Jesper Langgaard Kristensen
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
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(11)C-labeling and preliminary evaluation of pimavanserin as a 5-HT2A receptor PET-radioligand
Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Dyssegaard, A., Knudsen, G. M. & Kristensen, Jesper Langgaard, 20 Jan 2015, In: Bioorganic & Medicinal Chemistry Letters. 25, 5, p. 1053–1056 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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(11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand
Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 19 Apr 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-2411 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands
Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, Anders A., Gillings, N., Lehel, S., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, Apr 2017, In: Organic & Biomolecular Chemistry. 15, p. 4351-4358Research output: Contribution to journal › Journal article › Research › peer-review
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25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor
Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270Research output: Contribution to journal › Review › Research › peer-review
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5-HT2A/5-HT2C receptor pharmacology and intrinsic clearance of N-benzylphenethylamines modified at the primary site of metabolism
Leth-Petersen, S., Petersen, I. N., Jensen, Anders A., Bundgaard, C., Bæk, M., Kehler, J. & Kristensen, Jesper Langgaard, 26 Aug 2016, In: A C S Chemical Neuroscience. p. 1-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Prodrug Approach Involving In Situ Depot Formation to Achieve Localized and Sustained Action of Diclofenac After Joint Injection
Thing, M., Agårdh, L., Larsen, Susan Weng, Rasmussen, R., Pallesen, J., Mertz, N., Kristensen, Jesper Langgaard, Hansen, M., Østergaard, Jesper & Larsen, C. S., 2014, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4021–4029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A quantitative method for the selective 5-HT2A agonist 25CN-NBOH in rat plasma and brain
Breusova, K., Ernstsen, K. G., Palner, M., Linnet, Kristian, Kristensen, Jesper Langgaard & Kretschmann, A. C., 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114016.Research output: Contribution to journal › Journal article › Research › peer-review
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A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE
Jepsen, T. H., Glibstrup, E., Crestey, F. L. J., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2017, In: Beilstein Journal of Organic Chemistry. 13, p. 988-994 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accelerating preclinical PET-screening: reductive amination with [11C]methoxybenzaldehydes
Herth, Matthias Manfred, Leth-Petersen, S., Lehel, S., Hansen, M., Gillings, N., Madsen, J. & Kristensen, Jesper Langgaard, 2014, In: R S C Advances. 41, p. 21347-21350 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amination of aryl iodides using a fluorous-tagged ammonia equivalent
Nielsen, S. D., Smith, G., Begtrup, M. & Kristensen, Jesper Langgaard, 2010, In: European Journal of Organic Chemistry. 2010, 19, p. 3704-3710Research output: Contribution to journal › Journal article › Research › peer-review
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Aminolysis of resin-bound N-nosylaziridine-2-carboxylic acids
Olsen, Christian Adam, Christensen, C., Nielsen, Birgitte, Farah, M. M., Mohamed, F. M., Witt, M., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Organic Letters. 8, 15, p. 3371-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An Improved Radiolabelling Strategy for the 5-HT2A Agonist, [C-11]Cimbi-36
Gillings, N., Lehel, S., Herth, Matthias Manfred, Leth-Petersen, S., Madsen, J., Gabel-Jensen, C. & Kristensen, Jesper Langgaard, 15 May 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, p. S296-S296 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH
Marcher, Emil, Nykodemova, J. & Kristensen, Jesper Langgaard, 2021, In: SynOpen. 5, 2, p. 158-160Research output: Contribution to journal › Journal article › Research › peer-review
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Animal Behavior in Psychedelic Research
Odland, Anna Ulstein, Kristensen, Jesper Langgaard & Andreasen T., Jesper, 2022, In: Pharmacological Reviews. 74, 4, p. 1176-1205 30 p.Research output: Contribution to journal › Review › Research › peer-review
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Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH
Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, Jesper Langgaard, Olsen, L. & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 5, p. 671–679Research output: Contribution to journal › Journal article › Research › peer-review
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Computational Methods to Predict the Regioselectivity of Electrophilic Aromatic Substitution Reactions of Heteroaromatic Systems
Kruszyk, M., Jessing, M., Kristensen, Jesper Langgaard & Jorgensen, M., 13 May 2016, In: Journal of Organic Chemistry. 81, 12, p. 5128–5134 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Concise synthesis of new bridged-nicotine analogues
Crestey, F., Hooyberghs, G. & Kristensen, Jesper Langgaard, 4 Feb 2012, In: Tetrahedron. 68, 5, p. 1417-1421Research output: Contribution to journal › Journal article › Research › peer-review
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Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases
Knuhtsen, A., Legrand, B., Van der Poorten, O., Amblard, M., Martinez, J., Ballet, S., Kristensen, Jesper Langgaard & Pedersen, D. S., 12 Aug 2016, In: Chemistry: A European Journal. 22, 39, p. 14022–14028 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction
Stéen, E. J. L., Shalgunov, Vladimir, Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 2019, In: European Journal of Organic Chemistry. 2019, 8, p. 1722-1725Research output: Contribution to journal › Journal article › Research › peer-review
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Convenient access to F-18-labeled amines through the Staudinger reduction
Shalgunov, Vladimir, Steen, J., Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supl. 1/SI, p. S205-S206 P-050.Research output: Contribution to journal › Conference abstract in journal › Research
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Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands
Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, Anders A., Lehel, S., Gillings, N., Herth, Matthias Manfred, Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Bioorganic & Medicinal Chemistry. 24, p. 5353-5356 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Convergent synthesis of 3-arylated 1-hydroxypyrazoles via 3-metalated pyrazole-1-oxides
Eskildsen, J., Kristensen, Jesper Langgaard, Vedsø, P., Begtrup, M. & Kristensen, Jesper Langgaard, 14 Dec 2001, In: Journal of Organic Chemistry. 66, 25, p. 8654-8656 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Convergent synthesis of 6-substituted phenanthridines via anionic ring closure
Lysén, M., Kristensen, Jesper Langgaard, Vedsø, P. & Begtrup, M., 1 Jan 2002, In: Organic Letters. 4, 2, p. 257-259 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Correlating the Metabolic Stability of Psychedelic 5-HT2A Agonists with Anecdotal Reports of Human Oral Bioavailability
Leth-Petersen, S., Bundgaard, C., Hansen, M., Carnerup, M. A., Kehler, J. & Kristensen, Jesper Langgaard, 12 Feb 2014, In: Neurochemical Research. 39, 10, p. 2018-2023 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cover Feature: Convenient Entry to 18 F-Labeled Amines through the Staudinger Reduction (Eur. J. Org. Chem. 8/2019)
Stéen, E. J. L., Shalgunov, Vladimir, Denk, C., Mikula, H., Kjær, Andreas, Kristensen, Jesper Langgaard & Herth, Matthias Manfred, 28 Feb 2019, In: European Journal of Organic Chemistry. 2019, 8, p. 1686-1686Research output: Contribution to journal › Journal article › Communication
ID: 1305029
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Convenient access to F-18-labeled amines through the Staudinger reduction
Research output: Contribution to journal › Conference abstract in journal › Research
Published -
331
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A strategic approach to [6,6]-bicyclic lactones: application towards the CD fragment of DHβE
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
223
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Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C
Research output: Contribution to journal › Journal article › Research › peer-review
Published