Henrik Franzyk
Associate Professor
Iridoid Glucosides from Phlomis tuberosa L. and Phlomis herba-ventis L
Alipieva, K. I., Jensen, S. R., Franzyk, Henrik, Handjieva, N. V. & Evstatieva, L. N., 2000, In: Zeitschrift für Naturforschung C - A Journal of Biosciences. 55c, p. 137-140 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the nanostructure of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles
Aljabbari, Anas Samir Mohammad, Lokras, Abhijeet, Kirkensgaard, Jacob Judas Kain, Rades, Thomas, Franzyk, Henrik, Thakur, A., Zhang, Y. & Foged, Camilla, 2023, In: Journal of Colloid and Interface Science. 633, p. 907-922Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-locked analogs of the antimicrobial peptide BP214
Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.Research output: Contribution to journal › Journal article › Research › peer-review
- Submitted
Anchoring of hydrophilic coating polymers onto charged liposomes via attractive electrostatic interactions using charged tags to control the surface charge drainage properties and cellular targeting
Andersen, P. L., Christensen, D., Franzyk, Henrik, Foged, Camilla & Schmidt, S. T., 2018, (Submitted)Research output: Patent
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Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections
Bahnsen, J. S., Franzyk, Henrik, Sayers, E. J., Jones, A. T. & Nielsen, Hanne Mørck, 2015, In: Pharmaceutical Research. 32, 5, p. 1546-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The antimicrobial and cell-penetrating effects of the CPP penetratin and derived analogues.
Bahnsen, J. S., Franzyk, Henrik & Nielsen, Hanne Mørck, 2012.Research output: Contribution to conference › Poster › Research
- Published
Håb om at ramme latente bakterier i deres skjul
Bahnsen, J. S., Water, J. J., Foged, Camilla, Franzyk, Henrik & Nielsen, Hanne Mørck, 2012, In: Lægemiddelforskning 2012. 2012, p. 12-14Research output: Contribution to journal › Journal article › Research
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Cell-penetrating Peptides Targeting Intracellular Infections
Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013.Research output: Contribution to conference › Poster › Research › peer-review
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Antimicrobial and cell-penetrating properties of penetratin analogs: effect of sequence and secondary structure
Bahnsen, J. S., Franzyk, Henrik, Sandberg-Schaal, A. & Nielsen, Hanne Mørck, 2013, In: B B A - Biomembranes. 1828, 2, p. 223-232 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Baker, K. R., Jana, B., Hansen, A. M., Vissing, K. J., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2019, In: International Journal of Antimicrobial Agents. 53, p. 868-872 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics
Baker, K. R., Jana, B., Hansen, A. M., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2 Jul 2019, In: Frontiers in Cellular and Infection Microbiology. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high-throughput approach to identify compounds that impair envelope integrity in Escherichia coli
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, Oct 2016, In: Antimicrobial Agents and Chemotherapy. 60, 10, p. 5995-6002 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An approach to identify clinically relevan, non-toxic peptide-antimicrobial combinations that eliminate intrinsic resistance in Gram-negative pathogens
Baker, K. R., Jana, B., Nielsen, Hanne Mørck, Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Synergistic peptidomimetic-antimicrobial combinations to combat multidrug-resistant Gram-negative bacterial infections
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2017. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Breaching bacterial barricades: A high-throughput approach to identify compounds targeting envelope integrity
Baker, K. R., Jana, B., Franzyk, Henrik & Guardabassi, Luca, 2016. 1 p.Research output: Contribution to conference › Poster › Research
- Published
The agr inhibitors solonamide B and analogues alter immune responses to Staphylococccus aureus but do not exhibit adverse effects on immune cell functions
Baldry, M., Kitir, B., Frøkiær, Hanne, Christensen, S. B., Taverne, N., Meijerink, M., Franzyk, Henrik, Olsen, Christian Adam, Wells, J. M. & Ingmer, Hanne, 2016, In: P L o S One. 11, 1, 17 p., e0145618.Research output: Contribution to journal › Journal article › Research › peer-review
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Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin
Birch, D., Sayers, E. J., Christensen, M. V., Jones, A. T., Franzyk, Henrik & Nielsen, Hanne Mørck, 2023, In: Pharmaceutics. 15, 6, 15 p., 1672.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Stereochemistry as a determining factor for the effect of a cell-penetrating peptide on cellular viability and epithelial integrity
