Paul Robert Hansen

Paul Robert Hansen

Associate Professor

Member of:

    ORCID: 0000-0001-9357-8001

    Publication year:
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    1 - 50 out of 180Page size: 50
    1. 2024
    2. Published

      Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

      Primo, L. M. D. G., Roque-Borda, C. A., Carnero Canales, C. S., Caruso, I. P., de Lourenço, I. O., Colturato, V. M. M., Sábio, R. M., de Melo, F. A., Vicente, E. F., Chorilli, M., da Silva Barud, H., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2024, In: Carbohydrate Polymers. 323, 17 p., 121449.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Accepted/In press

      Fmoc Solid-Phase Peptide Synthesis: (Update of 2015 Chapter)

      Hansen, Paul Robert & Oddo, A., 2024, (Accepted/In press) Methods in Molecular Biology Peptide Antibodies . Vol. 2.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    4. Published

      Nanogel delivery systems for cationic peptides: More than a ‘One Size Fits All’ solution

      Kłodzińska, S. N., Wang, Qiuyue, Molchanova, N., Mahmoudi, N., Vallooran, J. J., Hansen, Paul Robert, Jenssen, H. & Nielsen, Hanne Mørck, 2024, In: Journal of Colloid and Interface Science. 663, p. 449-457

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Reflections on a Copenhagen–Minneapolis Axis in Bioorganic Chemistry

      Barany, G. & Hansen, Paul Robert, 2024, In: Molecules (Basel, Switzerland). 29, 6, 62 p., 1317.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2023
    7. Published

      N-acetylcysteine-chitosan nanoparticles with the Ctx(Ile21)-Ha peptide grafted onto the surface can rescue the susceptibility of pre-extensively resistant Mycobacterium tuberculosis

      Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2 Oct 2023. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    8. Published

      Rifampicin-loaded N-acetylcysteine-chitosan nanoparticles surface-grafted with a peptide exhibit potent activity against multidrug-resistant Mycobacterium tuberculosis

      Roque-Borda, C. A., Primo, L. M. D. G., Vicente, E. F., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 11 Jun 2023. 1 p.

      Research output: Contribution to conference › Poster › Research › peer-review

    9. Published

      Antibodies to calnexin and mutated calreticulin are common in human sera

      Kyllesbech, C., Trier, N. H., Mughal, F. P., Hansen, Paul Robert, Holmström, M. O., Fassi, Daniel El , Hasselbalch, H., Skov, V., Kjær, L., Andersen, Mads Hald, Ciplys, E., Slibinskas, R., Fredriksen, Jette Lautrup, Højrup, P. & Houen, G., 2023, In: Current Research in Translational Medicine. 71, 2, 103380.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

      Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

      Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Accepted/In press

      The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

      Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      The effect of Cys15 and Cys21 replacement with Ala, Ser and Lys on the anti Mycobacterium tuberculosis activity of antimicrobial peptide B1CTcu5

      Roque-Borda, C. A., Costa de Pontes, J. T., Domingos da Silva, L. H., Caroline dos Santos, I. C. D. S., Aparecida Resende, F., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2023.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    14. 2022
    15. Published

      C-locked analogs of the antimicrobial peptide BP214

      Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

      Lone, A. B. N., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 2022, In: European Journal of Medicinal Chemistry Reports. 6, 7 p., 100080.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C

      Trier, N. H., Valdarnini, N., Fanelli, I., Rovero, P., Hansen, Paul Robert, Schafer, C., Ciplys, E., Slibinskas, R., Pociot, F., Friis, T. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 16 p., 4424.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Production and characterization of peptide antibodies to the C-terminal of frameshifted calreticulin associated with myeloproliferative diseases

      Mughal , F. P., Bergmann , A. C., Huynh , H. U. B., Jørgensen, S. H., Mansha , I., Kesmeh , M., Schürch, P. M., Theocharides, A. P. A., Hansen, Paul Robert, Friis , T., Holmeren , M. Ö., Ciplys , E., Slibinskas , R., Højrup, P., Houen, G. & Trier, N. H., 2022, In: International Journal of Molecular Sciences. 23, 12, 21 p., 6803.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Reactivity of Rheumatoid Arthritis-Associated Citrulline-Dependent Antibodies to Epstein-Barr Virus Nuclear Antigen1-3

      Fanelli, I., Rovero, P., Hansen, Paul Robert, Frederiksen, J. L., Houen, G. & Trier, N. H., 2022, In: Antibodies. 11, 1, 15 p., 20.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. 2021
    21. Published

      Specific Reactivity of Anti-Citrullinated Protein Antibodies to Citrullinated Peptides Associated with Rheumatoid Arthritis

      Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 1 Jan 2021, Advances in Clinical Immunology, Medical Microbiology, COVID-19, and Big Data. R. B. (ed.). Jenny Stanford Publishing Pte. Ltd, p. 41-54 14 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    22. Published

      Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum

      Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

      Wester, A., Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Specificity of anti-citrullinated protein antibodies to citrullinated α-enolase peptides as a function of epitope structure and composition

      Fanelli, I., Rovero, P., Hansen, Paul Robert, Fredriksen, Jette Lautrup, Houen, G. & Trier, N. H., 2021, In: Antibodies. 10, 3, 12 p., 27.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2020
    26. Published

      Specificity of Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis

      Trier, N. H., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 30 Jun 2020, Jenny Stanford Publishing Pte. Ltd. ( Current Issues in Medicine: Surgical and Medical Specialities).

