Blanca Aldana

Blanca Aldana

Associate Professor

ORCID: 0000-0002-5027-1218

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  1. Published

    Decanoic Acid Rescues Differences in AMPA-Mediated Calcium Rises in Hippocampal CA1 Astrocytes and Neurons in the 5xFAD Mouse Model of Alzheimer's Disease

    Abghari, M., Vu, J. T. C. M., Eckberg, N., Aldana, Blanca & Kohlmeier, Kristi Anne, 2023, In: Biomolecules. 13, 10, 25 p., 1461.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells

    Aldana, Blanca, Waagepetersen, Helle S., Schousboe, Arne, White, H. S., Bulaj, G. & Walls, Anne Byriel, Nov 2017, In: Journal of Neuroscience Research. 95, 11, p. 2286-2296 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons

    Aldana, Blanca, Zhang, Y., Lihme, M. F., Bak, Lasse Kristoffer, Nielsen, Jørgen Erik, Holst, B., Hyttel, P., Freude, Kristine & Waagepetersen, Helle S., 2017, In: Neurochemistry International. 106, p. 48-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia

    Aldana, Blanca, Zhang, Y., Jensen, P., Chandrasekaran, Abinaya, Christensen, S. K., Nielsen, T. T., Nielsen, Jørgen Erik, Hyttel, P., Larsen, M. R., Waagepetersen, Helle S. & Freude, Kristine, 2020, In: Molecular Brain. 13, 1, 7 p., 125.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cellular bioenergetics in human iPSC-derived glutamatergic neurons in health and disease

    Aldana, Blanca, Salcedo, C., Freude, Kristine & Waagepetersen, Helle S., 2021, Current Progress in iPSC-derived Cell Types. Birbrair, A. (ed.). Elsevier, p. 205-221 17 p. (Advances in Stem Cell Biology, Vol. 10).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. Published

    Microglia-Specific Metabolic Changes in Neurodegeneration

    Aldana, Blanca, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1830-1842

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Sertraline inhibits pre-synaptic Na + channel-mediated responses in hippocampus-isolated nerve endings

    Aldana, Blanca & Sitges, M., Apr 2012, In: Journal of Neurochemistry. 121, 2, p. 197-205 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Fats, Friends or Foes: Investigating the Role of Short- and Medium-Chain Fatty Acids in Alzheimer’s Disease

    Ameen, Aisha, Freude, Kristine & Aldana, Blanca, 2022, In: Biomedicines. 10, 11, 2778.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer's Disease

    Andersen, Jens Velde, Christensen, S. K., Aldana, Blanca, Nissen, J. D., Tanila, H. & Waagepetersen, Helle S., Jun 2017, In: Neurochemical Research. 42, 6, p. 1589–1598

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex

    Andersen, Jens Velde, Jakobsen, Emil, Westi, Emil Winther, Lie, M. E. K., Voss, C. M., Aldana, Blanca, Schousboe, Arne, Wellendorph, Petrine, Bak, Lasse Kristoffer, Pinborg, Lars Hageman & Waagepetersen, Helle S., 2020, In: Glia. 68, 12, p. 2601-2612

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria

    Andersen, Jens Velde, Jakobsen, Emil, Waagepetersen, Helle S. & Aldana, Blanca, 2019, In: Journal of Neuroscience Research. 97, p. 961–974

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply

    Andersen, Jens Velde, Westi, Emil Winther, Jakobsen, Emil, Urruticoechea, N., Borges, K. & Aldana, Blanca, 2021, In: Molecular Brain. 14, 1, 13 p., 132.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    β-Hydroxybutyrate and Medium-Chain Fatty Acids are Metabolized by Different Cell Types in Mouse Cerebral Cortex Slices

    Andersen, Jens Velde, Westi, Emil Winther, Neal, E. S., Aldana, Blanca & Borges, K., 2023, In: Neurochemical Research. 48, p. 54–61

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  15. Published

    Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration

    Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease

    Andersen, Jens Velde, Skotte, Niels Henning, Aldana, Blanca, Nørremølle, Anne & Waagepetersen, Helle S., 2019, In: Cellular and Molecular Life Sciences. 76, 12, p. 2449-2461

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Accepted/In press

    Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex

    Andersen, Jens Velde, Westi, Emil Winther, Griem-Krey, Nane, Skotte, Niels Henning, Schousboe, Arne, Aldana, Blanca & Wellendorph, Petrine, 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

    Andersen, Jens Velde, Christensen, S. K., Westi, Emil Winther, Diaz-delcastillo, M., Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, Helle S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Role of Histaminergic System in Blood-Brain Barrier Dysfunction Associated with Neurological Disorders

    Bañuelos-Cabrera, I., Valle-Dorado, M. G., Aldana, Blanca, Orozco-Suárez, S. A. & Rocha, L., 1 Nov 2014, In: Archives of Medical Research. 45, 8, p. 677-686 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Mutation in FTD3 CHMP2B causes impaired autography and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conference › Conference abstract for conference › Research

  21. Published

    Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3

    Chandrasekaran, A., Dittlau, K. S., Corsi, G. I., Haukedal, H., Doncheva, N. T., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Zhang, Y., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J. E., Kolko, M., Kobolák, J., Dinnyés, A., Hyttel, P., Palakodeti, D. & 5 others, Gorodkin, Jan, Muddashetty, R. S., Meyer, M., Aldana, Blanca & Freude, Kristine, 2021, In: Stem Cell Reports. 16, 11, p. 2736-2751

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Mutations in FTD3 CHMP2B causes impaired autophagy and distorted energy metabolism cumulating in reactive astrocyte phenotypes

    Chandrasekaran, A., Dittlau, K. S., Corsi, G., Doncheva, N. T., Haukedal, H., Ramakrishna, S., Ambardar, S., Salcedo, C., Schmidt, S. I., Cirera, S., Pihl, M., Schmid, B., Nielsen, T. T., Nielsen, J., Kolko, M., Kobolak, J., Dinnyes, A., Hyttel, P., Palakodeti, D., Gorodkin, J. & 4 others, Muddashetty, R., Meyer, M., Aldana, Blanca & Freude, Kristine, 2020.

    Research output: Contribution to conference › Poster › Research

  23. Published

    Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

    Di Ianni, M. E., Enrique, A. V., Del Valle, M. E., Aldana, Blanca, Rosella, M. A., Rocha, L., Castro, E. A., Bruno-Blanch, L. E. & Talevi, A., 2015, In: Combinatorial Chemistry and High Throughput Screening. 18, 4, p. 335-345 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells

    Duwe, Lea, Munoz-Garrido, P., Lewinska, Monika, Lafuente Barquero, Juan Francisco, Satriano, L., Høgdall, Dan Taksony Solyom, Taranta, A., Nielsen, B. S., Ghazal, A., Matter, M. S., Banales, J. M., Aldana, Blanca, Gao, Y., Marquardt, J. U., Roberts, L. R., Oliveira, R. C., Koshiol, J., O'Rourke, Colm & Andersen, Jesper Bøje, 2023, In: Journal of Hepatology. 78, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer

    Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

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