Anders Skov Kristensen

Anders Skov Kristensen

Associate Professor


Publication year:
All
1 - 50 out of 76Page size: 50
Sort by: 1st author
  1. Published

    Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter

    Andersen, J., Olsen, L., Hansen, K. B., Taboureau, O., Jørgensen, Flemming Steen, Jørgensen, A. M., Bang-Andersen, B., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2010, In: Journal of Biological Chemistry. 285, 3, p. 2051-2063

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands

    Andersen, J., Ladefoged, L. K., Kristensen, T. N. B., Munro, L., Grouleff, J., Stuhr-Hansen, N., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 19 Oct 2016, In: A C S Chemical Neuroscience. 7, 10, p. 1406-1417 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Binding of the Multimodal Antidepressant Drug Vortioxetine to the Human Serotonin Transporter

    Andersen, J., Ladefoged, L. K., Wang, D., Kristensen, T. N. B., Bang-Andersen, B., Kristensen, Anders Skov, Schiøtt, B. & Strømgaard, Kristian, 18 Nov 2015, In: A C S Chemical Neuroscience. 6, 11, p. 1892-900 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Molecular basis for selective serotonin reuptake inhibition by the antidepressant agent fluoxetine (prozac)

    Andersen, J., Stuhr-Hansen, N., Zachariassen, L. G., Koldsø, H., Schiøtt, B., Strømgaard, Kristian & Kristensen, Anders Skov, May 2014, In: Molecular Pharmacology. 85, 5, p. 703-14 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Antidepressive lægemidler: nu i 3D

    Andersen, J., Sørensen, L., Strømgaard, Kristian & Kristensen, Anders Skov, Dec 2010, In: Lægemiddelforskning. 2010, p. 25-27

    Research output: Contribution to journal › Journal article › Communication

  6. Published

    Binding site residues control inhibitor selectivity in the human norepinephrine transporter but not in the human dopamine transporter

    Andersen, J., Ringsted, K. B., Bang-Andersen, B., Strømgaard, Kristian & Kristensen, Anders Skov, 2015, In: Scientific Reports. 5, p. 1-12 12 p., 15650.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Location of the antidepressant binding site in the serotonin transporter: importance of SER-438 in recognition of citalopram and tricyclic antidepressants

    Andersen, J., Taboureau, O., Hansen, K. B., Olsen, L., Egebjerg, J., Strømgaard, Kristian & Kristensen, Anders Skov, 2009, In: Journal of Biological Chemistry. 284, 15, p. 10276-10284

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Molecular determinants for selective recognition of antidepressants in the human serotonin and norepinephrine transporters

    Andersen, J., Stuhr-Hansen, N., Zachariassen, L., Toubro, S., Hansen, S. M. R., Eildal, J. N. N., Bond, A. D., Bøgesø, K. P., Bang-Andersen, B., Kristensen, Anders Skov & Strømgaard, Kristian, 19 Jul 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 29, p. 12137-12142

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters

    Andersen, J., Kristensen, Anders Skov, Bang-Andersen, B. & Strømgaard, Kristian, 2009, In: Chemical Communications. 25, p. 3677-3692

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDA receptor interaction

    Bach, Anders, Chi, C. N., Pang, G. F., Olsen, L., Kristensen, Anders Skov, Jemth, P. & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 51, p. 9685-9689

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Protein-protein interaktion: et nyt mål for udvikling af lægemidler

    Bach, Anders, Gottschalk, M., Kristensen, Anders Skov & Strømgaard, Kristian, 2008, In: Lægemiddelforskning. p. 10-12

    Research output: Contribution to journal › Journal article › Communication

  12. Published

    Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction

    Bach, Anders, Eildal, J. N. N., Stuhr-Hansen, N., Deeskamp, R., Gottschalk, M., Pedersen, S. W., Kristensen, Anders Skov & Strømgaard, Kristian, 10 Mar 2011, In: Journal of Medicinal Chemistry. 54, 5, p. 1333-1346

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A high-affinity, dimeric inhibitor of PSD-95 bivalently interacts with PDZ1-2 and protects against ischemic brain damage

    Bach, Anders, Clausen, B. H., Møller, M., Vestergaard, Bente, Chi, C. N., Round, A., Sørensen, P. L., Nissen, K. B., Kastrup, Jette Sandholm Jensen, Gajhede, Michael, Jemth, P., Kristensen, Anders Skov, Lundström, P., Lambertsen, K. L. & Strømgaard, Kristian, 28 Feb 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 9, p. 3317-3322

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata

    Barslund, A. F., Poulsen, Mette Homann, Bach, T. B., Lucas, S., Kristensen, Anders Skov & Strømgaard, Kristian, 2011, In: Journal of Natural Products. 74, 3, p. 483-486

