Paul Robert Hansen

Paul Robert Hansen

Associate Professor


  1. 2024
  2. Published

    Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

    Primo, L. M. D. G., Roque-Borda, C. A., Carnero Canales, C. S., Caruso, I. P., de Lourenço, I. O., Colturato, V. M. M., Sábio, R. M., de Melo, F. A., Vicente, E. F., Chorilli, M., da Silva Barud, H., Barbugli, P. A., Franzyk, Henrik, Hansen, Paul Robert & Pavan, F. R., 2024, In: Carbohydrate Polymers. 323, 17 p., 121449.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Nanogel delivery systems for cationic peptides: More than a ‘One Size Fits All’ solution

    Kłodzińska, S. N., Wang, Qiuyue, Molchanova, N., Mahmoudi, N., Vallooran, J. J., Hansen, Paul Robert, Jenssen, H. & Nielsen, Hanne Mørck, 2024, In: Journal of Colloid and Interface Science. 663, p. 449-457

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Reflections on a Copenhagen–Minneapolis Axis in Bioorganic Chemistry

    Barany, G. & Hansen, Paul Robert, 2024, In: Molecules (Basel, Switzerland). 29, 6, 62 p., 1317.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2023
  6. Published

    Antibodies to calnexin and mutated calreticulin are common in human sera

    Kyllesbech, C., Trier, N. H., Mughal, F. P., Hansen, Paul Robert, Holmström, M. O., Fassi, Daniel El , Hasselbalch, H., Skov, V., Kjær, L., Andersen, Mads Hald, Ciplys, E., Slibinskas, R., Fredriksen, Jette Lautrup, Højrup, P. & Houen, G., 2023, In: Current Research in Translational Medicine. 71, 2, 103380.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Physiological response in E. coli to YdgR overexpression depends on whether the protein has an intact function

    Sajid, Salvia, Salas, L. H., Rafiq, M., Lund, T., Jørgensen, M. G., Honoré, B., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, In: Biochemical and Biophysical Research Communications. 661, p. 42-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Substrate space analysis of the bacterial proton-coupled oligopeptide transporter YdgR by cheminformatics

    Sajid, Salvia, Nielsen, M. M. K., Khalil, R., Hansen, Paul Robert, Franzyk, Henrik, Jørgensen, M. G., Christensen, L. P., Mirza, Osman Asghar & Prabhala, B. K., 2023, In: FEMS Microbiology Letters. 370, 9 p., fnad052.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Accepted/In press

    The Y-ome Conundrum: Insights into Uncharacterized Genes and Approaches for Functional Annotation

    Sajid, Salvia, Mashkoor, M., Jørgensen, M. G., Christensen, L. P., Hansen, Paul Robert, Franzyk, Henrik, Mirza, Osman Asghar & Prabhala, B. K., 2023, (Accepted/In press) In: Molecular and Cellular Biochemistry. 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2022
  11. Published

    C-locked analogs of the antimicrobial peptide BP214

    Andersen, I. K. L., Thomsen, T. T., Rashid, J., Bobak, T. R., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2022, In: Antibiotics. 11, 8, 10 p., 1080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cyclic N-Locked Indolicidin Analogues with Antimicrobial Activity: Effect of Ring Size and Fatty Acid Acylation

    Lone, A. B. N., Nielsen, J. E., Thulstrup, Peter Waaben, Lund, R., Hansen, Paul Robert & Jenssen, H., 2022, In: European Journal of Medicinal Chemistry Reports. 6, 7 p., 100080.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Peptide Antibody Reactivity to Homologous Regions in Glutamate Decarboxylase Isoforms and Coxsackievirus B4 P2C

    Trier, N. H., Valdarnini, N., Fanelli, I., Rovero, P., Hansen, Paul Robert, Schafer, C., Ciplys, E., Slibinskas, R., Pociot, F., Friis, T. & Houen, G., 2022, In: International Journal of Molecular Sciences. 23, 8, 16 p., 4424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Production and characterization of peptide antibodies to the C-terminal of frameshifted calreticulin associated with myeloproliferative diseases