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 24 May 2018, In: Biochemical Journal. 475, 10, p. 1773-1788 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intact penetratin metabolite permeates across Caco-2 monolayers
Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2015.Research output: Contribution to conference › Poster › Research
- Published
Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclopentanoid cyanohydrin glucosides from Passiflora mixta
Bylov, T., Franzyk, Henrik & Jaroszewski, J. W., 2004, In: Biochemical Systematics and Ecology. 32, p. 695-698 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR
Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182Research output: Contribution to journal › Journal article › Research › peer-review
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On-resin N-formylation of peptides: a head-to-head comparison of reagents in solid-phase synthesis of ligands for formyl peptide receptors
Christensen, S. B., Hansen, A. M. & Franzyk, Henrik, 2017, In: Journal of Peptide Science. 23, 5, p. 410-415 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy
Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768Research output: Contribution to journal › Journal article › Research
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Improved in vitro evaluation of novel antimicrobials: potential synergy between human plasma and antibacterial peptidomimetics, AMPs, or antibiotics against human pathogenic bacteria
Citterio, L., Franzyk, Henrik, Palarasah, Y., Andersen, T. E., Mateiu, R. V. & Gram, L., Feb 2016, In: Research in Microbiology. 167, 2, p. 72-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human plasma potentiates antibacterial effect of peptidomimetics against Gram-negative and Gram-positive pathogenic bacteria
Citterio, L., A, K., K, H., Franzyk, Henrik & Gram, L., 2014.Research output: Contribution to conference › Poster › Research
- Published
Solid-phase route to Fmoc-protected cationic amino acid building blocks
Clausen, J. D., Linderoth, L., Nielsen, Hanne Mørck & Franzyk, Henrik, 2012, In: Amino Acids. 43, 4, p. 1633-41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of antibacterial activity (in vitro and in vivo) and mode of action for des-acyl tridecaptins (DATs)
Couturier, C., Ronzon, Q., Lattanzi, G., Lingard, I., Coyne, S., Cazals, V., Dubarry, N., Yvon, S., Leroi-Geissler, C., Gracia, O. R., Teague, J., Sordello, S., Corbett, D., Bauch, C., Monlong, C., Payne, L., Taillier, T., Fuchs, H., Broenstrup, M., Harrison, P. H. & 10 others, , 2024, In: European Journal of Medicinal Chemistry. 265, 20 p., 116097.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-assisted ring-opening of activated aziridines with resin-bound amines
Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan, Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Journal of Organic Chemistry. 73, 9, p. 3566-3569 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expedite Protocol for Construction of Chiral Regioselectively N-Protected Monosubstituted Piperazine, 1,4-Diazepane, and 1,4-Diazocane Building Blocks
Crestey, F., Witt, M., Jaroszewski, J. W. & Franzyk, Henrik, 11 Jun 2009, In: Journal of Organic Chemistry. 74, 15, p. 5652-5655Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient loading of primary alcohols onto a solid phase using a trityl bromide linker
Crestey, F., Ottesen, L. K., Jaroszewski, J. W. & Franzyk, Henrik, 2008, In: Tetrahedron Letters. 49, 41, p. 5890-5893Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies towards improved cell-penetrating peptide-promoted macromolecular drug delivery
Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Drug Discovery Today. 15, 23-24, p. 1109 1 p., A81.Research output: Contribution to journal › Conference abstract in journal › Research
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Studies towards improved stability and permeability of a cell-penetrating peptide
Dahlqvist Clausen, J. A., Linderoth, L., Andersen, R. B., Franzyk, Henrik & Nielsen, Hanne Mørck, 2010, In: Journal of Peptide Science. 16, p. 148 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Fontanesioside and 5-Hydroxysecologanol from Fontanesia phillyreoides.
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 35, p. 705-711 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Syringa and Fraxinus: Secoiridoid Precursors
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 773-784 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Syringa and Fraxinus: Carbocyclic Iridoid Precursors
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1995, In: Phytochemistry. 40, p. 785-792 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Iridoids in Forsythia spp.