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure

    Bay, Y., Venskutonytė, R., Frantsen, S. M., Thorsen, T. S., Musgaard, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Biggin, P. C., Kristensen, Anders Skov, Boesen, T., Pickering, Darryl S, Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2024, In: FEBS Journal. 291, 7, p. 1506-1529

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2

    Bay, Y., Egeberg Jeppesen, M., Frydenvang, Karla Andrea, Francotte, P., Pirotte, B., Pickering, Darryl S, Kristensen, Anders Skov & Kastrup, Jette Sandholm Jensen, 2024, In: FEBS Letters. 598, 7, p. 743-757

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

    Bjerrum, E. J., Kristensen, Anders Skov, Pickering, D. S., Greenwood, J. R., Nielsen, Birgitte, Liljefors, T., Schousboe, Arne, Bräuner, Hans, Madsen, Ulf & Pickering, Darryl S, 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Structure-Activity Relationship and Solubility Studies of Novel N1-substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Nielsen, B., Bay, Y., Kristensen, Anders Skov, Hinkkanen, M., Szczepańska, K., Karcz, T., Latacz, G., Johansen, Tommy Nørskov & Szymanska, E. M., 2023, In: ChemMedChem. 18, 18, 15 p., e202300278.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

    Chałupnik, P., Vialko, A., Pickering, Darryl S, Hinkkanen, M., Donbosco, S., Møller, T. C., Jensen, Anders A., Nielsen, Birgitte, Bay, Y., Kristensen, Anders Skov, Johansen, Tommy Nørskov, Łątka, K., Bajda, M. & Szymańska, E., 2022, In: International Journal of Molecular Sciences. 23, 15, 16 p., 8797.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Deciphering the kinetic binding mechanism of dimeric ligands using a potent plasma-stable dimeric inhibitor of postsynaptic density protein-95 as an example

    Chi, C. N., Bach, Anders, Gottschalk, M., Kristensen, Anders Skov, Strømgaard, Kristian & Jemth, P., 2010, In: Journal of Biological Chemistry. 285, 36, p. 28252-28260

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization

    Clausen, Rasmus Prætorius, Naur, P., Kristensen, Anders Skov, Greenwood, J. R., Strange, M., Bräuner, Hans, Jensen, Anders A., Nielsen, A. S. T., Geneser, U., Ringgaard, L. M., Nielsen, Birgitte, Pickering, Darryl S, Brehm, L., Gajhede, Michael, Krogsgaard-Larsen, Povl & Kastrup, Jette Sandholm Jensen, 2009, In: Journal of Medicinal Chemistry. 52, 15, p. 4911-4922

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: Synthesis and structure-activity relationship studies

    Eildal, J. N. N., Andersen, J., Kristensen, Anders Skov, Jørgensen, A. M., Bang-Andersen, B., Jørgensen, M. & Strømgaard, Kristian, 2008, In: Journal of Medicinal Chemistry. 51, 10, p. 3045-3048

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

    Erreger, K., Geballe, M. T., Kristensen, Anders Skov, Chen, P. E., Hansen, K. B., Lee, C. J., Yuan, H., Le, P., Lyuboslavsky, P. N., Micale, N., Jørgensen, L., Clausen, Rasmus Prætorius, Wyllie, D. J. A., Snyder, J. P. & Traynelis, S. F., 2007, In: Molecular Pharmacology. 72, 4, p. 907-920

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists

    Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors

    Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.

    Research output: Contribution to conference › Poster › Research

  26. Published

    Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction

    Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Neurochemical Research. 34, 10, p. 1729-1737

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3

    Hackney, Celeste Menuet, Flórez Salcedo, P., Mueller, E., Koch, Thomas Lund, Kjelgaard, L. D., Watkins, M., Zachariassen, L., Tuelund, P. S., McArthur, J. R., Adams, D. J., Kristensen, Anders Skov, Olivera, B., Finol-Urdaneta, R. K., Safavi-Hemami, H., Morth, J. P. & Ellgaard, Lars, 2023, In: PLOS Biology. 21, 8, 32 p., e3002217.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Modulation of the dimer interface at ionotropic glutamate-like receptor d2 by D-serine and extracellular calcium

    Hansen, K. B., Naur, P., Kurtkaya, N. L., Kristensen, Anders Skov, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., 2009, In: Journal of Neuroscience. 29, 4, p. 907-917

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome

    Ismail, V., Zachariassen, L. G., Godwin, A., Sahakian, M., Ellard, S., Stals, K. L., Baple, E., Brown, K. T., Foulds, N., Wheway, G., Parker, M. O., Lyngby, S. M., Pedersen, M. G., Desir, J., Bayat, Allan, Musgaard, M., Guille, M., Kristensen, Anders Skov & Baralle, D., 2022, In: American Journal of Human Genetics. 109, 7, p. 1217-1241

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Expressed protein ligation of ionotropic glutamate receptors

    Jensen, M. S., Kristensen, Anders Skov & Strømgaard, Kristian, 2007, In: Biopolymers. 88, 4, p. 602