    Mughal , F. P., Bergmann , A. C., Huynh , H. U. B., Jørgensen, S. H., Mansha , I., Kesmeh , M., Schürch, P. M., Theocharides, A. P. A., Hansen, Paul Robert, Friis , T., Holmeren , M. Ö., Ciplys , E., Slibinskas , R., Højrup, P., Houen, G. & Trier, N. H., 2022, In: International Journal of Molecular Sciences. 23, 12, 21 p., 6803.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Reactivity of Rheumatoid Arthritis-Associated Citrulline-Dependent Antibodies to Epstein-Barr Virus Nuclear Antigen1-3

    Fanelli, I., Rovero, P., Hansen, Paul Robert, Frederiksen, J. L., Houen, G. & Trier, N. H., 2022, In: Antibodies. 11, 1, 15 p., 20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2021
  17. Published
  18. Published

    Perfluoro-tert-butanol for selective on-resin detritylation: a mild alternative to traditionally used methods

    Wester, A., Hansen, A. M., Hansen, Paul Robert & Franzyk, Henrik, 2021, In: Amino Acids. 53, p. 1455–1466

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Specificity of anti-citrullinated protein antibodies to citrullinated α-enolase peptides as a function of epitope structure and composition

    Fanelli, I., Rovero, P., Hansen, Paul Robert, Fredriksen, Jette Lautrup, Houen, G. & Trier, N. H., 2021, In: Antibodies. 10, 3, 12 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2020
  21. Published
  22. Published

    Alternating Cationic-Hydrophobic Peptide/Peptoid Hybrids: Influence of Hydrophobicity on Antibacterial Activity and Cell Selectivity

    Frederiksen, N., Hansen, Paul Robert, Zabicka, D., Tomczak, M., Urbas, M., Domraceva, I., Björkling, Fredrik & Franzyk, Henrik, 2020, In: ChemMedChem. 15, 24, p. 2544-2561

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Analogues of a Cyclic Antimicrobial Peptide with a Flexible Linker Show Promising Activity Against Pseudomonas aeruginosa and Staphylococcus aureus

    Thomsen, T. T., Mendel, H. C., Al-Mansour, W., Oddo, A., Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: Antibiotics. 9, 7, 13 p., 366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Correlation between hemolytic activity, cytotoxicity and systemic in vivo toxicity of synthetic antimicrobial peptides

    Greco, I., Molchanova, N., Holmedal, E., Jenssen, H., Hummel, B. D., Watts, J. L., Håkansson, J., Hansen, Paul Robert & Svenson, J., 2020, In: Scientific Reports. 10, 13 p., 13206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Fluorescent analogues of Human α-Calcitonin Gene-Related Peptide with vasodilator potency

    Zhu, J., Pedersen, M. D., Ahmed, L. S., Abdolalizadeh, B., Grell, A., Berg, Jais Oliver, Thulstrup, Peter Waaben, Franzyk, Henrik, Edvinsson, L., Sams, A., Sheykhzade, Majid & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences (Online). 21, 4, p. 1-15 15 p., 1343.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Halogenation as a tool to tune antimicrobial activity of peptoids

    Molchanova, N., Nielsen, J. E., Sørensen, K. B., Prabhala, B. K., Hansen, Paul Robert, Lund, R., Barron, A. E. & Jenssen, H., 2020, In: Scientific Reports. 10, 10 p., 14805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Novel Cyclic Lipopeptide Antibiotics: Effects of Acyl Chain Length and Position

    Jensen, S. K., Thomsen, T. T., Oddo, A., Franzyk, Henrik, Løbner-Olesen, Anders & Hansen, Paul Robert, 2020, In: International Journal of Molecular Sciences . 21, 16, 18 p., 5829.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Synthesis of Peptoids Containing MultipleNhtrp andNtrp Residues: A Comparative Study of Resin, Cleavage Conditions and Submonomer Protection

    Lone, A., Arnous, A., Hansen, Paul Robert, Mojsoska, B. & Jenssen, H., 2020, In: Frontiers in Chemistry. 8, 12 p., 370.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2019
  30. Published

    Peptide/Peptoid Hybrid Oligomers: The Influence of Hydrophobicity and Relative Side-Chain Length on Antibacterial Activity and Cell Selectivity

