Anders Bach

Anders Bach

Professor


  1. 2020
  2. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery

    Solbak, Sara Marie Øie, Zang, J., Narayanan, Dilip, Høj, L. J., Bucciarelli, S., Softley, C., Meier, S., Langkilde, Annette Eva, Gotfredsen, C. H., Sattler, M. & Bach, Anders, 2020, In: Journal of Medicinal Chemistry. 63, 3, p. 1156-1177

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, Sara Marie Øie, Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In: Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2021
  6. Published

    Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds

    Pallesen, J. S., Narayanan, Dilip, Tran, K. T., Solbak, Sara Marie Øie, Marseglia, G., Sørensen, L. M. E., Høj, L. J., Munafò, F., Carmona, R. M. C., Garcia, A. D., Desu, H. L., Brambilla, R., Johansen, Tommy Nørskov, Popowicz, G. M., Sattler, M., Gajhede, Michael & Bach, Anders, 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4623–4661

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

    Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Identification of novel fragments binding to the PDZ1-2 domain of PSD-95

    Zang, J., Ye, F., Solbak, Sara Marie Øie, Høj, L. J., Zhang, M. & Bach, Anders, 2021, In: ChemMedChem. 16, 6, p. 949-954

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

    Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, L., Buijink, J. A., Mende, F., Jin, C., Jepsen, Sara Lind, Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, 2021, In: Molecular Metabolism. 49, 14 p., 101207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery

    Quancard, J., Bach, Anders, Cox, B., Craft, R., Finsinger, D., Guéret, S. M., Hartung, I. V., Laufer, S., Messinger, J., Sbardella, G. & Koolman, H. F., 2021, In: ChemMedChem. 16, 11, p. 1737-1740

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2022
  12. Published

    Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery

    Narayanan, Dilip, Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, Michael & Bach, Anders, 2022, In: Journal of Medicinal Chemistry. 65, 21, p. 14481-14526

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

    Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1304261