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 37, p. 173-178 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Secoiridoids in Fontanesia
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1994, In: Phytochemistry. 38, p. 615-621 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iridoid Glucosides from Picconia excelsa
Damtoft, S., Franzyk, Henrik & Jensen, S. R., 1997, In: Phytochemistry. 45, p. 743-750 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Factors of Importance for Spray Drying of Small Interfering RNA-Loaded Lipidoid-Polymer Hybrid Nanoparticles for Inhalation
Dormenval, C., Lokras, Abhijeet, Cano-Garcia, G., Wadhwa, A., Thanki, K., Rose, F., Thakur, A., Franzyk, Henrik & Foged, Camilla, 2019, In: Pharmaceutical Research. 36, 10, 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Characterisation of an Array of Lipidoid Analogues for RNA Interference Therapy
Falkenberg, E., de Groot, A. M., Sijts, A. J. A. M., Thanki, K., Zeng, X., Nielsen, Hanne Mørck, Franzyk, Henrik & Foged, Camilla, 2017.Research output: Contribution to conference › Poster › Research
- Published
Philanthotoxin-343 attenuates retinal and optic nerve injury, and protects visual function in rats with N-methyl-D-aspartate-induced excitotoxicity
Fazel, M. F., Abu, I. F., Mohamad, M. H. N., Agarwal, R., Iezhitsa, I., Bakar, N. S., Juliana, N., Mellor, I. R. & Franzyk, Henrik, 2020, In: PLoS ONE. 15, 7, 14 p., e0236450.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanoparticle compositions comprising PLGA derivatives and a lipid for delivery of drugs, in particular nucleic acids, especially siRNA
Foged, Camilla, Franzyk, Henrik, Zeng, X., Nielsen, Hanne Mørck & Thanki, K., 21 Sep 2017, IPC No. A61K31/713, A61K47/18, A61K47/34, A61K9/51, A61P25/00, A61P29/00, A61P35/00, Patent No. WO2017158093-A1, 16 Mar 2017, Priority date 17 Mar 2016, Priority No. EP 2016-160931Research output: Patent
- Published
Cellular uptake and membrane-destabilising properties of a-peptide/ß-peptoid chimeras: lessons for the design of new cell-penetrating peptides
Foged, Camilla, Franzyk, Henrik, Bahrami, S., Frøkjær, Sven, Jaroszewski, J. W., Nielsen, Hanne Mørck & Olsen, Christian Adam, 2008, In: BBA General Subjects. 1778, 11, p. 2487-2495Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-Assisted Ring-Opening of Activated Aziridines with Resin-Bound Amines
Franzyk, Henrik, Crestey, F., Witt, M., Frydenvang, Karla Andrea, Stærk, Dan & Jaroszewski, J., 2008, In: Synfacts. 7, p. 769Research output: Contribution to journal › Journal article › Research › peer-review
Constrained Glycopeptide Ligands for MPRs. Limitations of Unprotected Phosphorylated Building Blocks
Franzyk, Henrik, Christensen, M. K., Jørgensen, R. M., Meldal, M., Cordes, H., Mouritsen, S. & Bock, K., 1997, In: Bioorganic and Medicinal Chemistry. 5, p. 21-40 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
Halohydrins and Polyols Derived from Antirrhinoside: Structural Revision of Muralioside and Epimuralioside
Franzyk, Henrik, Jensen, S. R., Thale, Z. & Olsen, C. E., 1999, In: Journal of Natural Products. 62, p. 275-278 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis of aliphatic O-dimannosyl amino acid building blocks for solid-phase assembly of glycopeptide libraries
Franzyk, Henrik, Meldal, M., Paulsen, H. & Bock, K., 1995, In: Journal of the Chemical Society, Perkin Transactions 1. 36, 9, p. 2883-2898 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Excelsioside, a Secoiridoid Glucoside from Fraxinus excelsior L.
