Paul Robert Hansen

Paul Robert Hansen

Associate Professor


  1. Published

    Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency

    Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A., Berg, Jais Oliver, Thulstrup, Peter Waaben, Franzyk, Henrik, Edvinsson, L., Sams, A., Sheykhzade, Majid & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences (Online). 21, 4, p. 1-15 15 p., 1343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    bdrF2 of lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection

    Zhang, H., Raji, A., Theisen, M., Hansen, Paul Robert & Marconi, R. T., 2005, In: Journal of Bacteriology. 187, 1, p. 175-184 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Identifying immunogenic CD4+ T-cell epitopes of Myeloid cell leukemia 1 using overlapping 20-mer peptides spanning the whole protein.

    Woodworth, J. S., Agger, E. M. & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium Ved Srivastava, Andrei Yudin, and Michal Lebl (Editors) American Peptide Society. p. 262-63 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  4. Published

    Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation

    Woodworth, J., Aagaard, C., Hansen, Paul Robert, Cassidy, J., Agger, E. M. & Andersen, P., 2014, In: The Journal of Immunology. 192, 7, p. 3247-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

    Wester, A., Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

    Welner, S., Trier, N. H., Houen, G. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 2, p. 95-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

    Welner, S., Trier, N. H., Morten Frisch, M., Locht, H., Hansen, Paul Robert & Houen, G., 2013, In: Molecular Cancer. 12, 1, 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen

    Weinreich Olsen, A., Hansen, Paul Robert, Holm, A. & Andersen, P., 2000, In: European Journal of Immunology. 30, p. 1724-1732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Fine mapping of glutamate decarboxylase 65 epitopes reveals dependency of hydrophobic amino acids for specific interactions

    Valdarnini, N., Holm, B., Hansen, Paul Robert, Rovero, P., Houen, G. & Trier, N. H., 2019, In: International Journal of Molecular Sciences (Online). 20, 13 p., 2909.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structural features of peptoid-peptide hybrids in lipid-water interfaces

    Uggerhøj, L. E., Munk, J. K., Hansen, Paul Robert, Güntert, P. & Wimmer, R., 2014, In: F E B S Letters. 588, 17, p. 3291–3297 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Rational Design of alpha-helical antimicrobial peptides: DOs and DON’Ts

    Uggerhøj, L. E., Poulsen, T. J., Munk, J. K., Fredborg, M., Sondergaard, T. E., Frimodt-Møller, N., Hansen, Paul Robert & Wimmer, R., 2015, In: ChemBioChem. 16, 2, p. 242–253 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2

    Tronstrøm, J., Dragborg, A. H., Hansen, Paul Robert, Houen, G. & Trier, N. H., 2014, In: Protein and Peptide Letters. 21, 1, p. 25-31 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Cross-reactivity of a human IgG1 anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

    Trier, N. H., Leth, M. L., Hansen, Paul Robert & Houen, G., 31 Dec 2012, In: Protein Science. 21, 12, p. 1929-1941

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C

    Trier, N. H., Valdarnini, N., Fanelli, I., Rovero, P., Hansen, Paul Robert, Schafer, C., Ciplys, E., Slibinskas, R., Pociot, F., Friis, T. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 16 p., 4424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Production and characterization of peptide antibodies

    Trier, N. H., Hansen, Paul Robert & Houen, G., 2012, In: Methods. 56, 2, p. 136-144 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Identification of continuous epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

    Trier, N. H., Hansen, Paul Robert, Vedeler, C. A., Somnier, F. E. & Houen, G., 2012, In: Journal of Neuroimmunology. 243, 1, p. 25-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Identification of linear epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

    Trier, N. H., Hansen, Paul Robert & Houen, G., 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  18. Published

    Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

    Trier, N. H., Dam, C., Olsen, D., Hansen, Paul Robert & Houen, G., 2015, In: P L o S One. p. 1-12 12 p., 0144707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis

    Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 30 Jun 2020, Jenny Stanford Publishing Pte. Ltd. ( Current Issues in Medicine: Surgical and Medical Specialities).

    Research output: Book/ReportBookResearchpeer-review

  20. Published

    Specific Reactivity of Anti-Citrullinated Protein Antibodies to Citrullinated Peptides Associated with Rheumatoid Arthritis

    Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 1 Jan 2021, Advances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data. R. B. (ed.). Jenny Stanford Publishing Pte. Ltd, p. 41-54 14 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  21. Published

    Peptides, antibodies, peptide antibodies and more

    Trier, N., Hansen, Paul Robert & Houen, G., 11 Nov 2019, In: International Journal of Molecular Sciences (Online). 20, 22 p., 6289.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

    Trier, N., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 2019, In: Antibodies. 8, 2, 10 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Analogues of a Cyclic Antimicrobial Peptide with a Flexible Linker Show Promising Activity Against Pseudomonas aeruginosa and Staphylococcus aureus

    Thomsen, T. T., Mendel, H. C., Al-Mansour, W., Oddo, A., Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: Antibiotics. 9, 7, 13 p., 366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Fallaxin: Optimization of cleavage conditions following solid-phase synthesis

    Søndergaard, S. L., Christensen, U. & Hansen, Paul Robert, 2006.

