Dan Stærk
Head of Department, Visiting professor
Administration and Operations
Jagtvej 160
2100 København Ø
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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High resolution techniques: General discussion
Adair, E., Afonso, C., Bell, N. G. A., Davies, A. N., Delsuc, M. A., Godfrey, R., Goodacre, R., Hawkes, J. A., Hertkorn, N., Jones, D., Lameiras, P., Le Guennec, A., Lubben, A., Nilsson, M., Paša-Tolić, L., Richards, J., Rodgers, R. P., Rüger, C. P., Schmitt-Kopplin, P., Schoenmakers, P. J. & 8 others, , 1 Jan 2019, In: Faraday Discussions. 218, p. 247-267 21 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Ancient biosynthesis in an oil crop: Glucosinulate profiles in Limnanthes alba and its relatives (Limnanthaceae, Brassicales)
Agerbirk, Niels, Pattison, David, Mandáková, T., Lysak, M. A., Montaut, S. & Stærk, Dan, 2022, In: Journal of Agricultural and Food Chemistry. 70, p. 1134-1147Research output: Contribution to journal › Journal article › Research › peer-review
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1H NMR-based metabolomics combined with HPLC-PDA-MS-SPE-NMR for investigation of standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2010, In: Metabolomics. 6, 2, p. 292-302 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009. 1 p.Research output: Contribution to conference › Poster › Research
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1H-NMR based metabolomics applied to standardized Ginkgo biloba preparations
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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Non-biased investigation of standardized Ginkgo biloba preparations by 1H NMR-based metabolomics and HPLC-PDA-MS-SPE-NMR
Agnolet, S., Jaroszewski, J. W., Verpoorte, R. & Stærk, Dan, 2009.Research output: Contribution to conference › Poster › Research
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Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-perfomance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay
Agnolet, S., Wiese, S., Verpoorte, R. & Stærk, Dan, 2012, In: Journal of Chromatography A. 1262, p. 130-137 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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1H NMR-based metabolomics applied to study of complex pharmaceutical extracts of Ginkgo biloba
Agnolet, S., Jaroszewski, J. W. & Stærk, Dan, 2009.Research output: Contribution to conference › Conference abstract for conference › Research
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Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of C-glucosylated octaketide anthraquinones in Nicotiana benthamiana using a multispecies-based biosynthetic pathway
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nafisi, M., Stærk, Dan, Okkels, F. T., Mortensen, U. H., Møller, Birger Lindberg, Frandsen, R. J. N. & Kannangara, R. M., 2017, In: ChemBioChem. 18, 19, p. 1893-1897 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus
Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, Kenneth Thermann, 2021, In: Molecules. 26, 6, 12 p., 1550.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Labdanes and isopimaranes from Platycladus orientalis and their effects on erythrocyte membrane and on Plasmodium falciparum growth in the erythrocyte host cells
Asili, J., Lambert, M., Ziegler, H. L., Stærk, Dan, Sairafianpour, M., Witt, M., Asghari, G., Ibrahimi, I. & Jaroszewski, J. W., 2004, In: Journal of Natural Products. 67, p. 631-637Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of the antidiabetic potential of selected medicinal plants using in vitro bioassays of muscle glucose transport and liver glucose production
Beidokhti, M. N., Sanchez Villavicencio, M. L., Eid, H. M., Stærk, Dan, Jäger, A. K. & Haddad, P. S., Dec 2016, In: Planta Medica. 81, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Investigation of medicinal plants from Madagascar against DPP-IV linked to type 2 diabetes
Beidokhti, M. N., Lobbens, E. S. B., Rasoavaivo, P., Jäger, A. K. & Stærk, Dan, Mar 2018, In: South African Journal of Botany. 115, p. 113-119Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibitory potential of 40 medicinal plant extracts from Madagascar against enzymes linked to type 2 diabetes
Beidokhti, M. N., Lobbens, E. S., Rasoavaivo, P., Stærk, Dan & Jäger, A. K., 26 Aug 2015.Research output: Contribution to conference › Poster › Research
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Evaluation of the antidiabetic potential of Psidium guajava L. (Myrtaceae) using assays for α-glucosidase, α-amylase, muscle glucose uptake, liver glucose production and triglyceride accumulation in adipocytes
Beidokhti, M. N., Eid, H. M., Villavicencio, M. L. S., Jäger, A. K., Lobbens, E. S., Rasoanaivo, P. R., McNair, Laura M., Haddad, P. S. & Stærk, Dan, 17 Apr 2020, In: Journal of Ethnopharmacology. 257, 8 p., 112877.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of antidiabetic potential of Phyllanthus niruri L. using assays for α-glucosidase, muscle glucose transport, liver glucose production, and adipogenesis
Beidokhti, M. N., Andersen, M. V., Eid, H. M., Villavicencio, M. L. S., Stærk, Dan, Haddad, P. S. & Jäger, A. K., 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 869-874Research output: Contribution to journal › Journal article › Research › peer-review
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Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.
Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.Research output: Contribution to journal › Journal article › Research › peer-review
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Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intact penetratin metabolite permeates across Caco-2 monolayers
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.Research output: Contribution to conference › Poster › Research
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Phytochemical investigation of Eremophila spp.
Bredahl, E. K., Ergin, Y., Kjaerulff, Louise & Stærk, Dan, 2021, p. 1.Research output: Contribution to conference › Poster › Research
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Isolation and structure elucidation of caryophyllane sesquiterpenoids from leaves of Eremophila spathulata
Bredahl, E. K., Kjaerulff, Louise, Ndi, C., Semple, S., Buirchell, B., Møller, Birger Lindberg & Stærk, Dan, 2022, In: Phytochemistry Letters. 47, p. 156-163Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine A, the first 5,3’-coupled naphtylisoquinoline alkaloid, and two further, 5,8’-linked related compounds from the newly described species Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K. & Christensen, Søren Brøgger, 2003, In: Journal of Natural Products. 66, p. 1159-1165Research output: Contribution to journal › Journal article › Research › peer-review
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Ancistrotanzanine C and related 5,1’- and 7,3’- coupled naphtylisoquinoline alkaloids from Ancistrocladus tanzaniensis
Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, Søren Brøgger, 2004, In: Journal of Natural Products. 67, p. 743-748Research output: Contribution to journal › Journal article › Research › peer-review
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NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. & Stærk, Dan, 2015. 1 p.Research output: Contribution to conference › Poster › Research
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Potential of Sorbus berry extracts for management of type 2 diabetes: metabolomics investigation of 1H NMR spectra, α-amylase and α-glucosidase inhibitory activities, and in vivo anti-hyperglycaemic activity of S. norvegica
Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2019, In: Journal of Ethnopharmacology. 242, 10 p., 112061.Research output: Contribution to journal › Journal article › Research › peer-review
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Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Forbedret test af nye lægemidler mod malaria
Christensen, J., Stærk, Dan, Ziegler, H. L., Sairafianpour, M. & Jaroszewski, J. W., 2001, In: Lægemiddelforskning. p. 8-9Research output: Contribution to journal › Journal article › Communication
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19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR
Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182Research output: Contribution to journal › Journal article › Research › peer-review
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Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768Research output: Contribution to journal › Journal article › Research
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Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis.