    Frederiksen, N., Hansen, Paul Robert, Björkling, Fredrik & Franzyk, Henrik, 4 Dec 2019, In: Molecules (Print Archive Edition). 24, 18 p., 4429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Peptides, antibodies, peptide antibodies and more

    Trier, N., Hansen, Paul Robert & Houen, G., 11 Nov 2019, In: International Journal of Molecular Sciences (Online). 20, 22 p., 6289.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    A Biophysical Study of the Interactions between the Antimicrobial Peptide Indolicidin and Lipid Model Systems

    Nielsen, J. E., Lind, T. K., Lone, A., Gerelli, Y., Hansen, Paul Robert, Jenssen, H., Cárdenas, M. & Lund, R., 2019, In: B B A - Biomembranes. 1861, 7, p. 1355-1364

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Antimicrobial Activity of α-Peptide/β-Peptoid Lysine-Based Peptidomimetics Against Colistin-Resistant Pseudomonas aeruginosa Isolated From Cystic Fibrosis Patients

    Molchanova, N., Wang, H., Hansen, Paul Robert, Høiby, Niels, Nielsen, Hanne Mørck & Franzyk, Henrik, 2019, In: Frontiers in Microbiology. 10, 9 p., 275.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections

    Greco, I., Emborg, A., Jana, B., Molchanova, N., Oddo, A., Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Scientific Reports. 9, 12 p., 3679.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Fine mapping of glutamate decarboxylase 65 epitopes reveals dependency of hydrophobic amino acids for specific interactions

    Valdarnini, N., Holm, B., Hansen, Paul Robert, Rovero, P., Houen, G. & Trier, N. H., 2019, In: International Journal of Molecular Sciences (Online). 20, 13 p., 2909.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Specificity of anti-citrullinated protein antibodies in rheumatoid arthritis

    Trier, N., Holm, B. E., Hansen, Paul Robert, Slot, O., Locht, H. & Houen, G., 2019, In: Antibodies. 8, 2, 10 p., 37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Structure-Activity Study of an All-D Antimicrobial Octapeptide D2D

    Lone, A., Thomsen, T. T., Nielsen, J. E., Thulstrup, Peter Waaben, Klitgaard, R. N., Løbner-Olesen, Anders, Lund, R., Jenssen, H. & Hansen, Paul Robert, 2019, In: Molecules. 24, 24, 17 p., 4571.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

    Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, Peter Waaben, Damborg, Peter Panduro, Guardabassi, Luca & Hansen, Paul Robert, 2019, In: Molecules. 24, 6, 16 p., 1121.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2018
  40. Published

    Biopolymer nanogels improve antibacterial activity and safety profile of a novel lysine-based α-peptide/β-peptoid peptidomimetic

    Kłodzińska, S. N., Molchanova, N., Franzyk, Henrik, Hansen, Paul Robert, Damborg, Peter Panduro & Nielsen, Hanne Mørck, Jul 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 128, p. 1-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    In Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma

    Greco, I., Hummel, B. D., Vasir, J., Watts, J. L., Koch, J., Hansen, J. E., Nielsen, Hanne Mørck, Damborg, Peter Panduro & Hansen, Paul Robert, 10 Mar 2018, In: Molecules. 23, 3, 15 p., 630.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fluorinated antimicrobial lysine-based peptidomimetics with activity against methicillin-resistant Staphylococcus pseudintermedius

    Molchanova, N., Hansen, Paul Robert, Damborg, Peter Panduro & Franzyk, Henrik, 2018, In: Journal of Peptide Science. 24, 7, 8 p., e3098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

    Karathanasi, G., Bojer, Martin Saxtorph, Baldry, M., Johannessen, B. A., Wolff, S., Greco, I., Kilstrup, M., Hansen, Paul Robert & Ingmer, Hanne, 2018, In: Scientific Reports. 8, 1, 11 p., 3562.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Review on abyssomicins: Inhibitors of the chorismate pathway and folate biosynthesis

    Sadaka, C., Ellsworth, E., Hansen, Paul Robert, Ewin, R., Damborg, Peter Panduro & Watts, J. L., 2018, In: Molecules. 23, 6, 25 p., 1371.

