Paul Robert Hansen

Paul Robert Hansen

Associate Professor

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    ORCID: 0000-0001-9357-8001

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    1. Published

       Impact of newly synthesized antimicrobial peptides on Staphylococcus aureus

      Gottschalk, S., Søndergaard, S. L., Hansen, Paul Robert, Ingmer, Hanne & Thomsen, Line Elnif, 2008. 1 p.

      Research output: Contribution to conference › Poster › Research

    2. Published

       Antimicrobial activities of Lysine-Peptoid Hybrids against Clinically Relevant Bacteria and Fungi

      Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008.

      Research output: Contribution to conference › Poster › Research

    3. Published

      bdrF2 of lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection

      Zhang, H., Raji, A., Theisen, M., Hansen, Paul Robert & Marconi, R. T., 2005, In: Journal of Bacteriology. 187, 1, p. 175-184 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      [64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

      Schjøth-Eskesen, C., Nielsen, Carsten Haagen, Heissel, S., Højrup, P., Hansen, Paul Robert, Gillings, N. & Kjær, A., 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Use of resin-bound peptides for epitope mapping of a monoclonal anti-gliadin antibody related to celiac disease

      Petersen, N. H., Hansen, Paul Robert & Houen, G., 25 Jun 2011.

      Research output: Contribution to conference › Poster › Research

    6. Published

      Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

      Litman, Thomas, Jensen, U., Hansen, Alastair, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 20 Sep 2002, In: BBA General Subjects. 1565, 1, p. 6-16 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

      Litman, T., Jensen, U., Hansen, Axel Kornerup, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 2002, In: Biochimica et Biophysica Acta - Biomembranes. 1565, 1, p. 6-16 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Two novel synthetic peptoids exhibit rapid in vitro killing of methicillin-resistant Staphylococcus pseudintermedius

      Damborg, Peter Panduro, Hansen, Paul Robert & Guardabassi, Luca, 2011. 1 p.

      Research output: Contribution to conference › Poster › Research

    9. Published

      Trypsin stability of lysine-peptoid hybrids

      Neerup, T. S. R. & Hansen, Paul Robert, 2007. 1 p.

      Research output: Contribution to conference › Poster › Research

    10. Published

      Trypsin stability of lysine-peptoid hybrids

      Ryge, T. S. & Hansen, Paul Robert, 2009, Peptides for youth: the proceedings of the 20. American Peptide Symposium. Valle, S. D., Escher, E. & Lubell, W. D. (eds.). Springer Science+Business Media, p. 581-582 2 p. (Advances in Experimental Medicine and Biology, Vol. 611).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    11. Published

      The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

      Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, Paul Robert, Brasen, C., Gajhede, Michael, Rahman, M. & Mirza, Osman Asghar, 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      The interaction between calreticulin and immunoglobulin G and immunoglobulin Y

      Møllegaard, K. M., Duus, K., Træholt, S. D., Thaysen-Andersen, M., Liu, Y., Palma, A. S., Feizi, T., Hansen, Paul Robert, Højrup, P. & Houen, G., 2011, In: B B A - Proteins and Proteomics. 1814, 7, p. 889-899 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide

      Oddo, A., Nyberg, N., Frimodt-Møller, N., Thulstrup, Peter Waaben & Hansen, Paul Robert, 2015, In: European Journal of Medicinal Chemistry. 102, p. 574-581 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      The effect of Cys15 and Cys21 replacement with Ala, Ser and Lys on the anti Mycobacterium tuberculosis activity of antimicrobial peptide B1CTcu5

      Roque-Borda, C. A., Costa de Pontes, J. T., Domingos da Silva, L. H., Caroline dos Santos, I. C. D. S., Aparecida Resende, F., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2023.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    15. Published

      The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases

      Pagh, R., Duus, K., Laursen, I., Hansen, Paul Robert, Mangor, J., Thielens, N., Arlaud, G. J., Kongerslev, L., Højrup, P. & Houen, G., 2008, In: FEBS Journal. 275, 3, p. 515-526 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

