Ole Jannik Bjerrum

Ole Jannik Bjerrum

Professor, emeritus


  1. 1979
  2. Published

    Immunochemically identical hydrophilic and amphiphilic forms of the bovine adrenomedullary dopamine beta-hydroxylase

    Bjerrum, Ole Jannik, Helle, K. B. & Bock, E. M., 1979, In: Biochemical Journal. 181, 1, p. 231-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1987
  4. Published

    Modification of beta-2-microglobulin in sera from patients with small cell lung cancer: evidence for involvement of a serine protease.

    Nissen, Mogens Holst, Bjerrum, Ole Jannik, Plesner, T., Wilken, M. & Rørth, M., 1987, In: Clinical and Experimental Immunology. 67, 2, p. 425-32 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1995
  6. Published

    Electrophoretic and chromatographic differentiation of two forms of albumin in equilibrium at neutral pH. New screening technique of ligand binding to albumin

    Bjerrum, Ole Jannik, 1995, In: Electrophoresis. 16, 8, p. 1401-1407 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Growth hormone releasing hexapeptide (GHRP-6)-activates the inositol (1,4,5)-Triphosphate/diacylglycerol pathway

    Bjerrum, Ole Jannik, 1995, In: Journal of Receptors and Signal Transduction. 15, 1-4, p. 311-323 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 1997
  9. Published

    A simple method for the preparation and purification of C1 complement cleaved beta 2-microglobulin from human serum.

    Nissen, Mogens Holst, Johansen, B. & Bjerrum, Ole Jannik, 1997, In: Journal of Immunological Methods. 205, 1, p. 29-33 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Relative contribution of advanced glycation and nitric oxide synthase inhibition to amino guanidine- mediated renoprotection in diabetic rats

    Bjerrum, Ole Jannik, 1997, In: Diabetologia. 40, 10, p. 1141-1151 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 1999
  12. Published

    A novel inhibitor of advanced glycation end- product formation inhibits mesenteric vascular hypertrophy in experimental diabetes

    Bjerrum, Ole Jannik, 1999, In: Diabetologica. 42, p. 472-479 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural heterogeneity of the binding sites of HSA for phenyl-groups and medium chain fatty acids. Demonstration of equilibrium between different binding conformations

    Bjerrum, Ole Jannik & Bjerrum, Morten Jannik, 1999, In: European Journal of Biochemistry. 260, p. 470-476 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2005
  15. Published

    Centrally mediated anti-noceptive action of GABAA receptor agonists in the spared nerve injury model of neuropathic pain

    Bjerrum, Ole Jannik, 2005, In: European Journal of Pharmaceutical Sciences. 516, p. 131-138 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    How first time-in human studies are being performed; A survey of phase 1 dose escalation trials in healthy volunteers published between 1995-2004

    Bjerrum, Ole Jannik, 2005, In: Journal of Clinical Pharmacology. 45, p. 1123-1136 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2006
  18. Published

    Venlafaxine compromises the antinoceptive actions of gabapentin in rat models of neuropathic and persistent pain

    Bjerrum, Ole Jannik, 2006, In: Psychopharmacology. 187, p. 364-375 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2007
  20. Published

    Effective integration of systems biology, biomarkers, biosimulation and modelling in streamlining drug development

    Krishna, R., Schaefer, H. G. & Bjerrum, Ole Jannik, 2007, In: European Journal of Pharmaceutical Sciences. 31, 1, p. 62-67

    Research output: Contribution to journalLetterResearch

  21. Published

    The antinociceptive efficacy of buprenorphine administered through the drinking water of rats

    Jessen, L., Bjerrum, Ole Jannik & Christensen, S., 2007, In: Laboratory Animals. Journal of the Laboratory Animal Science Association. 41, 2, p. 185-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The importance of genetic background on pain behaviours and pharmacological sensitivity in the rat spared serve injury model of peripheral neuropathic pain

    Rode, F., Thomsen, M., Jensen, D. G., Blackburn-Munro, G., Bjerrum, Ole Jannik & Broløs, T., 2007, In: European Journal of Pharmacology. 564, 1-3, p. 103-111

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2008
  24. Published

    Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain

    Hald, A., Ding, M., Egerod, Kristoffer Lihme, Hansen, R. R., Konradsen, D., Jørgensen, S. G., Atalay, B., Nasser, A., Bjerrum, Ole Jannik & Heegaard, Anne-Marie, 2008, In: Pharmacology, Biochemistry and Behavior. 91, 1, p. 38-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The EUFEPS workshop on institutional peer review "The ultimate tool to advance the pharmaceutical sciences?" A continuing story: A continuing story