    Research output: Contribution to journalReviewResearchpeer-review

  45. Published

    The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells

    Prabhala, B. K., Aduri, N. G., Sharma, N., Shaheen, A., Sharma, A., Iqbal, M., Hansen, Paul Robert, Brasen, C., Gajhede, Michael, Rahman, M. & Mirza, Osman Asghar, 2018, In: The Journal of Biological Chemistry. 293, p. 1007-1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. 2017
  47. Published

    Advances in development of antimicrobial peptidomimetics as potential drugs

    Molchanova, N., Hansen, Paul Robert & Franzyk, Henrik, 28 Aug 2017, In: Molecules. 22, 9, 60 p., 1430.

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Broadening CD4(+) and CD8(+) T Cell Responses against Hepatitis C Virus by Vaccination with NS3 Overlapping Peptide Panels in Cross-Priming Liposomes

    Filskov, J., Mikkelsen, M., Hansen, Paul Robert, Christensen, Jan Pravsgaard, Thomsen, Allan Randrup, Andersen, P., Bukh, Jens & Agger, E., Jul 2017, In: Journal of Virology. 91, 14, 18 p., e00130-17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Several hPepT1-transported drugs are substrates of the Escherichia coli proton-coupled oligopeptide transporter YdgR

    Prabhala, B. K., Aduri, N. G., Iqbal, M., Rahman, M., Gajhede, Michael, Hansen, Paul Robert & Mirza, Osman Asghar, 16 Feb 2017, In: Research in Microbiology. 168, 5, p. 443-449

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published
  51. 2016
  52. Published

    An amphipathic undecapeptide with all D-amino acids shows promising activity against colistin-resistant strains of Acinetobacter baumannii and a dual mode of action

    Oddo, A., Thomsen, T. T., Kjelstrup, S., Gorey, C., Franzyk, Henrik, Frimodt-Møller, N., Løbner-Olesen, Anders & Hansen, Paul Robert, 2016, In: Antimicrobial Agents and Chemotherapy. 60, 1, p. 592-599 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Modulation of backbone flexibility for effective dissociation of antibacterial and hemolytic activity in cyclic peptides

    Oddo, A., Thomsen, T. T., Britt, H. M., Løbner-Olesen, Anders, Thulstrup, Peter Waaben, Sanderson, J. M. & Hansen, Paul Robert, 2016, In: ACS Medicinal Chemistry Letters. 7, 8, p. 741-745 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2015
  55. Published

    Amphibian antimicrobial peptide fallaxin analogue FL9 affects virulence gene expression and DNA replication in Staphylococcus aureus

    Gottschalk, S., Gottlieb, C. T., Vestergaard, M., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 1 Dec 2015, In: Journal of Medical Microbiology. 64, 12, p. 1504-1513 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Antibodies with specificity for native and denatured forms of ovalbumin differ in reactivity between enzyme-linked immunosorbent assays.

    Holm, B. E., Bergmann, A. C., Hansen, Paul Robert, Koch, C., Houen, G. & Trier, N. H., 1 Feb 2015, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 123, 2, p. 136–145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Contribution of peptide backbone to Anti-citrulline-dependent antibody reactivity

    Trier, N. H., Dam, C., Olsen, D., Hansen, Paul Robert & Houen, G., 2015, In: P L o S One. p. 1-12 12 p., 0144707.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Efficient, regioselective ring-opening of activated aziridine-2-carboxylates with [18F]fluoride

    Schjøth-Eskesen, C., Hansen, Paul Robert, Kjær, Andreas & Gillings, N., 2015, In: ChemistryOpen. 4, 1, p. 65–71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Peptide Macrocycles Featuring a Backbone Secondary Amine: A Convenient Strategy for the Synthesis of Lipidated Cyclic and Bicyclic Peptides on Solid Support

    Oddo, A., Münzker, L. & Hansen, Paul Robert, 2015, In: Organic Letters. 17, 10, p. 2502-2505 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Rational Design of alpha-helical antimicrobial peptides: DOs and DON’Ts