    Research output: Contribution to journal › Conference abstract in journal › Research

  31. Published

    Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization

    Jørgensen, L., Nielsen, Birgitte, Pickering, Darryl S, Kristensen, Anders Skov, Frydenvang, Karla Andrea, Madsen, Ulf & Clausen, Rasmus Prætorius, 2014, In: Neurochemical Research. 39, 10, p. 1895-1905 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209

    Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

    Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In: Pharmacological Reviews. 63, 3, p. 585-640 56 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Neuroscience: an intrusive chaperone

    Kristensen, Anders Skov & Traynelis, S. F., 23 Jun 2005, In: Nature. 435, 7045, p. 1042-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors

    Kristensen, Anders Skov, Hansen, K. B., Naur, P., Olsen, L., Kurtkaya, N. L., Dravid, S. M., Kvist, T., Yi, F., Pøhlsgaard, J., Clausen, Rasmus Prætorius, Gajhede, Michael, Kastrup, Jette Sandholm Jensen & Traynelis, S. F., Feb 2016, In: Molecular Pharmacology. 89, 2, p. 253-262 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Glutamate receptors: variation in structure-function coupling

    Kristensen, Anders Skov, Geballe, M. T., Snyder, J. P. & Traynelis, S. F., Feb 2006, In: Trends in Pharmacological Sciences. 27, 2, p. 65-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

    Kristensen, Anders Skov, Larsen, M. B., Johnsen, L. B. & Wiborg, O., Mar 2004, In: European Journal of Neuroscience. 19, 6, p. 1513-23 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Kristensen, Anders Skov, Jenkins, M. A., Banke, T. G., Schousboe, Arne, Makino, Y., Johnson, R. C., Huganir, R. & Traynelis, S. F., 1 Jun 2011, In: Nature Neuroscience. 14, 6, p. 727-735

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Structural correlates of ionotropic glutamate receptor function

    Kristensen, Anders Skov, Hansen, K. B., Wollmuth, L. P., Egebjerg, J. & Traynelis, S. F., 2007, The receptors: The glutamate receptors. Gereau, R. W. & Swanson, G. T. (eds.). 1. ed. Totowa N.J., USA: Humana Press, p. 247-299 42 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  40. Published

    Glutamate receptors: variation in structure-function coupling

    Kristensen, Anders Skov, Geballe, M., Snyder, J. P. & Traynelis, S. F., Feb 2006, In: Trends in Pharmacological Sciences. 27, 2, p. 65-69 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Neuroscience: an intrusive chaperone

    Kristensen, Anders Skov, 23 Jun 2005, In: Nature. 435, 7045, p. 1042-1043 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Modeling and Mutational Analysis of the Binding Mode for the Multimodal antidepressant Drug Vortioxetine to the Human 5-HT 3A Receptor

    Ladefoged, L. K., Munro, L., Pedersen, A. J., Lummis, S. C. R., Bang-andersen, B., Balle, T., Schiøtt, B. & Kristensen, Anders Skov, 1 Dec 2018, In: Molecular Pharmacology. 94, 6, p. 1421-1434

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors

    Lucas, S., Poulsen, Mette Homann, Nørager, N. G., Barslund, A. F., Bach, T. B., Kristensen, Anders Skov & Strømgaard, Kristian, 26 Nov 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10297-10301 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1

    Lund, Trine Meldgaard, Christensen, E., Kristensen, Anders Skov, Schousboe, Arne & Lund, Allan Meldgaard, 2004, In: Journal of Neuroscience Research. 77, 1, p. 143-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Molecular cloning, expression and characterization of a bovine serotonin transporter

    Mortensen, O. V., Kristensen, Anders Skov, Rudnick, G. & Wiborg, O., 23 Jul 1999, In: Brain Research. 71, 1, p. 120-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants

    Mortensen, O. V., Kristensen, Anders Skov & Wiborg, O., Oct 2001, In: Journal of Neurochemistry. 79, 2, p. 237-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Conformational Changes in the 5-HT3A Receptor Extracellular Domain Measured by Voltage-Clamp Fluorometry

    Munro, L., Ladefoged, L. K., Padmanathan, V., Andersen, S., Schiott, B. & Kristensen, Anders Skov, 1 Dec 2019, In: Molecular Pharmacology. 96, 6, p. 720-734

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Ionotropic glutamate-like receptor d2 binds D-serine and glycine.

    Naur, P., Hansen, K. B., Kristensen, Anders Skov, Dravid, S. M., Pickering, Darryl S, Olsen, L., Vestergaard, Bente, Egebjerg, J., Gajhede, Michael, Traynelis, S. F. & Kastrup, Jette Sandholm Jensen, 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 35, p. 14116-14121

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors

    Nelson, J. K., Frølund, S. U., Tikhonov, D. B., Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Angewandte Chemie - International Edition. 48, 17, p. 3087-3091

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 Next

ID: 1302186