Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

Publication year:
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101 - 150 out of 229Page size: 50
  1. 2015
  2. Published

    High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: accelerated identification of bioactive constituents in food and medicinal plants

    Stærk, Dan, 2015.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  3. Published

    High-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR: α-glucosidase inhibitors and acetylated ellagic acid rhamnosides from Myrcia palustris DC. (Myrtaceae)

    Wubshet, S. G., Moresco, H. H., Tahtah, Y., Brighente, I. M. C. & Stærk, Dan, 2015, In: Phytochemistry. 116, p. 246-252 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Chinese plants used to treat snakebite

    Liu, Y., Stærk, Dan, Nielsen, M. N., Nyberg, N. & Jäger, A. K., 2015, In: Phytochemistry. 119, p. 62-69 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata

    Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A., 2015.

    Research output: Contribution to conference › Poster › Research

  6. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. & Stærk, Dan, 2015.

    Research output: Contribution to conference › Poster › Research

  7. Published

    Identification of Fungal Plasma Membrane H+-ATPase Inhibitors in Lecaniodiscus cupanioides by HPLC-HRMS-SPE-NMR

    Straadt, I. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2015.

    Research output: Contribution to conference › Poster › Research

  8. Published

    Intact penetratin metabolite permeates across Caco-2 monolayers

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.

    Research output: Contribution to conference › Poster › Research

  9. Published

    Investigation of skin permeation, ex vivo inhibition of venom-induced tissue destruction, and wound healing of African plants used against snakebites

    Schmidt, M. M., Stærk, Dan, Nielsen, Hanne Mørck, Brandner, J. M., Diallo, D., Kusamba Zacharie, C., Van Staden, J. & Jäger, A., 2015, In: Journal of Ethnopharmacology. 165, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Magnetic ligand fishing as a targeting tool for HPLC-HRMS-SPE-NMR: α-glucosidase inhibitory ligands and alkylresorcinol glycosides from Eugenia catharinae.

    Wubshet, S. G., Brighente, I. M. C., Moaddel, R. & Stærk, Dan, 2015, In: Journal of Natural Products. 78, 11, p. 2657-2665 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)

    Broholm, S. L., Gramsbergen, S., Nyberg, N., Jäger, A. & Stærk, Dan, 2015. 1 p.

    Research output: Contribution to conference › Poster › Research

  12. Published

    Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude extract of Radix Scutellariae

    Tahtah, Y., Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N., Jønsson, L. H., Jäger, A. K., Qinglei, S. & Stærk, Dan, 2015, In: Journal of Chromatography A. 1408, p. 125-132 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts

    Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    NMR-based metabolomics and hyphenated NMR techniques – a perfect match in natural products research

    Vinther, J. M., Wubshet, S. G. & Stærk, Dan, Aug 2015, Ethnopharmacology - a Reader. Heinrich, M. & Jäger, A. K. (eds.). Chichester: Wiley, p. 63-74

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  17. Published

    High-resolution assays combined with HPLC for identification of antidiabetic constituents in Vietnamese plants

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  18. Published

    High-resolution snake venom inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antivenomous constituents in Clausena excavata

    Liu, Y., Nyberg, N., Stærk, Dan & Jäger, A. K., 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  19. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. K. & Stærk, Dan, 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  20. Published

    Inhibitory potential of 40 medicinal plant extracts from Madagascar against enzymes linked to type 2 diabetes

    Beidokhti, M. N., Lobbens, E. S., Rasoavaivo, P., Stærk, Dan & Jäger, A. K., 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  21. Published

    High-resolution hyaluronidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-necrosis constituents in Clausena excavata

    Liu, Y., Stærk, Dan, Nyberg, N. & Jager, A. K., Nov 2015, In: Planta Medica. 81, 16, p. 1432-1432

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Nyberg, N. T., Sun, Q., Jager, A. K. & Stærk, Dan, Nov 2015, In: Planta Medica. 81, 16, p. 1437-1437

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. 2016
  24. Published

    Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR

    Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis

    Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    HPLC-SPE-NMR for combinatorial biosynthetic investigations – expanding the landscape of diterpene structural diversity

    Kongstad, Kenneth Thermann, Andersen-Ranberg, Johan, Hamberger, B. R. & Stærk, Dan, 2016. 1 p.

    Research output: Contribution to conference › Poster › Research

  27. Published

    High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida

    Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)

    Lana e Silva, E., Felipe Revoredo Lobo, J., Vinther, J. M., Moreira Borges, R. & Stærk, Dan, 2016, In: Molecules. 21, 6, 19 p., 782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Identification of PTP1B and α-glucosidase inhibitory serrulatanes from Eremophila spp. by combined use of dual high-resolution PTP1B and α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR

    Wubshet, S. G., Tahtah, Y., Heskes, A. M., Kongstad, Kenneth Thermann, Pateraki, Irini, Hamberger, B. R., Møller, Birger Lindberg & Stærk, Dan, 2016, In: Journal of Natural Products. 79, 4, p. 1063-1072 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Molecular phylogenetics as a predictive tool in plant-based drug discovery in the genus Euphorbia L.

