Osman Asghar Mirza

Osman Asghar Mirza

Associate Professor


  1. 1999
  2. Published

    Crystallization and preliminary X-ray analysis of birch-pollen allergen Bet v 1 in complex with a murine monoclonal IgG Fab' fragment

    Spangfort, M. D., Mirza, Osman Asghar & Gajhede, Michael, Dec 1999, In: Acta Crystallographica. Section D: Biological Crystallography. 55, Pt 12, p. 2035-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2000
  4. Published

    Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification.

    Ostergaard, L., Teilum, Kaare, Mirza, Osman Asghar, Mattsson, O., Petersen, M., Welinder, K. G., Mundy, J., Gajhede, Michael & Henriksen, A., 2000, In: Plant Molecular Biology. 44, 2, p. 231-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Crystallization and preliminary X-ray studies of recombinant amylosucrase from Neisseria polysaccharea

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., Potocki de Montalk, G., Remaud-Simeon, M., Sarcabal, P., Willemot, R. M., Monsan, P. & Gajhede, M., Feb 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 2, p. 203-5 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase

    Mirza, Osman Asghar, Henriksen, A., Ostergaard, L., Welinder, K. G. & Gajhede, Michael, Mar 2000, In: Acta Crystallographica. Section D: Biological Crystallography. 56, Pt 3, p. 372-5 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1

    Mirza, Osman Asghar, Henriksen, A., Ipsen, H., Larsen, J. N., Wissenbach, M., Spangfort, M. D. & Gajhede, Michael, 1 Jul 2000, In: Journal of Immunology. 165, 1, p. 331-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2001
  9. Major venom allergen of yellow jackets, Ves v 5: structural characterization of a pathogenesis-related protein superfamily

    Henriksen, A., King, T. P., Mirza, Osman Asghar, Monsalve, R. I., Meno, K., Ipsen, H., Larsen, J. N., Gajhede, M. & Spangfort, M. D., 2001, In: Proteins: Structure, Function, and Bioinformatics. 45, 4, p. 438-48 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions

    Henriksen, A., Mirza, Osman Asghar, Indiani, C., Teilum, Kaare, Smulevich, G., Welinder, K. G. & Gajhede, Michael, 2001, In: Protein Science. 10, 1, p. 108-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Amylosucrase, a glucan-synthesizing enzyme from the alpha-amylase family

    Skov, L. K., Mirza, Osman Asghar, Henriksen, A., De Montalk, G. P., Remaud-Simeon, M., Sarçabal, P., Willemot, R. M., Monsan, P. & Gajhede, Michael, 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 25273-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Crystal structures of amylosucrase from Neisseria polysaccharea in complex with D-glucose and the active site mutant Glu328Gln in complex with the natural substrate sucrose

    Mirza, Osman Asghar, Skov, L. K., Remaud-Simeon, M., Potocki de Montalk, G., Albenne, C., Monsan, P. & Gajhede, M., 31 Jul 2001, In: Biochemistry. 40, 30, p. 9032-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2002
  14. Published

    Maltooligosaccharide disproportionation reaction: an intrinsic property of amylosucrase from Neisseria polysaccharea

    Albenne, C., Skov, L. K., Mirza, Osman Asghar, Gajhede, Michael, Potocki-Véronèse, G., Monsan, P. & Remaud-Simeon, M., 11 Sep 2002, In: F E B S Letters. 527, 1-3, p. 67-70 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Site-directed mutagenesis of key amino acids in the active site of amylosucrase from Neisseria polysaccharea

    Albenne, C., Potocki De Montalk, G., Monsan, P., Skov, L., Mirza, Osman Asghar, Gajhede, Michael & Remaud-Simeon, M., 1 Dec 2002, In: Biologia - Section Cellular and Molecular Biology. 57, SUPPL. 11, p. 119-128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Oligosaccharide and sucrose complexes of amylosucrase. Structural implications for the polymerase activity

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., Dar, I., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 6 Dec 2002, In: Journal of Biological Chemistry. 277, 49, p. 47741-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2003
  18. Published

    Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis

    Spangfort, M. D., Mirza, Osman Asghar, Ipsen, H., Van Neerven, R. J. J., Gajhede, Michael & Larsen, J., 2003, In: Journal of Immunology. 171, 6, p. 3084-90 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Rational and combinatorial engineering of the glucan synthesizing enzyme amylosucrase

    Albenne, C., Van Der Veen, B. A., Potocki-Véronèse, G., Joucla, G., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Monsan, P. & Remaud-Simeon, M., 1 Aug 2003, In: Biocatalysis and Biotransformation. 21, 4-5, p. 271-277 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2004
  21. Published

    Molecular basis of the amylose-like polymer formation catalyzed by Neisseria polysaccharea amylosucrase

    Albenne, C., Skov, L., Mirza, Osman Asghar, Gajhede, Michael, Feller, G., D'Amico, S., André, G., Potocki-Véronèse, G., van der Veen, B. A., Monsan, P. & Remaud-Simeon, M., 2 Jan 2004, In: Journal of Biological Chemistry. 279, 1, p. 726-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Crystal structure of sucrose phosphorylase from Bifidobacterium adolescentis

    Sprogøe, D., van den Broek, L. A. M., Mirza, Osman Asghar, Kastrup, Jette Sandholm Jensen, Voragen, A. G. J., Gajhede, Michael & Skov, L., 10 Feb 2004, In: Biochemistry. 43, 5, p. 1156-62 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Crystal structure of the covalent intermediate of amylosucrase from Neisseria polysaccharea

    Jensen, M. H., Mirza, Osman Asghar, Albenne, C., Remaud-Simeon, M., Monsan, P., Gajhede, Michael & Skov, L., 23 Mar 2004, In: Biochemistry. 43, 11, p. 3104-10 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2006
  25. Published

    Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion

    Mirza, Osman Asghar, Henriksen, L. S., Sprogøe, D., van den Broek, L. A. M., Beldman, G., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2006, In: Journal of Biological Chemistry. 281, 46, p. 35576-84 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209

    Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose

    Skov, L. K., Mirza, Osman Asghar, Sprogøe, D., van der Veen, B., Remaud-Simeon, M., Albenne, C., Monsan, P. & Gajhede, Michael, 1 Jan 2006, In: Biocatalysis and Biotransformation. 24, 1-2, p. 99-105 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY

    Mirza, Osman Asghar, Guan, L., Verner, G., Iwata, S. & Kaback, H. R., 22 Mar 2006, In: E M B O Journal. 25, 6, p. 1177-83 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Fumarate reductase and succinate oxidase activity of Escherichia coli complex II homologs are perturbed differently by mutation of the flavin binding domain

    Maklashina, E., Iverson, T. M., Sher, Y., Kotlyar, V., Andréll, J., Mirza, Osman Asghar, Hudson, J. M., Armstrong, F. A., Rothery, R. A., Weiner, J. H. & Cecchini, G., 21 Apr 2006, In: Journal of Biological Chemistry. 281, 16, p. 11357-65 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. The ABC transporter protein OppA provides protection against experimental Yersinia pestis infection

    Tanabe, M., Atkins, H. S., Harland, D. N., Elvin, S. J., Stagg, A. J., Mirza, Osman Asghar, Titball, R. W., Byrne, B. & Brown, K. A., Jun 2006, In: Infection and Immunity. 74, 6, p. 3687-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2007
  32. Published

    Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells

    Yu, J., Lubinsky, D., Tsomaia, N., Huang, Z., Taylor, L., Mierke, D., Navarro, J., Mirza, Osman Asghar & Polgar, P., 2007, In: Journal of Cellular Biochemistry. 101, 1, p. 192-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Structural determination of wild-type lactose permease

    Guan, L., Mirza, Osman Asghar, Verner, G., Iwata, S. & Kaback, H. R., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 39, p. 15294-15298

    Research output: Contribution to journalJournal articleResearchpeer-review

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