Søren Brøgger Christensen
Professor emeritus, Professor, emeritus
- 2012
- Published
Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: New strategies going beyond the standard
Kongstad, Kenneth Thermann, Ebild, S. J., Christensen, Søren Brøgger, Godejohann, M. & Jaroszewski, J. W., 28 Dec 2012, In: Journal of Chromatography A. 1270, p. 171-177 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
6-O-Methylkrigeine, a new Amaryllidaceae alkaloid from Nerine huttoniae Schönland
Molander, M., Christensen, Søren Brøgger, Jaeger, A. K., Olsen, C. E. & Rønsted, Nina, 2012, In: Natural Product Research. 26, 1, p. 56-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae
Rønsted, Nina, Symonds, M. R. E., Birkholm, T., Christensen, Søren Brøgger, Meerow, A. W., Schmidt, M. M., Mølgaard, Per, Petersen, G., Rasmussen, N., van Staden, J., Stafford, G. I. & Jäger, A., 14 Sep 2012, In: BMC Evolutionary Biology. 12, 12 p., 182.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Amaryllidaceae alkaloids from Rauhia multiflora (Kunth) Ravenna
Birkholm, T., Rasmussen, N., Christensen, Søren Brøgger, Jäger, A. & Rønsted, Nina, Aug 2011, In: Planta Medica. 77, 12, PG12.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Drugs for the neglected disease malaria based on natural products
Christensen, Søren Brøgger & Bygbjerg, Ib Christian, 1 Jan 2011, Bioactive Compounds from Natural Sources: Natural Products as Lead Compounds in Drug Discovery, Second Edition. CRC Press, p. 525-550 26 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump
Mahmmoud, Y. A. & Christensen, Søren Brøgger, Oct 2011, In: BBA General Subjects. 1808, 10, p. 2413-2420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.)
Saaby, Lasse, Jäger, A. K., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Feb 2011, In: Phytotherapy Research. 25, 2, p. 195-201Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amaryllidaceae alkaloids from the Australasian tribe Calostemmateae with acetylcholinesterase inhibitory activity
Søvsø Jensen, B., Christensen, Søren Brøgger, Jäger, A. K. & Rønsted, Nina, Apr 2011, In: Biochemical Systematics and Ecology. 39, 2, p. 153-155Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thapsigargin affinity purification of intracellular P2A-type Ca2+ ATPases
Vandecaetsbeek, I., Christensen, Søren Brøgger, Liu, Huizhen, van Veldhoven, P. P., Waelkens, E., Eggermont, J., Raeymaekers, L., Møller, J. V., Nissen, P., Wuytack, F. & Vangheluwe, P., 1 May 2011, In: BBA General Subjects. 1813, 5, p. 1118-1127Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1
Bach, Anders, Stuhr-Hansen, N., Thorsen, T. S., Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In: Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neglected diseases
Christensen, Søren Brøgger, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 341-358Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
The pharmacophore of thapsigargin
Christensen, Søren Brøgger, Skytte, D. M., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M. & Møller, J. V., Aug 2010, In: Planta Medica. 76, 12, p. 1187Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A phenylpropanoid, a slovenolide, two sulphur-containing germacranes and Ca+2-ATPase inhibitors from Thapsia villosa
Rubal, J. J., Moreno-Dorado, F. J., Guerra, F. M., Jorge, Z. D., Galán, M. D. C., Salido, G. M., Christensen, Søren Brøgger, Søhoel, H. & Massanet, G. M., 2010, In: Planta Medica. 76, 3, p. 284-290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Planternes slægtskab som skattekort til nye lægemidler
Rønsted, Nina, Larsen, Birger Brodin, Christensen, Søren Brøgger, Eriksson, A. H. & Jäger, A. K., Dec 2010, In: Lægemiddelforskning. 2010, p. 19-21Research output: Contribution to journal › Journal article › Communication
- Published
Characterization of anti-inflammatory triterpene acids from rose hip powder (Rosa canina L.)