      Research output: Book/Report › Book › Research › peer-review

    27. Published

      Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography

      Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Analogues of a Cyclic Antimicrobial Peptide with a Flexible Linker Show Promising Activity Against Pseudomonas aeruginosa and Staphylococcus aureus

      Thomsen, T. T., Mendel, H. C., Al-Mansour, W., Oddo, A., Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: Antibiotics. 9, 7, 13 p., 366.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides

      Greco, I., Molchanova, N., Holmedal, E., Jenssen, H., Hummel, B. D., Watts, J. L., Håkansson, J., Hansen, Paul Robert & Svenson, J., 2020, In: Scientific Reports. 10, 13 p., 13206.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency

      Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A., Berg, Jais Oliver, Thulstrup, Peter Waaben, Franzyk, Henrik, Edvinsson, L., Sams, A., Sheykhzade, Majid & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences (Online). 21, 4, p. 1-15 15 p., 1343.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Halogenation as a tool to tune antimicrobial activity of peptoids

      Molchanova, N., Nielsen, J. E., Sørensen, K. B., Prabhala, B. K., Hansen, Paul Robert, Lund, R., Barron, A. E. & Jenssen, H., 2020, In: Scientific Reports. 10, 10 p., 14805.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position

      Jensen, S. K., Thomsen, T. T., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences . 21, 16, 18 p., 5829.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Synthesis of Peptoids Containing MultipleNhtrp andNtrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection

      Lone, A., Arnous, A., Hansen, Paul Robert, Mojsoska, B. & Jenssen, H., 2020, In: Frontiers in Chemistry. 8, 12 p., 370.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. 2019
    36. Published

      Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

      Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Peptides, antibodies, peptide antibodies and more

      Trier, N., Hansen, Paul Robert & Houen, G., 11 Nov 2019, In: International Journal of Molecular Sciences (Online). 20, 22 p., 6289.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Published

      A Biophysical Study of the Interactions between the Antimicrobial Peptide Indolicidin and Lipid Model Systems

      Nielsen, J. E., Lind, T. K., Lone, A., Gerelli, Y., Hansen, Paul Robert, Jenssen, H., Cárdenas, M. & Lund, R., 2019, In: B B A - Biomembranes. 1861, 7, p. 1355-1364

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

      Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections

      Greco, I., Emborg, A., Jana, B., Molchanova, N., Oddo, A., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Scientific Reports. 9, 12 p., 3679.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Fine mapping of glutamate decarboxylase 65 epitopes reveals dependency of hydrophobic amino acids for specific interactions

      Valdarnini, N., Holm, B., Hansen, Paul Robert, Rovero, P., Houen, G. & Trier, N. H., 2019, In: International Journal of Molecular Sciences (Online). 20, 13 p., 2909.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

      Trier, N., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 2019, In: Antibodies. 8, 2, 10 p., 37.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Structure-Activity Study of an All-D Antimicrobial Octapeptide D2D

      Lone, A., Thomsen, T. T., Nielsen, J. E., Thulstrup, Peter Waaben, Klitgaard, R. N., Løbner-Olesen, Anders, Lund, R., Jenssen, H. & Hansen, Paul Robert, 2019, In: Molecules. 24, 24, 17 p., 4571.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

      Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, Peter Waaben, Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Molecules. 24, 6, 16 p., 1121.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. 2018
    46. Published

      Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

      Kłodzińska, S. N., Molchanova, N., Franzyk, Henrik, Hansen, Paul Robert, Damborg, Peter Panduro & Nielsen, Hanne Mørck, Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

      Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, Hanne Mørck, Damborg, Peter Panduro & Hansen, Paul Robert, 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Fmoc Solid-Phase Synthesis of Human a-Calcitonin Gene- Related Peptide and Two Carboxyfluorescein-labeled Analogs

      Ahmed, L. S., Abdolalizadeh, B., Sheykhzade, Majid & Hansen, Paul Robert, 11 Feb 2018.

      Research output: Contribution to conference › Poster › Research › peer-review

    49. Published

      Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

      Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2018, In: Journal of Peptide Science. 24, 7, 8 p., e3098.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

      Karathanasi, G., Bojer, Martin Saxtorph, Baldry, M., Johannessen, B. A., Wolff, S., Greco, I., Kilstrup, M., Hansen, Paul Robert & Ingmer, Hanne, 2018, In: Scientific Reports. 8, 1, 11 p., 3562.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Review on abyssomicins: Inhibitors of the chorismate pathway and folate biosynthesis

      Sadaka, C., Ellsworth, E., Hansen, Paul Robert, Ewin, R., Damborg, Peter Panduro & Watts, J. L., 2018, In: Molecules. 23, 6, 25 p., 1371.

      Research output: Contribution to journal › Review › Research › peer-review

    52. Published

      The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

      Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, Paul Robert, Brasen, C., Gajhede, Michael, Rahman, M. & Mirza, Osman Asghar, 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. 2017
    54. Published

      Advances in development of antimicrobial peptidomimetics as potential drugs

      Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 28 Aug 2017, In: Molecules. 22, 9, 60 p., 1430.

      Research output: Contribution to journal › Review › Research › peer-review

    55. Published

      Broadening CD4(+) and CD8(+) T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

      Filskov, J., Mikkelsen, M., Hansen, Paul Robert, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Andersen, P., Bukh, Jens & Agger, E., Jul 2017, In: Journal of Virology. 91, 14, 18 p., e00130-17.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

      Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Methods in Molecular Biology: Antimicrobial Peptides Methods and Protocols

      Hansen, Paul Robert (ed.), 1 Jan 2017, Springer. 439 p.

      Research output: Book/Report › Book › Research › peer-review

    58. Published

      Chemical Synthesis of Antimicrobial Peptides.

      Münzker, L., Oddo, A. & Hansen, Paul Robert, 2017, Chemical Synthesis of Antimicrobial Peptides: Münzker L, Oddo A, Hansen PR. Methods Mol Biol. 2017; . Hansen, P. R. (ed.). Springer, Vol. 1548. p. 35-49.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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