Damtoft, S., Franzyk, H. & Jensen, S. R., D. S. ,. F. H. &. J. S. R., 1992, In: Phytochemistry. 31, p. 4197-4201Research output: Contribution to journal › Journal article › Research › peer-review
Iridoid Glucosides from Penstemon secundiflorus and P. grandiflorus: Revised Structure of 10-hydroxy-8-epihastatoside
Franzyk, Henrik, Stermitz, F. R. & Jensen, S. R., 1998, In: Phytochemistry. 49, p. 2025-2030 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Jagten på kongens efterfølger
Franzyk, Henrik, Björkling, Fredrik, Nielsen, J. & Nielsen, Peter E., 2015, In: Lægemiddelforskning. 2015, p. 24-27 4 p.Research output: Contribution to journal › Journal article › Communication
- Published
A 9-Hydroxyiridoid Isolated from Junellia seriphioides (Verbenaceae)
Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Quiroga, J. M., 2000, In: Organic Letters. 2, p. 699-700 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis of Antirrhinolide, a New Lactone fromAntirrhinum Majus
Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., Aug 1998, In: European Journal of Organic Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Noter til bioorganisk kemi M23-1
Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.Research output: Book/Report › Compendium/lecture notes › Education
- Published
SYNTHESIS OF NOVEL HYDROXYMETHYL SUBSTITUTED ANALOGUES RELATED TO CARBOVIR AND NEPLANOCIN A
Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Rasmussena, J. H., Apr 2002, In: Nucleosides, Nucleotides and Nucleic Acids.Research output: Contribution to journal › Journal article › Research › peer-review
Glycopeptide Mimics of Mammalian Man9GlcNAc2. Ligand Binding to Mannan Binding Proteins (MBPs)
Franzyk, Henrik, Meldal, M., Paulsen, H., Thiel, S., Jensenius, J. C. & Bock, K., 1996, In: Bioorganic and Medicinal Chemistry. 4, p. 1881-1899 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mini-manual: Søgninger i Reaxys
Franzyk, Henrik, 2018, 4 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Fastfase-syntese af Peptider - en visuel guide
Franzyk, Henrik, 2018, 18 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Guide til Rapportskrivning i Kurset Biopharmaceuticals: Bioorganisk Kemi 2018
Franzyk, Henrik, 2018, 17 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Iridoid Glucosides from Myxopyrum s milacifolium
Franzyk, Henrik, Jensen, S. R. & Olsen, C. E., May 2001, In: Journal of Natural Products.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of novel hydroxymethyl substituted analogues related to carbovir and neplanocin A
Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Rasmussen, J. H., 2002, In: Nucleosides, Nucleotides and Nucleic Acids. 21, 1, p. 23-43 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of Monoterpene Piperidines from the Iridoid Glucoside Antirrhinoside
Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 1997, In: Journal of Natural Products. 60, p. 1012-1016 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A caffeoyl phenylethanoid glycoside from plantago myosuros
Franzyk, Henrik, Husum, T. L. & Jensen, S. R., 1998, In: Phytochemistry. 47, 6, p. 1161-1162 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A 9-Hydroxyiridoid Isolated fromJunellia seriphioides(Verbenaceae)
Franzyk, Henrik, Jensen, S. R., Olsen, C. E. & Quiroga, J. M., Mar 2000, In: Organic Letters.Research output: Contribution to journal › Journal article › Research › peer-review
Conversion of the iridoid glucoside antirrhinoside into 3-azabicyclo[3.3.0]octane building blocks
Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 2000, In: Journal of Natural Products. 63, 5, p. 592-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Biosynthesis of Secoiridoid Glucosides in Oleaceae
Damtoft, S., Franzyk, H. & Jensen, S. R., D. S. ,. F. H. &. J. S. R., 1993, In: Phytochemistry. 34, p. 1291-1299Research output: Contribution to journal › Journal article › Research › peer-review
Iridoid glucosides from Myxopyrum smilacifolium
Franzyk, Henrik, Jensen, S. R. & Olsen, C. E., 2001, In: Journal of Natural Products. 64, 5, p. 632-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting Toxins toward Tumors
Franzyk, Henrik & Christensen, Søren Brøgger, 2021, In: Molecules. 26, 5, 23 p., 1292.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis of Antirrhinolide, a New Lactone from Antirrhinum majus