    Ernst, M., Saslis Lagoudakis, H., Grace, O. M., Nilsson, N., Simonsen, H. T., Horn, J. W., Stærk, Dan & Rønsted, Nina, 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  31. Published

    Oxidation and cyclization of Casbene in the biosynthesis of Euphorbia factors from mature seeds of Euphorbia lathyris L

    Luo, Dan, Callari, R., Hamberger, B., Wubshet, S. G., Nielsen, M. T., Andersen-Ranberg, Johan, Hallström, B. M., Cozzi, F., Heider, H., Møller, Birger Lindberg, Stærk, Dan & Hamberger, B. R., 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. E5082-E5089 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Screening for potential α-glucosidase and α-amylase inhibitory constituents from selected Vietnamese plants used to treat type 2 diabetes

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 2016, In: Journal of Ethnopharmacology. 186, p. 189-195 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Spektroskopi – Strukturopklaring vha NMR og IR: Kompendium med forelæsningsslides, tabeller og opgavesamling til en undervisningsdag i spektroskopi ved Institut for Lægemiddeldesign og Farmakologi på Det Sundhedsvidenskabelige Fakultet, Københavns Universitet.

    Stærk, Dan, 2016, 74 p.

    Research output: Book/Report › Compendium/lecture notes › Education

  34. Published

    Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study

    Olsson, T., MacMillan, H. A., Nyberg, N., Stærk, Dan, Malmendal, A. & Overgaard, J., 15 Aug 2016, In: The Journal of Experimental Biology. 219, 16, p. 2504-2513 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Accelerating drug lead discovery from nature by high-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR

    Kongstad, Kenneth Thermann, Nyberg, N. T., Wubshet, S. G. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    Assessment of the antidiabetic potential of selected medicinal plants using in vitro bioassays of muscle glucose transport and liver glucose production

    Beidokhti, M. N., Sanchez Villavicencio, M. L., Eid, H. M., Stærk, Dan, Jäger, A. K. & Haddad, P. S., Dec 2016, In: Planta Medica. 81, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  37. Published

    HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  38. Published

    HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl

    de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    High-resolution α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of anti-diabetic compounds in Eremanthus crotonoides (Asteraceae)

    Silva, E. L., Lobo, J., Vinther, J. M., Borges, R. M. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Ligand-fishing and bioactivity-correlated metabolomics for accelerated discovery of antidiabetic drug leads

    Nyberg, N. T., Wubshet, S. G., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Screening selected Vietnamese plants used to treat diabetes for PTP1B inhibitory activity

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  42. Published

    The α-glucosidase and PTP1B inhibitory effect of 45 medicinal plants extracts

    Liu, B., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  43. Published

    α-Glucosidase inhibitors from Phyllanthus amarus and Phyllanthus urinaria

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  44. 2017
  45. Published

    Advancing HPLC-PDA-HRMS-SPE-NMR analysis of coumarins in Coleonema album by use of orthogonal reversed-phase C18 and pentafluorophenyl separations

    Lima, R. D. C. L., Gramsbergen, S., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2017, In: Journal of Natural Products. 80, 4, p. 1020-1027

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

    Kannangara, R. M., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, Kenneth Thermann, Stærk, Dan, Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, Birger Lindberg, 2017, In: Nature Communications. 8, 12 p., 1987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Characterization of antileishmanial compounds from Lawsonia inermis leaves using semi-high resolution antileishmanial profiling combined with HPLC-HRMS-SPE-NMR

    Iqbal, K., Iqbal, J., Stærk, Dan & Kongstad, Kenneth Thermann, 2017, In: Frontiers in Pharmacology. 8, 7 p., 337.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.

    Silva, E. L. E., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, 2017, In: Fitoterapia. 118, p. 42-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Facilitated visual interpretation of scores in principal component analysis by bioactivity-labeling of 1H NMR spectra - metabolomics investigation and identification of a new α-glucosidase inhibitor in Radix Astragali

    Liu, Y., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 3, 12 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    High-resolution inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Vietnamese plants

    Trinh, T. D. B., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 7, 12 p., 1228.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Investigation of antidiabetic potential of Phyllanthus niruri L. using assays for α-glucosidase, muscle glucose transport, liver glucose production, and adipogenesis

    Beidokhti, M. N., Andersen, M. V., Eid, H. M., Villavicencio, M. L. S., Stærk, Dan, Haddad, P. S. & Jäger, A. K., 2017, In: Biochemical and Biophysical Research Communications. 493, 1, p. 869-874

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Isolation and structure elucidation of cyclopeptide alkaloids from Ziziphus nummularia and Ziziphus spina-christi by HPLC-DAD-MS and HPLC-PDA-HRMS-SPE-NMR

    Tuenter, E., Foubert, K., Stærk, Dan, Apers, S. & Pieters, L., 2017, In: Phytochemistry. 138, p. 163-169

    Research output: Contribution to journal › Journal article › Research › peer-review

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