Jesper Langgaard Kristensen

Jesper Langgaard Kristensen

Professor

ORCID: 0000-0002-5613-1267

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  1. Published

    Medicindepot dannes efter injektion i leddet

    Larsen, Susan Weng, Thing, M. A., Østergaard, Jesper, Kristensen, Jesper Langgaard, Hansen, M. & Larsen, C. S., 2013, In: Lægemiddelforskning. 2013, p. 38-40

    Research output: Contribution to journal › Journal article › Research

  2. Published

    Metabolic fate of hallucinogenic NBOMes

    Leth-Petersen, S., Gabel-Jensen, C., Gillings, N., Lehel, S., Hansen, H. D., Knudsen, G. M. & Kristensen, Jesper Langgaard, 2016, In: Chemical Research in Toxicology. 29, 1, p. 96–100 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    5-HT2A/5-HT2C receptor pharmacology and intrinsic clearance of N-benzylphenethylamines modified at the primary site of metabolism

    Leth-Petersen, S., Petersen, I. N., Jensen, Anders A., Bundgaard, C., Bæk, M., Kehler, J. & Kristensen, Jesper Langgaard, 26 Aug 2016, In: A C S Chemical Neuroscience. p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Correlating the Metabolic Stability of Psychedelic 5-HT2A Agonists with Anecdotal Reports of Human Oral Bioavailability

    Leth-Petersen, S., Bundgaard, C., Hansen, M., Carnerup, M. A., Kehler, J. & Kristensen, Jesper Langgaard, 12 Feb 2014, In: Neurochemical Research. 39, 10, p. 2018-2023 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)

    Leurs, U., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Lohse, B., 15 Sep 2012, In: Bioorganic & Medicinal Chemistry Letters. 22, 18, p. 5811-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry

    Leurs, U., Lohse, B., Ming, S. A., Cole, P. A., Clausen, Rasmus Prætorius, Kristensen, Jesper Langgaard & Rand, Kasper Dyrberg, 17 Oct 2014, In: Analytical Chemistry. 86, 23, p. 11734-11741 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

    Leurs, U., Lohse, B., Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In: A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

    Lohse, B., Helgstrand, C., Andersson, J. L., Leurs, U., Cloos, P. A. C., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 2 Jul 2013, In: P L o S One. 8, 7, p. e67653

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Inhibitors of histone demethylases

    Lohse, B., Kristensen, Jesper Langgaard, Kristensen, L. H., Agger, K., Helin, K., Gajhede, Michael & Clausen, Rasmus Prætorius, 1 Feb 2011, In: Bioorganic & Medicinal Chemistry. 19, 12, p. 3625-3636 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

    Lohse, B., Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, P. A. C., Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In: Angewandte Chemie International Edition. 50, 39, p. 9100-9103

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Synthesis of tertiary benzamides via Pd-catalyzed coupling of arylboronic esters and carbamoyl chlorides

    Lysén, M., Kelleher, S., Begtrup, M. & Kristensen, Jesper Langgaard, 24 Jun 2005, In: Journal of Organic Chemistry. 70, 13, p. 5342-5343 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Convergent synthesis of 6-substituted phenanthridines via anionic ring closure

    Lysén, M., Kristensen, Jesper Langgaard, Vedsø, P. & Begtrup, M., 1 Jan 2002, In: Organic Letters. 4, 2, p. 257-259 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Synthesis, cross-coupling, and anionic cyclization of ortho-substituted naphthaleneboronic esters

    Lysén, M., Madden, M., Kristensen, Jesper Langgaard, Vedsø, P., Zöllner, C. & Begtrup, M., 17 Oct 2006, In: Synthesis. 20, p. 3478-3484 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Synthesis of substituted 2-cyanoarylboronic esters

    Lysén, M., Hansen, H. M., Begtrup, M. & Kristensen, Jesper Langgaard, 17 Mar 2006, In: Journal of Organic Chemistry. 71, 6, p. 2518-20 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor

    L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In: Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists

    Marcher, Emil, Halberstadt, A. L., Klein, A. K., Chatha, M., Jademyr, S., Jensen, Anders A. & Kristensen, Jesper Langgaard, 2020, In: ACS Chemical Neuroscience. 11, p. 1238-1244

    Research output: Contribution to journal › Letter › Research › peer-review

  17. Published

    Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist

    Marcher, Emil, Nykodemová, J., Harpsøe, Kasper, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2023, In: ACS Medicinal Chemistry Letters. 14, 3, p. 319–325

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    An improved, scalable synthesis of the selective serotonin 2A receptor agonist 25CN-NBOH

    Marcher, Emil, Nykodemova, J. & Kristensen, Jesper Langgaard, 2021, In: SynOpen. 5, 2, p. 158-160

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension

    Mertz, Nina, Larsen, Susan Weng, Kristensen, Jesper Langgaard, Østergaard, Jesper & Larsen, C., 27 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3079–3087 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    25CN-NBOH: A selective agonist for in vitro and in vivo investigations of the serotonin 2A receptor

    Marcher, Emil, Jensen, Anders A. & Kristensen, Jesper Langgaard, 2021, In: ChemMedChem. 16, 21, p. 3263-3270

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Novel 4-(piperidin-4-yl)-1-hydroxypyrazoles as gamma-aminobutyric acidA receptor ligands: synthesis, pharmacology, and structure-activity relationships

    Møller, H. A., Sander, T., Kristensen, Jesper Langgaard, Nielsen, Birgitte, Krall, J., Bergmann, M. L., Christiansen, B., Balle, T., Jensen, Anders A. & Frølund, Bente, 2010, In: Journal of Medicinal Chemistry. 53, 8, p. 3417-3421

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH

    Nielsen, L. M., Holm, N. B., Leth-Petersen, S., Kristensen, Jesper Langgaard, Olsen, L. & Linnet, Kristian, 2017, In: Drug Testing and Analysis. 9, 5, p. 671–679

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Synthesis and characterisation of substrate-based peptides as inhibitors of histone demethylase KDM4C

    Nielsen, S. D., Leurs, U., Bergner, M., Barris, S. A., Devkota, K., Meyer, K., Iaria, D., McCaughan, J., Lohse, B., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 13 Jun 2016, In: Protein and Peptide Letters. 23, 9, p. 772 - 776 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Synthesis of N-alkylated amino acids using fluorous-tagged hydroxylamines

    Nielsen, S. D., Smith, G. P., Begtrup, M. & Kristensen, Jesper Langgaard, 22 Jul 2011, In: Tetrahedron. 67, 29, p. 5261-5267

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Synthesis and application of a new fluorous-tagged ammonia equivalent

    Nielsen, S. D., Smith, G., Begtrup, M. & Kristensen, Jesper Langgaard, 2010, In: Chemistry: A European Journal. 16, 15, p. 4557-4566

    Research output: Contribution to journal › Journal article › Research › peer-review

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