Osman Asghar Mirza
Associate Professor
Biopharmaceuticals
Jagtvej 162, 2100 København Ø
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Strukturer af membranproteiner: nøglen til rationelt lægemiddeldesign
Hald, H. & Mirza, Osman Asghar, Dec 2010, In: Lægemiddelforskning. 2010, p. 13-15Research output: Contribution to journal › Journal article › Communication
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Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency
Beich-Frandsen, M., Pickering, Darryl S, Mirza, Osman Asghar, Johansen, Tommy Nørskov, Greenwood, J., Vestergaard, Bente, Schousboe, Arne, Gajhede, Michael, Liljefors, T. & Kastrup, Jette Sandholm Jensen, 2008, In: Journal of Medicinal Chemistry. 51, 5, p. 1459-63Research output: Contribution to journal › Journal article › Research › peer-review
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Structures of OppA and PstS from Yersinia pestis indicate variability of interactions with transmembrane domains
Tanabe, M., Mirza, Osman Asghar, Bertrand, T., Atkins, H. S., Titball, R. W., Iwata, S., Brown, K. A. & Byrne, B., 2007, In: Acta Crystallographica. Section D: Biological Crystallography. 63, 11, p. 1185-1193Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer
Pippione, A. C., Kovachka, S., Vigato, C., Bertarini, L., Mannella, I., Sainas, S., Rolando, B., Denasio, E., Piercy-Mycock, H., Romalho, L., Salladini, E., Adinolfi, S., Zonari, D., Peraldo-Neia, C., Chiorino, G., Passoni, A., Mirza, O. A., Frydenvang, K., Pors, K., Lolli, M. L. & 3 others, , 2024, In: European Journal of Medicinal Chemistry. 268, 20 p., 116193.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism
Kobberø, S. D., Gajhede, Michael, Mirza, Osman Asghar, Kløverpris, S., Kjær, T. R., Mikkelsen, J. H., Boesen, T. & Oxvig, C., 2022, In: Nature Communications. 13, 1, 16 p., 6084.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions
Henriksen, A., Mirza, Osman Asghar, Indiani, C., Teilum, Kaare, Smulevich, G., Welinder, K. G. & Gajhede, Michael, 2001, In: Protein Science. 10, 1, p. 108-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter
Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, Osman Asghar, Krusong, K., Carpenter, E. P., Rutherford, N. G., Hadden, J. M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S. G., Hope, R. J., Norbertczak, H. T., Roach, P. C. J., Iwata, S., Henderson, P. J. F. & Cameron, A. D., 2008, In: Science. 322, 5902, p. 709-713Research output: Contribution to journal › Journal article › Research › peer-review
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Structural rearrangements of sucrose phosphorylase from Bifidobacterium adolescentis during sucrose conversion
Mirza, Osman Asghar, Henriksen, L. S., Sprogøe, D., van den Broek, L. A. M., Beldman, G., Kastrup, Jette Sandholm Jensen & Gajhede, Michael, 2006, In: Journal of Biological Chemistry. 281, 46, p. 35576-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY
Mirza, Osman Asghar, Guan, L., Verner, G., Iwata, S. & Kaback, H. R., 22 Mar 2006, In: E M B O Journal. 25, 6, p. 1177-83 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural determination of wild-type lactose permease
Guan, L., Mirza, Osman Asghar, Verner, G., Iwata, S. & Kaback, H. R., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 39, p. 15294-15298Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302772
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Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol
Research output: Contribution to journal › Journal article › Research › peer-review
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275
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Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]
Research output: Contribution to journal › Journal article › Research › peer-review
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243
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Activity of the Human Rhinovirus 3C Protease Studied in Various Buffers, Additives and Detergents Solutions for Recombinant Protein Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published