Franzyk, Henrik, Frederiksen, S. M. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 1665-1667 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dopaol 2-keto- and 2,3-diketoglycosides from Chelone obliqua
Franzyk, Henrik, Olsen, C. E. & Jensen, Søren, 2004, In: Journal of Natural Products. 67, 6, p. 1052-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On-Resin Carboxy Group Activation of ω-Amino Acids in Solid-Phase Synthesis of Philanthotoxin Analogues
Franzyk, Henrik, Jørgensen, M. R., Jaroszewski, J. W. & Witt, M., 2005, In: Synthesis.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition
Franzyk, Henrik, Grzeskowiak, J. W., Tikhonov, D. B., Jaroszewski, J. W. & Mellor, I. R., Aug 2014, In: ChemMedChem. 9, 8, p. 1725-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Investigation of the Biosynthesis of Secoiridoid Glucosides in the Olive Family: Dept. Organic Chemistry, Technical University of Denmark
Franzyk, Henrik, 4 Nov 1993Research output: Book/Report › Ph.D. thesis › Research
- Published
Øvelsesvejledning til bioorganisk kemi: øvelser M23-2
Franzyk, Henrik, 2007, Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.Research output: Book/Report › Compendium/lecture notes › Education
Iridoids and Verbascosides in Retzia
Damtoft, S., Franzyk, H., Jensen, S. R. & Nielsen B.J., D. S. ,. F. H. ,. J. S. R. &. N. B. J., 1993, In: Phytochemistry. 34, p. 239-243Research output: Contribution to journal › Journal article › Research › peer-review
Synthetic aspects of iridoid chemistry
Franzyk, Henrik, 2000, In: Fortschritte der Chemie Organischer Naturstoffe. 79, p. 1-114 114 p.Research output: Contribution to journal › Review › Research
Synthesis of Carbocyclic Homo-N-nucleosides from Iridoids
Franzyk, Henrik, Rasmussen, J. H., Mazzei, R. A. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 2931-2935 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Noter til BIOPHARMACEUTICALS: BIOORGANISK KEMI
Franzyk, Henrik & Nielsen, Peter E., 15 Aug 2016, Dept. Drug Design and Pharmacology. 159 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Biopolymer-based nanogels improve the safety profile and antimicrobial activity of a lysine-based peptidomimetic.
Franzyk, Henrik, 2017.Research output: Contribution to conference › Poster › Research › peer-review
Ozonolysis of Protected Iridoid Glucosides
Franzyk, Henrik, Rasmussen, J. H. & Jensen, S. R., 1998, In: European Journal of Organic Chemistry. p. 365-370 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stereoselective Hydrogenation and Ozonolysis of Iridoids. Conversion into Carbocyclic Nucleoside Analogues
Franzyk, Henrik & Stermitz, F. R., 1999, In: Journal of Natural Products. 62, p. 1646-1654 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ØVELSESVEJLEDNING TIL: Øvelsesdelen af Biopharmaceuticals: Bioorganisk Kemi
Franzyk, Henrik, 15 Aug 2016, Dept. Drug Design and Pharmacology. 60 p.Research output: Book/Report › Compendium/lecture notes › Education
- Published
Vejledning til Praktisk Udførelse af Øvelsesdelen i Kurset Biopharmaceuticals: Bioorganisk Kemi 2018
Franzyk, Henrik, 2018, 66 p.Research output: Book/Report › Compendium/lecture notes › Education
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Peptide/β-Peptoid Hybrids with Ultrashort PEG-Like Moieties: Effects on Hydrophobicity, Antibacterial Activity and Hemolytic Properties
Frederiksen, N., Louka, S., Mudaliar, C., Domraceva, I., Kreicberga, A., Pugovics, O., Żabicka, D., Tomczak, M., Wygoda, W., Björkling, Fredrik & Franzyk, Henrik, 2021, In: International Journal of Molecular Sciences. 22, 13, 17 p., 7041.Research output: Contribution to journal › Journal article › Research › peer-review
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Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity
Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561Research output: Contribution to journal › Journal article › Research › peer-review
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Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity
Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-Activity Study of alpha-Peptoid/alpha-Peptide Peptidomimetics: Influence of Hydrophobicity on Antimicrobial Activity and Cytotoxicity