    Uggerhøj, L. E., Poulsen, T. J., Munk, J. K., Fredborg, M., Sondergaard, T. E., Frimodt-Møller, N., Hansen, Paul Robert & Wimmer, R., 2015, In: ChemBioChem. 16, 2, p. 242–253 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The effect of glycine replacement with flexible ω-amino acids on the antimicrobial and haemolytic activity of an amphipathic cyclic heptapeptide

    Oddo, A., Nyberg, N., Frimodt-Møller, N., Thulstrup, Peter Waaben & Hansen, Paul Robert, 2015, In: European Journal of Medicinal Chemistry. 102, p. 574-581 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    [64Cu]-Labelled Trastuzumab: Optimisation of Labelling by DOTA and NODAGA Conjugation and Initial Evaluation in Mice

    Schjøth-Eskesen, C., Nielsen, Carsten Haagen, Heissel, S., Højrup, P., Hansen, Paul Robert, Gillings, N. & Kjær, A., 2015, In: Journal of Labelled Compounds and Radiopharmaceuticals. 58, 6, p. 227-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2014
  64. Published

    Identification and fine mapping of a linear B cell epitope of human vimentin

    Dam, C. E., Houen, G., Hansen, Paul Robert & Trier, N., 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 6, p. 506-514 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Identification of a linear epitope recognized by a monoclonal antibody directed to the heterogeneous nucleoriboprotein A2

    Tronstrøm, J., Dragborg, A. H., Hansen, Paul Robert, Houen, G. & Trier, N. H., 2014, In: Protein and Peptide Letters. 21, 1, p. 25-31 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Novel method to identify the optimal antimicrobial peptide in a combination matrix, using anoplin as an example

    Munk, J., Ritz, C., Fliedner, F. P., Frimodt-Møller, N. & Hansen, Paul Robert, 2014, In: Antimicrobial Agents and Chemotherapy. 58, 2, p. 1063-1070 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation

    Woodworth, J., Aagaard, C., Hansen, Paul Robert, Cassidy, J., Agger, E. M. & Andersen, P., 2014, In: The Journal of Immunology. 192, 7, p. 3247-58

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Structural features of peptoid-peptide hybrids in lipid-water interfaces

    Uggerhøj, L. E., Munk, J. K., Hansen, Paul Robert, Güntert, P. & Wimmer, R., 2014, In: F E B S Letters. 588, 17, p. 3291–3297 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. 2013
  70. Published

    Correlation between centromere protein-F autoantibodies and cancer analyzed by enzyme-linked immunosorbent assay

    Welner, S., Trier, N. H., Morten Frisch, M., Locht, H., Hansen, Paul Robert & Houen, G., 2013, In: Molecular Cancer. 12, 1, 95.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Cyclic peptide inhibitors of the β-sliding clamp in Staphylococcus aureus

    Kjelstrup, S., Hansen, P. M. P., Thomsen, Line Elnif, Hansen, Paul Robert & Løbner-Olesen, Anders, 2013, In: P L o S One. 8, 9, 13 p., e72273.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Identification and mapping of a linear epitope of centromere protein F using monoclonal antibodies

    Welner, S., Trier, N. H., Houen, G. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 2, p. 95-101

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Synthetic analogs of anoplin show improved antimicrobial activities

    Munk, J., Uggerhøj, L. E., Poulsen, T. J., Frimodt-Møller, N., Wimmer, R., Nyberg, N. T. & Hansen, Paul Robert, 2013, In: Journal of Peptide Science. 19, 11, p. 669-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    The antimicrobial lysine-peptoid hybrid LP5 inhibits DNA replication and induces the SOS response in Staphylococcus aureus

    Gottschalk, S., Ifrah, D., Søndergaard, S. L., Gottlieb, C. T., Cohn, M. T., Hiasa, H., Hansen, Paul Robert, Gram, L., Ingmer, Hanne & Thomsen, Line Elnif, 2013, In: B M C Microbiology. 13, 8 p., 192.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. 2012
  76. Published

    Cross-reactivity of a human IgG1 anticitrullinated fibrinogen monoclonal antibody to a citrullinated profilaggrin peptide

    Trier, N. H., Leth, M. L., Hansen, Paul Robert & Houen, G., 31 Dec 2012, In: Protein Science. 21, 12, p. 1929-1941