Chu, C., Li, T., Pedersen, H. A., Kongstad, Kenneth Thermann, Yan, J. & Stærk, Dan, 2019, In: Phytochemistry Letters. 31, p. 47-52Research output: Contribution to journal › Journal article › Research › peer-review
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Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: application of HPLC-DAD-SPE-NMR to identification of constituents of Kanahia laniflora
Clarkson, C., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Analytical Chemistry. 77, p. 3547-3553Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of major and minor constituents of Harpagophytum procumbens (Devil's Claw) using HPLC-SPE-NMR and HPLC-ESIMS/APCIMS
Clarkson, C., Stærk, Dan, Hansen, S. H., Smith, P. J. & Jaroszewski, J. W., 2006, In: Journal of Natural Products. 69, p. 1280-1288Research output: Contribution to journal › Journal article › Research › peer-review
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Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens
Clarkson, C., Stærk, Dan, Hansen, S. H., Smith, P. J. & Jaroszewski, J. W., 2006, In: Journal of Natural Products. 69, p. 527-530Research output: Contribution to journal › Journal article › Research › peer-review
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Microwave-assisted ring-opening of activated aziridines with resin-bound amines
Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analogues of the natural product Sinefungin as inhibitors of EHMT1 and EHMT2
Devkota, K., Lohse, B., Liu, Q., Wang, M., Stærk, Dan, Berthelsen, J. & Clausen, Rasmus Prætorius, 2014, In: A C S Medicinal Chemistry Letters. 5, 4, p. 293-297Research output: Contribution to journal › Letter › Research › peer-review
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Insects as sources for sustainable peptide drugs against type 2 diabetes
Didriksen, A. H., Petersen, M. J. & Stærk, Dan, 8 Jun 2021. 1 p.Research output: Contribution to conference › Poster › Research
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An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara
Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia L.
Ernst, M., Nothias, L., van der Hooft, J. J. J., da Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K. A., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Stærk, Dan, Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, 15 p., 846.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular phylogenetics as a predictive tool in plant-based drug discovery in the genus Euphorbia L.
Ernst, M., Saslis Lagoudakis, H., Grace, O. M., Nilsson, N., Simonsen, H. T., Horn, J. W., Stærk, Dan & Rønsted, Nina, 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis
Forman, Victor, Luo, Dan, Geu-Flores, Fernando, Lemcke, René, Nelson, D., Kampranis, Sotirios, Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2022, In: Nature Communications. 13, 14 p., 5143.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, Kenneth Thermann, Nafisi, M., Kannangara, R. M., Stærk, Dan, Okkels, F. T., Binderup, K., Madsen, B., Møller, Birger Lindberg, Thrane, U. & Mortensen, U. H., 2018, In: Scientific Reports. 8, p. 1-10 10 p., 12853.Research output: Contribution to journal › Journal article › Research › peer-review
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Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum
Frandsen, R. J. N., Schütt, C. W. H., Lund, B. L. W., Stærk, Dan, Nielsen, J., Olsson, S. & Giese, H., 2011, In: Journal of Biological Chemistry. 286, 12, p. 10419-10428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines
Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769Research output: Contribution to journal › Journal article › Research › peer-review
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Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species
Gericke, Oliver, Hansen, N. L., Pedersen, G. B., Kjaerulff, Louise, Luo, Dan, Stærk, Dan, Møller, Birger Lindberg, Pateraki, Irini & Heskes, A., 2020, In: B M C Plant Biology. 20, 15 p., 91.Research output: Contribution to journal › Journal article › Research › peer-review
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Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila
Gericke, Oliver, Fowler, R., Heskes, A., Bayly, M., Semple, S., Ndi, C. P., Stærk, Dan, Loland, Claus Juul, Murphy, D. J., Buirchell, B. & Møller, Birger Lindberg, 2021, In: Plant Journal. 108, 2, p. 555-578Research output: Contribution to journal › Journal article › Research › peer-review
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Picraviane A and B: Nortriterpenes with limonoid-like skeletons containing a heptanolide E-ring system from Picramnia glazioviana
Gimenes, L., Batista Junior, J. M., dos Santos Junior, F. M., Souza, M. D. S., Luna-Dulcey, L., Ellena, J., Cominetti, M. R., da Silva, M. F. D. G. F., Vieira, P. C., Fernandes, J. B. & Stærk, Dan, 2019, In: Phytochemistry. 163, p. 38-45Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299056
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Identification of α-glucosidase inhibitors in apple peel - a chemometric approach
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4032
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Itoside A and 4-hydroxytremulacin from Dovyalis caffra and Dovyalis zeyheri
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Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: Ester and amide formation between citric acid and 5-aminosalicylic acid
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