Frederiksen, N., Bjorkling, F., Nielsen, P. & Franzyk, Henrik, Sep 2018, In: Journal of Peptide Science. 24, s2, p. S120-S120Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists
Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451Research output: Contribution to journal › Journal article › Research › peer-review
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Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors
Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.Research output: Contribution to conference › Poster › Research
- Published
Highly cationic cell-penetrating peptides affect the barrier integrity and facilitates mannitol permeation in a human stem cell-based blood-brain barrier model
Frøslev, Patrick, Franzyk, Henrik, Ozgür, Burak, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: European Journal of Pharmaceutical Sciences. 168, 10 p., 106054.Research output: Contribution to journal › Journal article › Research › peer-review
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Facile Preparation of PNA-Peptide Conjugates with a Polar Maleimide-Thioether Linkage
Hansen, A. M., Shaikh, Ashif Yasin & Franzyk, Henrik, 2020, Peptide Nucleic Acids: Methods and Protocols. P. E. N. (ed.). Humana Press, p. 97-118 22 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2105).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae
Hansen, A. M., Bonke, G., Hogendorf, W. F. J., Björkling, Fredrik, Nielsen, J., Kongstad, Kenneth Thermann, Zabicka, D., Tomczak, M., Urbas, M., Nielsen, Peter E. & Franzyk, Henrik, 2019, In: European Journal of Medicinal Chemistry. 168, p. 134-145 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists
Hansen, A. M., Peng, P., Baldry, M., Perez-Gassol, I., Christensen, S. B., Vinther, J. M., Ingmer, Hanne & Franzyk, Henrik, 2018, In: European Journal of Medicinal Chemistry. 152, p. 370-376 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibacterial Peptide Nucleic Acid-Antimicrobial Peptide (PNA-AMP) Conjugates: Antisense Targeting of Fatty Acid Biosynthesis
Hansen, A. M., Bonke, G., Larsen, C. J., Yavari, Niloofar, Nielsen, Peter E. & Franzyk, Henrik, 2016, In: Bioconjugate Chemistry. 27, 4, p. 863-867 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies on acid stability and solid-phase block synthesis of peptide-peptoid hybrids: ligands for formyl peptide receptors
Hansen, A. M., Skovbakke, S. L., Christensen, S. B., Perez-Gassol, I. & Franzyk, Henrik, 2019, In: Amino Acids. 51, p. 205-218Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrophage phosphoproteome analysis reveals MINCLE-dependent and -independent mycobacterial cord factor signaling
Hansen, M., Peltier, J., Killy, B., Amin, B., Bodendorfer, B., Härtlova, A., Uebel, S., Bosmann, M., Hofmann, J., Büttner, C., Ekici, A. B., Kuttke, M., Franzyk, Henrik, Foged, Camilla, Beer-Hammer, S., Schabbauer, G., Trost, M. & Lang, R., Apr 2019, In: Molecular and Cellular Proteomics. 18, 4, p. 669-685Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorophore labeling of a cell-penetrating peptide significantly alters the mode and degree of biomembrane interaction
Hedegaard, S. F., Derbas, M. S., Lind, T. K., Kasimova, M. R., Christensen, M. V., Michaelsen, M. H., Campbell, R. A., Jørgensen, Lene, Franzyk, Henrik, Cárdenas, M. & Nielsen, Hanne Mørck, 2018, In: Scientific Reports. 8, 1, 14 p., 6327.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selectivity in the potentiation of antibacterial activity of α-peptide/β-peptoid peptidomimetics and antimicrobial peptides by human blood plasma
Hein-Kristensen, L., Knapp, K. M., Franzyk, Henrik & Gram, L., 27 Aug 2013, In: Research in Microbiology. 164, 9, p. 933-940 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302063
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1999
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Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues
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Prolonged Shelf Life in Fermented Milk Products Investigated by Bioassay-Guided Chemometrics
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Non-natural Amino Acid and Peptoid Building Blocks for Optimization of the Cell-Penetrating (R-X-R)n Motif
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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