Søren Brøgger Christensen

Søren Brøgger Christensen

Professor emeritus, Professor, emeritus

Member of:

    ORCID: 0000-0002-5773-6874

    Publication year:
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    51 - 100 out of 182Page size: 50
    1. 1994
    2. Published

      Ca2+-ATPase inhibitory activity of a locked analogue of thapsigargin

      Christensen, Søren Brøgger, Olsen, C. E., Moldt, P., Cornett, Claus, Poulsen, J. J., Treiman, M. & Andersen, A., 1994, In: Bioorganic & Medicinal Chemistry Letters.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection

      Chen, M., Theander, Thor Grundtvig, Christensen, Søren Brøgger, Hviid, Lars, Zhai, L. & Kharazmi, A., 1994, In: Antimicrobial Agents and Chemotherapy. 38, 7, p. 1470-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Molluscicidal saponins from a Zimbabwean strain of Phytolacca dodecandra

      Thiilborg, S. T., Christensen, Søren Brøgger, Cornett, Claus, Olsen, C. E. & Lemmich, E., 1994, In: Phytochemistry. 36, 3, p. 753-759 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      SELECTIVE TRANSFORMATIONS OF THE CA-2+ PUMP INHIBITOR THAPSIGARGIN

      Andersen, A., Cornett, Claus, Lauridsen, A., Olsen, C. E. & Christensen, Søren Brøgger, 1994, In: Acta Chemica Scandinavica. Supplementum. 48, 4, p. 340-346 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Thapsigargin: a novel molecular probe for studying intracellular calcium release and storage

      Thastrup, Ole, Dawson, A. P., Scharff, O., Foder, B., Cullen, P. J., Drøbak, B. K., Bjerrum, P. J., Christensen, Søren Brøgger & Hanley, M. R., 1994, In: Agents and Actions. 43, 3-4, p. 187-93 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 1995
    8. Published

      Structure-activity relationships of analogues of thapsigargin modified at O-11 and O-12

      Nielsen, S. F., Thastrup, Ole, Pedersen, R., Olsen, C. E. & Christensen, Søren Brøgger, 1995, In: Journal of Medicinal Chemistry. 38, 2, p. 272-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Synthesis of antiparasitic licorice chalcones

      Nielsen, S. F., Chen, M., Theander, Thor Grundtvig, Kharazmi, A. & Christensen, Søren Brøgger, 1995, In: Bioorganic & Medicinal Chemistry Letters. 5, p. 449-452 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria

      Zhai, L., Blom, J., Chen, M., Christensen, Søren Brøgger & Kharazmi, A., 1995, In: Antimicrobial Agents and Chemotherapy. 39, 12, p. 2742-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 1996
    12. Published

      Syntheses of 11-hydroxylated guaianolides

      Lauridsen, A., Cornett, Claus, Vulpius, T., Moldt, P. & Christensen, Søren Brøgger, 1996, In: Acta Chemica Scandinavica. Supplementum. 50, 2, p. 150-157 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. 1997
    14. Published

      Discovery of oxygenated chalcoes as novel antimalarial agents

      Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Discovery of oxygentade chalcones as novel antimalarial agents

      Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Sesquiterpenoids from Thapsia species and medicinal chemistry of the thapsigargins.

      Christensen, Søren Brøgger, Andersen, A. & Smitt, U. W., 1997, In: Fortschritte der Chemie organischer Naturstoffe. Progress in the chemistry of organic natural products. Progrès dans la chimie des substances organiques naturelles. 71, p. 129-167 39 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      Synthesis, isolation and identification of glucuronides and mercapturic acids of a novel antiparasitic agent, licochalcone A

      Nadelmann, L., Tjornelund, J., Hansen, S. H., Cornett, Claus, Sidelmann, U. G., Braumann, U., Christensen, E. & Christensen, Søren Brøgger, 1997, In: Xenobiotica. 27, 7, p. 667-680 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      The novel oxygenated chalcone, 2,4-dimethoxy-4'-butoxychalcone, exhibits potent activity against human malaria parasite Plasmodium falciparum in vitro and rodent parasites Plasmodium berghei and Plasmodium yoelii in vivo

      Chen, M., Christensen, Søren Brøgger, Zhai, L., Rasmussen, M. H., Theander, Thor Grundtvig, Frøkjær, Sven, Steffansen, B., Davidsen, J. & Kharazmi, A., 1997, In: Journal of Infectious Diseases. 176, 5, p. 1327-33 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Two new antiprotozoal 5-methylcoumarins from Vernonia brachycalyx

      Oketch-Rabah, H. A., Lemmich, E., Dossaji, S. F., Theander, Thor Grundtvig, Olsen, C. E., Cornett, Claus, Kharazmi, A. & Christensen, Søren Brøgger, 1997, In: Journal of Natural Products. 60, 5, p. 458-61 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. 1998
    21. Published

      Alkamides from Phyllanthus fraternus

      Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Antiprotozoal properties of 16,17-dihydrobrachycalyxolide from Vernonia brachycalyx

      Oketch-Rabah, H. A., Christensen, Søren Brøgger, Frydenvang, Karla Andrea, Dossaji, S. F., Theander, Thor Grundtvig, Cornett, Claus, Watkins, W. M., Kharazmi, A. & Lemmich, E., 1998, In: Planta Medica. 64, 6, p. 559-62 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Limonoids from Khaya senegalensis

      Khalid, S., Friedrichsen, G., Kharazmi, A., Theander, Thor Grundtvig, Olsen, C. & Christensen, Søren Brøgger, 1998, In: Phytochemistry. 49, 6, p. 1769-1772 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Modifications of the alpha,beta-double bond in chalcones only marginally affect the antiprotozoal activities