      Gottschalk, S., Ifrah, D., Søndergaard, S. L., Gottlieb, C. T., Cohn, M. T., Hiasa, H., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 2013, In: B M C Microbiology. 13, 8 p., 192.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Accepted/In press

      The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

      Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      The Structure of the Central Side Chain is Crucial for Anoplin Hemolytic Activity

      Munk, J., Thøgersen, L., Uggerhøj, L. E., Wimmer, R., Frimodt-Møller, N., Lindorff-Larsen, Kresten & Hansen, Paul Robert, 2013, Proceedings of the 23rd American Peptide Symposium. Lebl, M. (ed.). American Peptide Society

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    19. Published

      Teoretiske øvelser i kemi: opgavehæfte

      Larsen, Erik & Hansen, Paul Robert, 2001, 2. ed. København: Jordbrugsforlaget. 258 p.

      Research output: Book/Report › Book › Education

    20. Published

      Synthetic analogs of anoplin show improved antimicrobial activities

      Munk, J., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Møller, N., Wimmer, R., Nyberg, N. T. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 11, p. 669-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Synthesis of antimicrobial peptoids

      Hansen, Paul Robert & Munk, J., 2013, Peptide synthesis and applications. 2nd ed. Vol. 1047. p. 151-159 (Methods in Molecular Biology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    22. Published

      Synthesis of Peptoids Containing MultipleNhtrp andNtrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection

      Lone, A., Arnous, A., Hansen, Paul Robert, Mojsoska, B. & Jenssen, H., 2020, In: Frontiers in Chemistry. 8, 12 p., 370.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Synthesis of 2-acetamido-2-deoxy- beta-D-glucopyranose O-glycopeptides from N-dithiasuccinoyl-protected derivatives

      Jensen, Knud Jørgen, Hansen, Paul Robert, Venugopal, D. & Barany, G., 1996, In: Journal of the American Chemical Society. 118, 13, p. 3148-3155 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Synthesis and raman spectroscopic studies of the antimicrobial peptide cecropin B2

      Ladefoged Nielsen, S., Doisy, X., Hansen, Paul Robert & Faurskov Nielsen, O., 2005.

      Research output: Contribution to conference › Poster › Research

    25. Published

      Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

      Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

      Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, Peter Waaben, Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Molecules. 24, 6, 16 p., 1121.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Structure-activity study of the antibacterial peptide fallaxin

      Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Structure-activity relationship study of anoplin

      Ifrah, D., Doisy, X., Ryge, T. S. & Hansen, Paul Robert, 2005, In: Journal of Peptide Science. 11, p. 113-121 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Structure-activity relationship studies of lysine-based α-peptide/β-peptoid antimicrobial peptidomimetics

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2017. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    30. Published

      Structure-Activity Study of an All-D Antimicrobial Octapeptide D2D

      Lone, A., Thomsen, T. T., Nielsen, J. E., Thulstrup, Peter Waaben, Klitgaard, R. N., Løbner-Olesen, Anders, Lund, R., Jenssen, H. & Hansen, Paul Robert, 2019, In: Molecules. 24, 24, 17 p., 4571.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Structure-Activity Relationship Study of Lysine-Based Antimicrobial α-Peptide/β-Peptoid Oligomers

      Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 2015.

      Research output: Contribution to conference › Poster › Research

    32. Published

      Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography

      Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Structural features of peptoid-peptide hybrids in lipid-water interfaces

      Uggerhøj, L. E., Munk, J. K., Hansen, Paul Robert, Güntert, P. & Wimmer, R., 2014, In: F E B S Letters. 588, 17, p. 3291–3297 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Specificity of anti-citrullinated protein antibodies to citrullinated α-enolase peptides as a function of epitope structure and composition

      Fanelli, I., Rovero, P., Hansen, Paul Robert, Fredriksen, Jette Lautrup, Houen, G. & Trier, N. H., 2021, In: Antibodies. 10, 3, 12 p., 27.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

      Trier, N., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 2019, In: Antibodies. 8, 2, 10 p., 37.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis

      Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 30 Jun 2020, Jenny Stanford Publishing Pte. Ltd. ( Current Issues in Medicine: Surgical and Medical Specialities).

      Research output: Book/Report › Book › Research › peer-review

    37. Published

      Specific Reactivity of Anti-Citrullinated Protein Antibodies to Citrullinated Peptides Associated with Rheumatoid Arthritis

      Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 1 Jan 2021, Advances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data. R. B. (ed.). Jenny Stanford Publishing Pte. Ltd, p. 41-54 14 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    38. Published

      Solid-phase synthesis of O-glycopeptides from N-dithiasuccinoyl-protected D-glucosamine derivatives

      Hansen, Paul Robert, Jensen, Knud Jørgen & Barany, G., 1995, In: Peptides. 1994, p. 729-730 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Solid-Phase Peptide Synthesis of Human alfa-Calcitonin Gene-Related Peptide and Two Fluorescent Analogs.

      Fuente-Moreno, M., Oddo, A., Sheykhzade, Majid, Pickering, Darryl S & Hansen, Paul Robert, 2015, Proceedings of the 24th American Peptide Symposium . 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    40. Published

      Small analogues of lysozyme with antibacterial properties

      Doisy, X., Ifrah, D., Neerup, T. S. & Hansen, Paul Robert, 2003.

      Research output: Contribution to conference › Poster › Research

    41. Published

      Small analogues of lysozyme with antibacterial properties

      Doisy, X., Ifrah, D., Neerup, T. S. & Hansen, Paul Robert, 2003. 2 p.

      Research output: Contribution to conference › Paper › Research

    42. Published

      Single amino acid substitution analogues of the antibacterial peptide [A7]-anoplin

      Hansen, Paul Robert, Ifrah, D., Lianee, H. T., Thing, C. S. & Vitved, T., 2006, Peptides 2006: proceedings of the twenty-ninth European Peptide Symposium. Rolka, K., Rekowski, P. & Silberring, J. (eds.). Kenes International, p. 284-285 2 p.

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

    43. Published

      Single Amino Acid Substitution Analogues of The  Antibacterial Peptide [A7]-Anoplin

      Hansen, Paul Robert, Ifrah, D., Lianee, H., Thing, C. S. & Vitved, T., 2006.

      Research output: Contribution to conference › Poster › Research

    44. Published

      Short linear peptide-peptoid hybrids as potential antimicrobial drugs: Abstract for the 24th American Peptide Symposium

      Greco, I., Damborg, Peter Panduro, Jana, B. & Hansen, Paul Robert, 1 Jun 2015.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    45. Published

      Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

      Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Secondary structure and association of melittin during and after solid-phase synthesis: a Raman and static light scattering study

      Lund Hansen, C., Hansen, Paul Robert, Callisen, T. H., Bauer, R. & Faurskov Nielsen, O., 2002, In: Journal of Raman Spectroscopy. 33, 3, p. 142-146 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Second-generation nanofiltered plasma-derived mannan-binding lectin product: process and characteristics

      Laursen, I., Houen, G., Højrup, P., Brouwer, N., Krogsøe, L. B., Blou, L. & Hansen, Paul Robert, 2007, In: Vox Sanguinis. 92, 4, p. 338-350 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Roles of hydrophobicity, fluorination and distribution of cationic residues in α-peptide/β-peptoids for antibacterial and hemolytic properties

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2016. 1 p.

      Research output: Contribution to conference › Poster › Research

    49. Published

      Ring flexibility as a key design feature for cyclic antimicrobial peptides

      Oddo, A., Frimodt-Møller, N. & Hansen, Paul Robert, 4 Jun 2014.

      Research output: Contribution to conference › Poster › Research › peer-review

    50. Published

      Rifampicin-loaded N-acetylcysteine-chitosan nanoparticles surface-grafted with a peptide exhibit potent activity against multidrug-resistant Mycobacterium tuberculosis

      Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 11 Jun 2023. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

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