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Fine mapping of a monoclonal antibody to the N-Methyl D-aspartate receptor reveals a short linear epitope

    Amrutkar, S. D., Trier, N. H., Hansen, Paul Robert & Houen, G., 2012, In: Journal of Peptide Science. 98, 6, p. 567-575 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Identification of continuous epitopes of HuD antibodies related to paraneoplastic diseases/small cell lung cancer

    Trier, N. H., Hansen, Paul Robert, Vedeler, C. A., Somnier, F. E. & Houen, G., 2012, In: Journal of Neuroimmunology. 243, 1, p. 25-33 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Production and characterization of peptide antibodies

    Trier, N. H., Hansen, Paul Robert & Houen, G., 2012, In: Methods. 56, 2, p. 136-144 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. 2011
  81. Published

    Evaluation of 4-[18F]fluorobenzoyl-FALGEA-NH2 as a positron emission tomography tracer for epidermal growth factor receptor mutation variant III imaging in cancer

    Denholt, C. L., Binderup, Tina, Stockhausen, M., Poulsen, H. S., Spang-Thomsen, M., Hansen, Paul Robert, Gillings, N. M. & Kjær, Andreas, 2011, In: Nuclear Medicine and Biology. 38, 4, p. 509-515 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Fast and efficient characterization of an anti-gliadin monoclonal antibody epitope related to celiac disease using resin-bound peptides

    Petersen, N. H., Hansen, Paul Robert & Houen, G., 2011, In: Journal of Immunological Methods. 365, 1-2, p. 174-182 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    The interaction between calreticulin and immunoglobulin G and immunoglobulin Y

    Møllegaard, K. M., Duus, K., Træholt, S. D., Thaysen-Andersen, M., Liu, Y., Palma, A. S., Feizi, T., Hansen, Paul Robert, Højrup, P. & Houen, G., 2011, In: B B A - Proteins and Proteomics. 1814, 7, p. 889-899 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. 2010
  85. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  86. Published

    Antimicrobial activity of small 3-(2 naphthyl)-L-alanine containing peptides

    Hansen, Paul Robert & Frimodt-Møller, N., 2010, In: Proceedings of the 31st European Peptide Symposium,. 2 p.

    Research output: Contribution to journalConference articleResearch

  87. Published

    Complex metabolism of aromatic glucosinolates in Pieris rapae caterpillars involving nitrile formation, hydroxylation, demethylation, sulfation, and host plant dependent carboxylic acid formation

    Agerbirk, Niels, Olsen, C. E., Poulsen, E., Jacobsen, Niels & Hansen, Paul Robert, 2010, In: Insect Biochemistry and Molecular Biology. 40, 2, p. 126-137 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Fluorine-18 labelling of a series of potential EGFRvIII targeting peptides with a parallel labelling approach using [18F]FPyME

    Denholt, C. L., Kuhnast, B., Dollé, F., Hinnen, F., Hansen, Paul Robert, Gillings, N. & Kjær, A., 2010, In: Journal of Labelled Compounds and Radiopharmaceuticals. 53, 13, p. 774-778 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. 2009
  90. Published

    Interaction of the chaperone calreticulin with proteins and peptides of different structural classes

    Duus, K., Sandhu, N., Jørgensen, Carsten, Hansen, Paul Robert, Steinø, A., Thaysen-Andersen, M., Højrup, P. & Houen, G., 1 Nov 2009, In: Protein and Peptide Letters. 16, 11, p. 1414-1423 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Comparison of [18F]FBA and [18F]FPyMe as peptide radiolabeling agents of PEPHC1 for PET imaging of EGFRvIII

    Hansen, C. L., Kuhnast, B., Hinnen, F., Dollé, F., Gillings, N., Hansen, Paul Robert & Kjær, Andreas, 2009, In: Advances in Experimental Medicine and Biology. 611, p. 405-6 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library

    Denholt, C. L., Hansen, Paul Robert, Pedersen, N., Poulsen, H. S., Gillings, N., Kjær, Andreas, Denholt, C. L., Hansen, P. R., Pedersen, N., Poulsen, H. S., Gillings, N. & Kjær, Andreas, 2009, In: Biopolymers. 91, 3, p. 201-6 6 p.

