An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH
Research output: Contribution to journal › Journal article › Research › peer-review
Documents
- Fulltext
Final published version, 315 KB, PDF document
4-{2-[(2-hydroxybenzyl)amino]ethyl}-2,5-dimethoxybenzonitrile (25CN-NBOH) was first reported as a potent and highly selective serotonin 2A receptor (5-HT2AR) agonist in 2014. The compound has since found extensive use as a pharmacological tool in a variety of in vivo and in vitro studies. In the present study, we present an improved and scalable synthesis of 25CN-NBOH making this compound readily available to the scientific community.
Original language | English |
---|---|
Journal | SynOpen |
Volume | 5 |
Issue number | 2 |
Pages (from-to) | 158-160 |
DOIs | |
Publication status | Published - 2021 |
Number of downloads are based on statistics from Google Scholar and www.ku.dk
No data available
ID: 272425188