      Nielsen, S. F., Kharazmi, A. & Christensen, Søren Brøgger, 1998, In: Bioorganic & Medicinal Chemistry. 6, 7, p. 937-45 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      A tool coming of age: Thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases

      Treiman, M., Caspersen, C. & Christensen, Søren Brøgger, 1 Jan 1998, In: Trends in Pharmacological Sciences. 19, 4, p. 131-135 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 1999
    27. Published

      Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida

      Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars, Kharazmi, A., Nkrumah, F. K. & Christensen, Søren Brøgger, 1999, In: Planta Medica. 65, 3, p. 259-61 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      The antileishmanial activity of novel oxygenated chalcones and their mechanism of action

      Zhai, L., Chen, M., Blom, J., Theander, Thor Grundtvig, Christensen, Søren Brøgger & Kharazmi, A., 1999, In: Journal of Antimicrobial Chemotherapy. 43, 6, p. 793-803 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. 2000
    30. Published

      Absolute configuration and antiprotozoal activity of minquartynoic acid

      Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P., Kharazmi, A. & Huansi, A. G., 2000, In: Journal of Natural Products. 63, 9, p. 1295-6 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      A simple and efficient separation of the curcumins, the antiprotozoal constituents of Curcuma longa

      Rasmussen, H. B., Christensen, Søren Brøgger, Kvist, L. P. & Karazmi, A., 22 Jun 2000, In: Planta Medica. 66, 4, p. 396-398 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. 2001
    33. Published

      Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones

      Chen, M., Zhai, L., Christensen, Søren Brøgger, Theander, Thor Grundtvig & Kharazmi, A., 2001, In: Antimicrobial Agents and Chemotherapy. 45, 7, p. 2023-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Isolation of tow high-polar fractions from 'Banlangen', root of isatis tinctoria L. and its activity

      Qin, Q., He, H. P., Christensen, Søren Brøgger, Rasmussen, H. B., Kharazmi, A. & Chen, M., 1 Jan 2001, In: Chinese Pharmacological Bulletin. 17, 6, p. 714-715 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. 2002
    36. Published

      Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus)

      Jensen, H. D., Krogfelt, K. A., Cornett, Claus, Hansen, S. H. & Christensen, Søren Brøgger, 2002, In: Journal of Agricultural and Food Chemistry. 50, 23, p. 6871-4 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Incorporation of the Cross Fire Beilstein database in the organic chemistry curriculum at the Royal Danish School of Pharmacy

      Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 2002, In: Journal of Chemical Education. 79, p. 765-768

      Research output: Contribution to journal › Journal article › Research

    38. Published

      Incorporation of the crossfire Beilstein database into the organic chemistry curriculum at the Royal Danish School of Pharmacy

      Christensen, Søren Brøgger, Franzyk, Henrik, Frølund, Bente, Jaroszewski, J. W., Stærk, Dan & Vedsø, P., 1 Jun 2002, In: Journal of Chemical Education. 79, 6, 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      An antiplasmodial lignan from Euterpe precatoria

      Jensen, J. F., Kvist, L. P. & Christensen, Søren Brøgger, 1 Dec 2002, In: Journal of Natural Products. 65, 12, p. 1915-1917 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. 2003
    41. Published

      Ancistrotanzanine A, the first 5,3’-coupled naphtylisoquinoline alkaloid, and two further, 5,8’-linked related compounds from the newly described species Ancistrocladus tanzaniensis

      Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R., Reichert, M., Maksimenka, K. & Christensen, Søren Brøgger, 2003, In: Journal of Natural Products. 66, p. 1159-1165

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro

      Larsen, Erik, Kharazmi, A., Christensen, L. P. & Christensen, Søren Brøgger, 1 Jul 2003, In: Journal of Natural Products. 66, 7, p. 994-995 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer

      Denmeade, S. R., Jakobsen, C. M., Janssen, S., Khan, S. R., Garrett, E. S., Lilja, H., Christensen, Søren Brøgger & Isaacs, J. T., 2 Jul 2003, In: National Cancer Institute. Journal (Online). 95, 13, p. 990-1000 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. 2004
    45. Published

      Ancistrotanzanine C and related 5,1’- and 7,3’- coupled naphtylisoquinoline alkaloids from Ancistrocladus tanzaniensis

      Bringmann, G., Dreyer, M., Faber, J. H., Dalsgaard, P. W., Stærk, Dan, Jaroszewski, J. W., Ndangalasi, H., Mbago, F., Brun, R. & Christensen, Søren Brøgger, 2004, In: Journal of Natural Products. 67, p. 743-748

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      The antiparasitic compound Licochalcon A is a potent echinocytogenic agent that modifies erythrocyte membrane in the concentration region where the antiplasmodial activity is observed

      Ziegler, H. L., Hansen, Harald S., Stærk, Dan, Christensen, Søren Brøgger, Hägerstrand, H. & Jaroszewski, J. W., 2004, In: Antimicrobial Agents and Chemotherapy. 48, p. 4067-4071

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Antiplasmodial Constituents of Cajanus cajan

      Duker-Eshun, G., Jaroszewski, J. W., Asomaning, W. A., Oppong-Boachie, F. & Christensen, Søren Brøgger, 1 Feb 2004, In: Phytotherapy Research. 18, 2, p. 128-130 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Synthesis of the thapsigargins

      Ley, S. V., Antonello, A., Balskus, E. P., Booth, D. T., Christensen, Søren Brøgger, Cleator, E., Gold, H., Högenauer, K., Hünger, U., Myers, R. M., Oliver, S. F., