Anders Bach
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
- 2012
- Published
A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage
Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ligand binding by PDZ domains
Chi, C. N., Bach, Anders, Strømgaard, Kristian, Gianni, S. & Jemth, P., 2012, In: BioFactors. 38, 5, p. 338-348 (Review) 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains
Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In: Journal of the American Chemical Society. 134, 1, p. 599-605Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801
Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, J., Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In: Neuropharmacology. 67, p. 193-200 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy
Fiorentini, M., Bach, Anders, Strømgaard, Kristian, Kastrup, Jette Sandholm Jensen & Gajhede, Michael, Apr 2013, In: Acta Crystallographica. Section D: Biological Crystallography. 69, Pt 4, p. 587-94 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Energetic pathway sampling in a protein interaction domain
Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In: Structure. 21, 7, p. 1193-1202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Møller, T. C., Wirth, V. F., Roberts, N. I., Bender, J., Bach, Anders, Jacky, B. P. S., Strømgaard, Kristian, Deussing, J. M., Schwartz, Thue W. & Martinez, Karen Laurence, 2013, In: PLOS ONE. 8, 5, e63352.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Benzoxazolone carboxamides as potent acid ceramidase inhibitors: Synthesis and structure-activity relationship (SAR) studies
Bach, A.*; Pizzirani, D.*; Realini, N.; Vozella, V.; Russo, D.; Penna, I.; Melzig, L.; Scarpelli, R.; Piomelli, D. (*Shared 1st authors), B. A. *. P. D. *. R. N. ;. V. V. ;. R. D. ;. P. I. ;. M. L. ;. S. R. ;. P. D. (. 1. A., 2015, In: Journal of Medicinal Chemistry. 58, 23, p. 9258-9272 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzoxazolone derivatives as Acid Ceramidase inhibitors, and their use as medicaments
Piomelli, D; Pagliuca, C.; Pizzirani, D.; Bach, A.; Realini, N.; De Vivo, M, P. D. P. C. ;. P. D. ;. B. A. ;. R. N. ;. D. V. M., 19 Nov 2015, Patent No. WO2015/173168A1, Priority date 12 May 2014, Priority No. IT/MI2014/A000863Research output: Patent
- Published
Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions
Bach, Anders*; Pedersen, Søren W.; Dorr, Liam A.; Vallon, Gary; Ripoche, Isabelle; Ducki, Sylvie; Lian, Lu-Yun* (*Corresponding), B. A. P. S. W. ;. D. L. A. ;. V. G. R. I. D. S. L. L. (., 2015, In: Scientific Reports. 5, p. 1-12 12 p., 12157.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1304261
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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286
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A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Research output: Contribution to journal › Journal article › Research › peer-review
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165
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Molecular architecture of the Jumonji C family histone demethylase KDM5B
Research output: Contribution to journal › Journal article › Research › peer-review
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