David E. Gloriam

David E. Gloriam

Professor

ORCID: 0000-0002-4299-7561

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  1. Published

    Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABAA receptors

    Falk-Petersen, C. B., Tsonkov, T. M., Nielsen, M. S., Harpsøe, Kasper, Bundgaard, C., Frølund, Bente, Kristiansen, Uffe, Gloriam, David E. & Wellendorph, Petrine, 22 Jun 2020, In: Scientific Reports. 10, 1, 12 p., 10078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors

    Fidom, K., Isberg, V., Hauser, Alexander Sebastian, Mordalski, S., Lehto, T., Bojarski, A. J. & Gloriam, David E., Jan 2015, In: Methods. 71, p. 104-112 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Selectivity determinants of GPCR-G-protein binding

    Flock, T., Hauser, Alexander Sebastian, Lund, N., Gloriam, David E., Balaji, S. & Babu, M. M., 18 May 2017, In: Nature. 545, 7654, p. 317-322 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

    Foster, S. R., Hauser, Alexander Sebastian, Vedel, L., Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner, Hans & Gloriam, David E., 31 Oct 2019, In: Cell. 179, 4, p. 895-908

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

    Frandsen, I. O., Boesgaard, M. W., Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 4829.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives

    Fredriksson, R., Höglund, P. J., Gloriam, David E., Lagerström, M. C. & Schiöth, H. B., 20 Nov 2003, In: F E B S Letters. 554, 3, p. 381-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini

    Fredriksson, R., Gloriam, David E., Höglund, P. J., Lagerström, M. C. & Schiöth, H. B., 14 Feb 2003, In: Biochemical and Biophysical Research Communications. 301, 3, p. 725-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

    Gaiser, B. I., Danielsen, Mia, Marcher, Emil, Røpke Jørgensen, K., Wróbel, T. M., Frykman, M., Johansson, H., Bräuner, Hans, Gloriam, David E., Mathiesen, Jesper M. & Sejer Pedersen, D., 12 Sep 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 7806-7839 34 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A ligand's view of target similarity: chemogenomic binding site-directed techniques for drug discovery

    Garland, S. L. & Gloriam, David E., 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1872-1881

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Methods for the successful application of chemogenomics to GPCR drug design

    Garland, S. L. (ed.) & Gloriam, David E. (ed.), 2011, In: Current Topics in Medicinal Chemistry. 11, 15, p. 1870-1871

    Research output: Contribution to journal › Editorial › Research

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