    Research output: Contribution to conferencePosterResearch

  25. Published

    Fallaxin analogues with improved antibacterial activity

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2009, Peptides for Youth: the proceedings of the 20th American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 531-532 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  26. Published

    Structure-activity study of the antibacterial peptide fallaxin

    Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Fallaxin: optimization of cleavage conditions following solid-phase synthesis

    Søndergaard, S. L., Hansen, Paul Robert & Christensen, U., 2007, Ikke angivet. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, p. 498-499 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  28. Published

    Fallaxin analogues with improved antibacterial activity

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  29. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  30. Published

    Fallaxin: Correlation of antibacterial activity with mean hydrophobicity <H> and mean hydrophobic moment <µ>

    Søndergaard, S. L., Frimodt-Møller, N. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  31. Published

    Laboratorieøvelser i kemi: prælab, checklister og datalister

    Springborg, J. & Hansen, Paul Robert, 2001, 2. ed. København: Jordbrugsforlaget. 40 p.

    Research output: Book/ReportBookEducation

  32. Published

    Laboratorieøvelser i kemi: for studerende under valgsystemet

    Springborg, J. & Hansen, Paul Robert, 2001, 2. ed. København: Jordbrugsforlaget. 125 p.

    Research output: Book/ReportBookEducation

  33. Published

    Laboratorieøvelser i kemi: for studerende under valgsystemet ved Kemisk Institut, Den Kgl. Veterinær- og Landbohøjskole

    Springborg, J. & Hansen, Paul Robert, 2000, København: Jordbrugsforlaget. 131 p.

    Research output: Book/ReportBookEducation

  34. Published

    Efficient, regioselective ring-opening of activated aziridine-2-carboxylates with [18F]fluoride

    Schjøth-Eskesen, C., Hansen, Paul Robert, Kjær, Andreas & Gillings, N., 2015, In: ChemistryOpen. 4, 1, p. 65–71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    [64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

    Schjøth-Eskesen, C., Nielsen, Carsten Haagen, Heissel, S., Højrup, P., Hansen, Paul Robert, Gillings, N. & Kjær, A., 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Peptide binding specificity of the chaperone calreticulin

    Sandhu, N., Duus, K., Jørgensen, C. S., Hansen, Paul Robert, Bruun, S. W., Pedersen, L. Ø., Højrup, P. & Houen, G., 2007, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 6, p. 701-713 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

    Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

    Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Accepted/In press

    The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

    Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Review on abyssomicins: Inhibitors of the chorismate pathway and folate biosynthesis

    Sadaka, C., Ellsworth, E., Hansen, Paul Robert, Ewin, R., Damborg, Peter Panduro & Watts, J. L., 2018, In: Molecules. 23, 6, 25 p., 1371.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    Identification of antibacterial lysine-peptoid hybrids using a mixture-based combinatorial library

    Ryge, T. S. & Hansen, Paul Robert, 2006. 4 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  42. Published

    Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi

    Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008, In: Chemotherapy. 54, 2, p. 152-156 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

     Antimicrobial activities of Lysine-Peptoid Hybrids against Clinically Relevant Bacteria and Fungi

    Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008.

    Research output: Contribution to conferencePosterResearch

  44. Published

    Design, synthesis and characterization of novel antibacterial lysine-peptoid hybrids

    Ryge, T. S. & Hansen, Paul Robert, 2004. 4 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  45. Published

    Potent antibacterial lysine-peptoid hybrids identified from a positional scanning combinatorial library

    Ryge, T. S. & Hansen, Paul Robert, 2006, In: Bioorganic & Medicinal Chemistry. 14, 13, p. 4444-4451 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Novel lysine-peptoid hybrids with antibacterial properties

    Ryge, T. S. & Hansen, Paul Robert, 2005, In: Journal of Peptide Science. 11, 11, p. 727-734 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    N-terminal derivatized analogues of indolicidin and [Phe4,6,8,9,11]indolicidin with enhanced antibacterial activity

    Ryge, T. S. & Hansen, Paul Robert, 2004. 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  48. Published

    Trypsin stability of lysine-peptoid hybrids

    Ryge, T. S. & Hansen, Paul Robert, 2009, Peptides for youth: the proceedings of the 20. American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 581-582 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  49. Published

    N-acetylcysteine-chitosan nanoparticles with the Ctx(Ile21)-Ha peptide grafted onto the surface can rescue the susceptibility of pre-extensively resistant Mycobacterium tuberculosis

    Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2 Oct 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  50. Published

    Rifampicin-loaded N-acetylcysteine-chitosan nanoparticles surface-grafted with a peptide exhibit potent activity against multidrug-resistant Mycobacterium tuberculosis

    Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 11 Jun 2023. 1 p.

    Research output: Contribution to conferencePosterResearchpeer-review

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