    Crommelin, D. J. A. & Bjerrum, Ole Jannik, 2008, In: European Journal of Pharmaceutical Sciences. 35, 4, p. 361-364

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Western blotting: immunoblotting

    Bjerrum, Ole Jannik & Heegaard, N. H., 2008, Encyclopedia of Life Sciences. Wiley

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  27. 2009
  28. Published

    Co-administered gabapentin and venlafaxine in nerve injured rats: effect on mechanical hypersensitivity, motor function and pharmacokinetics

    Folkesson, A. J. M., Honoré, P. G. H. & Bjerrum, Ole Jannik, 2009, In: Scandinavian Journal of Pain. 1, 2, p. 91-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2010
  30. Published

    Fast detection of adverse drug reactions of new drugs by community pharmacists

    Christensen, S. T. & Bjerrum, Ole Jannik, 2010, In: Drug Safety. 33, 10, p. 928

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  31. Published

    Genetik kan forudsige følsomhed for smerte

    Nasser, A., Bjerrum, Ole Jannik, Heegaard, Anne-Marie & Møller, L. B., 2010, In: Lægemiddelforskning. 2010, p. 34-36

    Research output: Contribution to journalJournal articleResearch

  32. Published

    Low dose of donepezil improves gabapentin analgesia in the rat spared nerve injury model of neuropathic pain: single and multiple dosing studies

    Folkesson, A., Honoré, P. H., Andersen, L. M., Kristensen, P. J. & Bjerrum, Ole Jannik, 2010, In: Journal of Neural Transmission. 117, p. 1377-1385

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Pharmacokinetics of fexofenadine: evaluation of a microdose and assessment of absolute oral bioavailability

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, B., Oosterhuis, B., Bjerrum, Ole Jannik, Rowland, M. & Garner, C., 2010, In: European Journal of Pharmaceutical Sciences. 40, 2, p. 125-31 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2011
  35. Published

    Beta-lactam antibiotic as dose dependent analgesic treatment of neuropathic pain

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  36. Published

    Ceftriaxone, an EAAT-2 transporter inducer, shows antinociceptive effects in acute and neuropathic pain models

    Bjerrum, Ole Jannik, Abrahamsen, B. & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  37. Published

    Characterization of drug combination effects in a rat model of neuropathic pain ny population modelling and simulation of response-time profiles

    Bjerrum, Ole Jannik & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  38. Published

    Combination therapy for neuropathic pain: Donepezil improves gabapentins antinoceptive effect in SNI rats

    Bjerrum, Ole Jannik & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  39. Published

    Decrease in nocifensive behaviour in rats after treatment with the EAAT-2 transporter inducer cetriaxone

    Bjerrum, Ole Jannik, Honoré, P. G. H. & Abrahamsen, B., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  40. Published

    Development of quantitative Pharmacology Pharmacometrics in Denmark

    Bjerrum, Ole Jannik & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  41. Published

    Development of quantitative pharmacology-pharmacometrics in Denmark

    Honoré, P. G. H., Bjerrum, Ole Jannik, Lund, Trine Meldgaard, Angelo, H., Ingwersen, S. H., Thygesen, P., Kristensen, K. & Larsen, F., 2011.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Effects of the excitatory amino acid transporter subtype 2(EAAT-2) inducer ceftriaxone on different pain modalities in rat

    Eljaja, L., Bjerrum, Ole Jannik, Honoré, P. G. H. & Abrahamsen, B., 2011, In: Scandinavian Journal of Pain. 2, 3, p. 132-136 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Excellence in education and training advances competitiveness of the pharmaceutical industry in Europe

    Bjerrum, Ole Jannik, 2011, In: European Journal of Pharmaceutical Sciences. 44, 2, p. 174-175 2 p.

