NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)

Research output: Contribution to conferencePosterResearch

Documents

  • Sofie L. Broholm
  • Simone Gramsbergen
  • Nils Nyberg
  • Anna Jäger
  • Stærk, Dan
Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to control
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
Original languageEnglish
Publication date2015
Number of pages1
Publication statusPublished - 2015
Event36th Danish NMR Meeting - Lund, Sweden
Duration: 19 Jan 201520 Jan 2015

Conference

Conference36th Danish NMR Meeting
CountrySweden
CityLund
Period19/01/201520/01/2015

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