Anders Bach

Anders Bach

Professor

ORCID: 0000-0003-4305-9910

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  1. Published

    Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95

    Eildal, J. N. N., Bach, Anders, Dogan, J., Ye, F., Zhang, M., Jemth, P. & Strømgaard, Kristian, 2015, In: ChemBioChem. 16, p. 64–69 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

    Grunddal, K. V., Diep, T. A., Petersen, N., Tough, I. R., Skov, Louise Julie, Liu, L., Buijink, J. A., Mende, F., Jin, C., Jepsen, Sara Lind, Sørensen, L. M. E., Achiam, Michael Patrick, Strandby, R. B., Bach, Anders, Hartmann, Bolette, Frimurer, Thomas Michael, Hjorth, Siv Annegrethe, Bouvier, M., Cox, H. & Holst, Birgitte, 2021, In: Molecular Metabolism. 49, 14 p., 101207.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, Anders, Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, Henrik, Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-Hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, Kristian, May 2019, In: Neuropharmacology. 150, p. 100-111 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains

    Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In: Journal of the American Chemical Society. 134, 1, p. 599-605

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Small-molecule modulators of tumor necrosis factor signaling

    Chédotal, H., Narayanan, Dilip, Povlsen, K., Gotfredsen, C. H., Brambilla, R., Gajhede, Michael, Bach, Anders & Clausen, M. H., 2023, In: Drug Discovery Today. 28, 6, 103575.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, T. S., Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In: Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Substituted benzoxazolone derivatives as Acid Ceramidase inhibitors, and their use as medicaments

    Piomelli, D; Pizzirani, D.; Bach, A.; Scarpelli, R.; Melzig, L.; Mor, M. , P. D. P. D. ;. B. A. ;. S. R. ;. M. L. ;. M. M., 19 Nov 2015, Patent No. WO2015/173169A1, Priority date 12 May 2014, Priority No. IT/MI2014/A000862

    Research output: Patent

  8. Published

    Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors

    Zang, J., Peters, F., Cambet, Y., Cifuentes-Pagano, E., Hissabu, M. M. S., Dustin, C. M., Svensson, L. H., Olesen, M. M., Poulsen, M. F. L., Jacobsen, Stig, Tuelung, P. S., Narayanan, Dilip, Langkilde, Annette Eva, Gajhede, Michael, Pagano, P. J., Jaquet, V., Vilhardt, Frederik & Bach, Anders, 2023, In: Journal of Medicinal Chemistry. 66, 21, p. 14963–15005

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Targeting Oxidative Stress in Stroke

    Bach, Anders, Jan 2017, Neuroprotective Therapy for Stroke and Ischemic Disease. Lapchak, P. & Zhang, J. H. (eds.). Springer, p. 203-250 (Translational Stroke Research).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    Targeting Protein-Protein Interactions with Trimeric Ligands: High Affinity Inhibitors of the MAGUK Protein Family

    Nissen, K. B., Kedström, L. M. H., Wilbek, T. S., Nielsen, L. S., Åberg, E., Kristensen, Anders Skov, Bach, Anders, Jemth, P. & Strømgaard, Kristian, 2015, In: PLOS ONE. 10, 2, p. 1-17 17 p., e0117668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment

    Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, Madsen, Kenneth Lindegaard & Clemmensen, Christoffer, 2024, In: Science Advances. 10, 9, 20 p., eadg2636.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Targeting protein-protein interactions: inhibitors of c-Myc/Max and PDZ domain proteins

    Bach, Anders, 2009, København: Det Farmaceutiske Fakultet. 196 p.

    Research output: Book/Report › Ph.D. thesis › Research

  13. Published

    The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo

    Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, Burak, Strømgaard, K., Bach, Anders, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation

    Quancard, J., Vulpetti, A., Bach, Anders, Cox, B., Guéret, S. M., Hartung, I. V., Koolman, H. F., Laufer, S., Messinger, J., Sbardella, G. & Craft, R., 2023, In: ChemMedChem. 18, 9, e202300002.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery

    Quancard, J., Bach, Anders, Cox, B., Craft, R., Finsinger, D., Guéret, S. M., Hartung, I. V., Laufer, S., Messinger, J., Sbardella, G. & Koolman, H. F., 2021, In: ChemMedChem. 16, 11, p. 1737-1740

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The dynamics of linear polyubiquitin

    Jussupow, A., Messias, A. C., Stehle, R., Geerlof, A., Solbak, Sara Marie Øie, Paissoni, C., Bach, Anders, Sattler, M. & Camilloni, C., Oct 2020, In: Science Advances. 6, 42, 13 p., eabc3786.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801

    Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, J., Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In: Neuropharmacology. 67, p. 193-200 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Unique interaction pattern for a functionally biased ghrelin receptor agonist

    Sivertsen, B. B., Lang, M., Frimurer, T. M., Holliday, N. D., Bach, Anders, Els, S., Engelstoft, M. S., Petersen, P. S., Madsen, A. N., Schwartz, Thue W., Beck-Sickinger, A. G. & Holst, Birgitte, 10 Jun 2011, In: The Journal of Biological Chemistry. 286, 23, p. 20845-20860 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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