In: Journal of Molecular Microbiology and Biotechnology. 26, 5, p. 312-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars
Shaheen, A., Tariq, A., Iqbal, M., Mirza, Osman Asghar, Haque, A., Walz, T. & Rahman, M., 2021, In: Antibiotics. 10, 12, 26 p., 1455.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of the multidrug efflux transporter styMdtMfrom Salmonella enterica serovar Typhi
Shaheen, A., Ismat, F., Iqbal, M., Haque, A., Ul-Haq, Z., Mirza, Osman Asghar, De Zorzi, R., Walz, T. & Rahman, M., 2021, In: Proteins: Structure, Function, and Bioinformatics. 89, 9, p. 1193-1204Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional regulation of drug resistance mechanisms in Salmonella: where we stand and what we need to know
Shaheen, A., Tariq, A., Shehzad, A., Iqbal, M., Mirza, Osman Asghar, Maslov, D. A. & Rahman, M., 2020, In: World journal of microbiology & biotechnology. 36, 6, 8 p., 85.Research output: Contribution to journal › Review › Research › peer-review
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Characterization of putative multidrug resistance transporters of the major facilitator-superfamily expressed in Salmonella Typhi
Shaheen, A., Ismat, F., Iqbal, M., Haque, A., De Zorzi, R., Mirza, Osman Asghar, Walz, T. & Rahman, M., 2015, In: Journal of Infection and Chemotherapy. 21, 5, p. 357–362 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302772
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Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol
Research output: Contribution to journal › Journal article › Research › peer-review
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Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]
Research output: Contribution to journal › Journal article › Research › peer-review
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Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published