David E. Gloriam
Professor
Pharmaceutical Informatics
Universitetsparken 2
2100 København Ø
- Published
Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139
Shehata, M. A., Jensen, A. C. N., Lissa, D., Bisig, C., Isberg, V., Andersen, K. B., Harpsøe, Kasper, Björkling, Fredrik, Bräuner, Hans & Gloriam, David E., 10 Nov 2016, In: Scientific Reports. 6, p. 1-13 13 p., 36681.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity
Sandhu, M., Cho, A., Ma, N., Mukhaleva, E., Namkung, Y., Lee, S., Ghosh, S., Lee, J. H., Gloriam, David E., Laporte, S. A., Babu, M. M. & Vaidehi, N., 2022, In: Nature Communications. 13, 1, 14 p., 7428.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SMARTCyp: A 2D method for prediction of cytochrome P450-mediated drug metabolism
Rydberg, P., Gloriam, David E., Zaretzki, J., Breneman, C. & Olsen, L., 15 Mar 2010, In: ACS Medicinal Chemistry Letters. 1, 3, p. 96-100Research output: Contribution to journal › Letter › Research › peer-review
- Published
SMARTCyp web service
Rydberg, P., Gloriam, David E. & Olsen, L., 2010Research output: Non-textual form › Interactive production › Research
- Published
The contribution of atom accessibility to site of metabolism models for cytochromes P450
Rydberg, P., Rostkowski, M., Gloriam, David E. & Olsen, L., 1 Apr 2013, In: Molecular Pharmaceutics. 10, 4, p. 1216-1223 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SMARTCyp cytochrome P450 metabolism prediction server
Rydberg, P., Gloriam, David E. & Olsen, L., 1 Dec 2010, In: Bioinformatics. 26, 23, p. 2988-2989Research output: Contribution to journal › Letter › Research › peer-review
- Published
Structural Determinants for the Mode of Action of Imidazopyridine DS2 at δ-Containing γ-Aminobutyric Acid Type A Receptors
Rostrup, F., Falk-petersen, C. B., Harpsøe, Kasper, Buchleithner, S., Conforti, I., Jung, S., Gloriam, David E., Schirmeister, T., Wellendorph, Petrine & Frølund, Bente, 22 Apr 2021, In: Journal of Medicinal Chemistry. 64, 8, p. 4730-4743 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPCRmd uncovers the dynamics of the 3D-GPCRome
Rodríguez-Espigares, I., Torrens-Fontanals, M., Tiemann, J. K. S., Aranda-García, D., Ramírez-Anguita, J. M., Stepniewski, T. M., Worp, N., Varela-Rial, A., Morales-Pastor, A., Medel-Lacruz, B., Pándy-Szekeres, G., Mayol, E., Giorgino, T., Carlsson, J., Deupi, X., Filipek, S., Filizola, M., Gómez-Tamayo, J. C., Gonzalez, A., Gutiérrez-de-Terán, H. & 27 others, , 2020, In: Nature Methods. 17, 8, p. 777-787Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Differential G protein activation by the long and short isoforms of the dopamine D2 receptor
Reiner-Link, David, Madsen, Jakob Sture, Gloriam, David E., Bräuner, Hans & Hauser, Alexander Sebastian, 2024, (Accepted/In press) In: British Journal of Pharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPCRdb in 2018: adding GPCR structure models and ligands
Pándy-Szekeres, Gáspár, Munk, C., Tsonkov, T. M., Mordalski, S., Harpsøe, Kasper, Hauser, Alexander Sebastian, Bojarski, A. J. & Gloriam, David E., 2018, In: Nucleic Acids Research. 46, D1, 7 p., gkx1109.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5953796
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Kemogenomik: Receptoren set fra lægemiddelstoffets synspunkt
Research output: Contribution to journal › Journal article › Research
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926
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Generic GPCR residue numbers - aligning topology maps while minding the gaps
Research output: Contribution to journal › Journal article › Research › peer-review
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561
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Pharmacogenomics of GPCR Drug Targets
Research output: Contribution to journal › Journal article › Research › peer-review
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