    Research output: Contribution to journalJournal articleResearch

  93. Published

    Peptoid analogues of anoplin show antibacterial activity

    Meinike, K. & Hansen, Paul Robert, 2009, In: Protein and Peptide Letters. 16, 9, p. 1006-1011 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. 2008
  95. Published

    Sinapis phylogeny and evolution of glucosinolates and specific nitrile degrading enzymes

    Agerbirk, Niels, Warwick, S. I., Hansen, Paul Robert & Olsen, C. E., 2008, In: Phytochemistry. 69, 17, p. 2937-2949 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Antigenic profiling of a Chlamydia trachomatis gene-expression library

    Folmann, F., Olsen, A. W., Jensen, K. T., Hansen, Paul Robert, Andersen, P. & Theisen, M., 2008, In: Journal of Infectious Diseases. 197, p. 897-905 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Antimicrobial activities of twenty lysine-peptoid hybrids against clinically relevant bacteria and fungi

    Ryge, T. S., Frimodt-Møller, N. & Hansen, Paul Robert, 2008, In: Chemotherapy. 54, 2, p. 152-156 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Identification of amino acid residues in PEPHC1 important for binding to the tumor-specific receptor EGFRvIII

    Hansen, C. L., Hansen, Paul Robert, Pedersen, N., Poulsen, H. S., Gillings, N. & Kjær, Andreas, 2008, In: Chemical Biology and Drug Design (Print). 72, 4, p. 273-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Interaction of calreticulin with amyloid beta peptide 1-42

    Duus, K., Hansen, Paul Robert & Houen, G., 2008, In: Protein and Peptide Letters. 15, 1, p. 103-107 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    The chaperone and potential mannan-binding lectin (MBL) co-receptor calreticulin interacts with MBL through the binding site for MBL-associated serine proteases

    Pagh, R., Duus, K., Laursen, I., Hansen, Paul Robert, Mangor, J., Thielens, N., Arlaud, G. J., Kongerslev, L., Højrup, P. & Houen, G., 2008, In: FEBS Journal. 275, 3, p. 515-526 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. 2007
  102. Published

    Peptide binding specificity of the chaperone calreticulin

    Sandhu, N., Duus, K., Jørgensen, C. S., Hansen, Paul Robert, Bruun, S. W., Pedersen, L. Ø., Højrup, P. & Houen, G., 2007, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1774, 6, p. 701-713 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Second-generation nanofiltered plasma-derived mannan-binding lectin product: process and characteristics

    Laursen, I., Houen, G., Højrup, P., Brouwer, N., Krogsøe, L. B., Blou, L. & Hansen, Paul Robert, 2007, In: Vox Sanguinis. 92, 4, p. 338-350 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Structure-activity study of the antibacterial peptide fallaxin

    Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. 2006
  106. Published

    Potent antibacterial lysine-peptoid hybrids identified from a positional scanning combinatorial library

    Ryge, T. S. & Hansen, Paul Robert, 2006, In: Bioorganic & Medicinal Chemistry. 14, 13, p. 4444-4451 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. 2005
  108. Published

    Novel lysine-peptoid hybrids with antibacterial properties

    Ryge, T. S. & Hansen, Paul Robert, 2005, In: Journal of Peptide Science. 11, 11, p. 727-734 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Structure-activity relationship study of anoplin

    Ifrah, D., Doisy, X., Ryge, T. S. & Hansen, Paul Robert, 2005, In: Journal of Peptide Science. 11, p. 113-121 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    bdrF2 of lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection

    Zhang, H., Raji, A., Theisen, M., Hansen, Paul Robert & Marconi, R. T., 2005, In: Journal of Bacteriology. 187, 1, p. 175-184 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. 2004
  112. Published

    Monomeric analogues of halocidin

    Doisy, X., Ifrah, D. & Hansen, Paul Robert, 2004, In: Organic and Biomolecular Chemistry. 2, 19, p. 2757-2762 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    New indolicidin analogues with potent antibacterial activity

    Neerup, T. S. R., Doisy, X., Ifrah, D., Olsen, John Elmerdahl & Hansen, Paul Robert, 2004, In: Chemical Biology and Drug Design (Print). 64, 5, p. 171-185 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. 2003
  115. Published