    Research output: Contribution to journalComment/debateResearch

  44. Published

    Neuropathic pain models in the development of analgesic drugs

    Honoré, P. G. H., Basnet, A., Eljaja, L., Kristensen, P., Neustrup, L. M., Møllgaard, P. & Bjerrum, Ole Jannik, 2011, In: Scandinavian Journal of Pain. 2, 4, p. 172-177 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    Pharmacy student driven detection of adverse drug reactions in the community pharmacy setting

    Christensen, S. T., Søndergaard, B., Honoré, P. H. & Bjerrum, Ole Jannik, 2011, In: Pharmacoepidemiology and Drug Safety. 20, p. 399-404 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Population modelling and simulation of response - time profiles for charaterization of drug combination effect in a rat model of neuropathic pain

    Bjerrum, Ole Jannik, Basnet, A. & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  47. Published

    Population pharmacodynamic modeling and simulation as a method to characterize drug combination effects i a rat model of neuropathic pain

    Bjerrum, Ole Jannik & Honoré, P. G. H., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  48. Published

    Predictive validity of pharmacologic interventions in animal models of neuropathic pain

    Honoré, P. G. H., Basnet, A., Kristensen, P., Andersen, L. M., Neustrup, S., Møllgaard, P., Eljaja, L. & Bjerrum, Ole Jannik, 2011, In: Scandinavian Journal of Pain. 2, 4, p. 178-184 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Systems pharmacology from an Academic Perspective

    Bjerrum, Ole Jannik & Boonen, H. C. M., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  50. Published

    The hph-1 mouse mutant deficient in tetrahydrobiopterin show reduced acute and chronic inflammatory pain

    Bjerrum, Ole Jannik, Nasser, A. & Heegaard, Anne-Marie, 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  51. Published

    The hph-1 mouse with inherited deficiency in GTP cyclohydrolase 1 shows reduced inflammatory pain behavior

    Bjerrum, Ole Jannik & Nasser, A., 2011.

    Research output: Contribution to conferencePosterResearchpeer-review

  52. Published

    Comparative pharmacokinetics between a microdose and therapeutic dose for clarithromycin, sumatriptan, propafenone, paracetamol (acetaminophen) and phenobarbital in human volunteers

    Lappin, G., Shishikura, Y., Jochemsen, R., Weaver, R. J., Gesson, C., Houston, J. B., Oosterhuis, B., Bjerrum, Ole Jannik, Grynkiewicz, G., Alder, J., Rowland, M. & Garner, C., 20 Apr 2011, In: European Journal of Pharmaceutical Sciences. 43, 3, p. 141-150 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The spared nerve injury (SNI) model of induced mechanical allodynia in mice

    Richner, M., Bjerrum, Ole Jannik, Nykjær, A. & Vaegter, C. B., 18 Aug 2011, In: Journal of Visualized Experiments. 54, p. e3092

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2012
  55. Published

    Sortilins in neuropathic pain

    Richner, M., Bjerrum, Ole Jannik, Koninck, Y. D., Nykjaer, A. & Vaegter, C. B., 29 Dec 2012, In: Scandinavian Journal of Pain. 3, 3, p. 183-184 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  56. 2013
  57. Published

    Donepezil anvendt ved neuropatisk smerte

    Bjerrum, Ole Jannik & Bjerrum, H. J., 2013, In: Ugesskrift for læger. 175, 42, p. 2493-2494 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Donepezil as add-on to gabapentin for post-traumatic neuropathic pain: an exploratory study

    Basnet, A., Butler, S., Honoré, P. G. H., Butler, M., Gordh, T. E., Kristensen, K. K. & Bjerrum, Ole Jannik, 2013, In: Acta Anaesthesiologica Scandinavica. 58, 1, p. 61-73 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Dose and administration-period play a key role in the effect of ceftriaxone on neuropathic pain in CCi-operated rats

    Bjerrum, Ole Jannik, Honoré, P. G. H., Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Gegelashvili, G., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  60. Published

    Dose-dependent effect of ceftriaxone (A beta-lactam) on mechanical pain hypersensitivity in the CCI nerve rat model

    Bjerrum, Ole Jannik, Frederiksen, K. K., Kristensen, P., Abrahamsen, B. & Honoré, P. G. H., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  61. Published

    Fixed Dose Combinations. The Physician attitude to the wider use. A pilot study

    Bjerrum, Ole Jannik & Vana, V., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  62. Published

    Fixed drug combinations: are current regulatory guidelines in the EU and US adequate for effectively guiding Development?

    Bjerrum, Ole Jannik, Gautam, Y. & Schmiegelow, M., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  63. Published

    Orphan disease council - A new interdiciplinary private/public partnership promoting the Development of orphan medicinal products

    Bjerrum, Ole Jannik, Hove, H. B., Dali, C., Callesen, L., Ludvig, G. & Thyregod, L., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

  64. Published

    Pain perception and Dopa Responsive Dystonia

    Bjerrum, Ole Jannik, Nasser, A., Møller, A. T., Møller, B. & Jensen, T. S., 2013.

    Research output: Contribution to conferencePosterResearchpeer-review

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