Saaby, Lasse, Jäger, A., Moesby, L., Hansen, E. W. & Christensen, Søren Brøgger, Aug 2010, In: Planta Medica. 76, 12, p. 1171Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Elucidation of the topography of the thapsigargin binding site in the sarco-endoplasmic calcium ATPase
Skytte, D. M., Møller, J. V., Liu, Huizhen, Nielsen, H. Ø., Svenningsen, L. E., Jensen, C. M., Olsen, C. E. & Christensen, Søren Brøgger, 2010, In: Bioorganic & Medicinal Chemistry. 18, 15, p. 5634-5646 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
Winther, A. L., Liu, Huizhen, Sonntag, Y., Olesen, C., le Maire, M., Søhoel, H., Olsen, C. E., Christensen, Søren Brøgger, Nissen, P. & Møller, J. V., 2010, In: Journal of Biological Chemistry. 285, 37, p. 28883-28892Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
A Trojan horse in drug development: targeting of thapsigargins towards prostate cancer cells
Christensen, Søren Brøgger, Skytte, D. M., Denmeade, S. R., Dionne, C., Møller, J. V., Nissen, P. & Isaacs, J. T., 2009, In: Anti-Cancer Agents in Medicinal Chemistry. 9, 3, p. 276-294Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells
Griend, D. J. V., Antony, L., Dalrymple, S. L., Xu, Y., Christensen, Søren Brøgger, Denmeade, S. R. & Isaacs, J. T., 2009, In: Molecular Cancer Therapeutics. 8, 5, p. 1340-1349Research output: Contribution to journal › Journal article › Research › peer-review
- Published
19a-hydroxy-3-oxo-ursa-1,12-dien-28-oic acid, an antiplasmodial triterpenoid isolated from Canthium multiflorum
Traore, M., Ziegler, H. L., Olsen, C. E., Hassanata, M., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2009, In: Natural Product Research. 23, 12, p. 1108-1111 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopies
Jalkanen, K. J., Gale, J. D., Lassen, P. R., Hemmingsen, Lars Bo Stegeager, Rodarte, A., Degtyarenko, I. M., Nieminen, R. M., Knapp-Mohammady, M., Suhai, S. & Christensen, Søren Brøgger, 2008, In: Theoretical Chemistry Accounts. 119, 1-3, p. 177-190 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lægemidler fra naturstoffer: fortid eller fremtid?
Jaroszewski, J. W., Christensen, Søren Brøgger, Franzyk, Henrik, Stærk, Dan & Ziegler, H., 2008, In: Lægemiddelforskning. p. 4-6Research output: Contribution to journal › Journal article › Communication
- Published
Isolation of linoleic and alpha-linolenic acids as COX-1 and -2 inhibitors in rose hip
Jäger, A., Petersen, K. N., Thomasen, G. & Christensen, Søren Brøgger, 2008, In: Phytotherapy Research. 22, 7, p. 982-984 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation of the MAO-inhibitor naringenin from Mentha aquatica L
Olsen, H. T., Stafford, G. I., van Staden, J., Christensen, Søren Brøgger & Jäger, A. K., 2008, In: Journal of Ethnopharmacology. 117, 3, p. 500-502Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioassay-guided identification and isolation of anticancer components in Hypholoma fasciculare extract
Pang, W. S. K., Chen, M., Zhai, L. & Christensen, Søren Brøgger, 2008.Research output: Contribution to conference › Poster › Research
ID: 1300951
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The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed
Research output: Contribution to journal › Journal article › Research › peer-review
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341
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Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae
Research output: Contribution to journal › Journal article › Research › peer-review
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306
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Demethoxycurcumin is a potent inhibitor of P-type ATPases from diverse kingdoms of life
Research output: Contribution to journal › Journal article › Research › peer-review
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