    Analysis of the OspE determinants involved in binding of factor H and OspE-targeting antibodies elicited during Borrelia burgdorferi infection in mice

    Metts, M. S., McDowell, J. V., Theisen, Michael, Hansen, Paul Robert & Marconi, R. T., 1 Jun 2003, In: Infection and Immunity. 71, 6, p. 3587-3596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Analysis of the OspE determinants involved in the binding of factor H and OspE targeting antibodies elicited during infection in mice

    Metts, M. S., McDowell, J. V., Theisen, M., Hansen, Paul Robert & Marconi, R. T., 2003, In: Infection and Immunity. 71, p. 3587-3596 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Preparation of bioconjugates by solid-phase conjugation to ion exchange matrix-adsorbed carrier proteins

    Houen, G., Olsen, D. T., Hansen, Paul Robert, Petersen, K. B. & Barkholt, V., 2003, In: Bioconjugate Chemistry. 14, 1, p. 75-79 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. 2002
  119. Published

    Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

    Litman, Thomas, Jensen, U., Hansen, Alastair, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 20 Sep 2002, In: BBA General Subjects. 1565, 1, p. 6-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Kemi for tiden: peptider og peptidbiblioteker

    Hansen, Paul Robert, 2002, In: Dansk Kemi. 83, 4, p. 25 1 p.

    Research output: Contribution to journalJournal articleResearch

  121. Published

    Secondary structure and association of melittin during and after solid-phase synthesis: a Raman and static light scattering study

    Lund Hansen, C., Hansen, Paul Robert, Callisen, T. H., Bauer, R. & Faurskov Nielsen, O., 2002, In: Journal of Raman Spectroscopy. 33, 3, p. 142-146 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Use of peptide antibodies to probe for the mitoxantrone resistance-associated protein MXR/BCRP/ABCP/ABCG2

    Litman, T., Jensen, U., Hansen, Axel Kornerup, Covitz, K., Zhan, Z., Fetsch, P., Abati, A., Hansen, Paul Robert, Horn, T., Skovsgaard, T. & Bates, S. E., 2002, In: Biochimica et Biophysica Acta - Biomembranes. 1565, 1, p. 6-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  123. 2000
  124. Published

    Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen

    Weinreich Olsen, A., Hansen, Paul Robert, Holm, A. & Andersen, P., 2000, In: European Journal of Immunology. 30, p. 1724-1732 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. 1998
  126. Published

    A ¤new method for the synthesis of neoglycopeptides

    Hansen, Paul Robert, Olsen, C. E. & Holm, A., 1998, In: Bioconjugate Chemistry. 9, 1, p. 126-131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. 1996
  128. Published

    Photochemical conjugation of peptides to carrier proteins using 1,2, 3-thiadiazole-4-carboxylic acid: immunoreactivity of free C-terminal epitope with specific antibodies

    Hansen, Paul Robert, Flyge, H., Holm, A., Lauritzen, E. & Larsen, B. D., 1996, In: International Journal of Peptide and Protein Research. 47, p. 419-426 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. Published

    Synthesis of 2-acetamido-2-deoxy- beta-D-glucopyranose O-glycopeptides from N-dithiasuccinoyl-protected derivatives

    Jensen, Knud Jørgen, Hansen, Paul Robert, Venugopal, D. & Barany, G., 1996, In: Journal of the American Chemical Society. 118, 13, p. 3148-3155 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. 1995
  131. Published

    Solid-phase synthesis of O-glycopeptides from N-dithiasuccinoyl-protected D-glucosamine derivatives

    Hansen, Paul Robert, Jensen, Knud Jørgen & Barany, G., 1995, In: Peptides. 1994, p. 729-730 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. 1994
  133. Published

    A quantitative assay to measure the interaction between immunogenic peptides and purified class I major histocompatibility complex molecules

    Olsen, A. C., Pedersen, L. O., Hansen, A. S., Buus, Søren, Nissen, Mogens Holst, Olsen, M., Hansen, Paul Robert & Holm, A., 1994, In: European Journal of Immunology. 24, 2, p. 385-92 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4237511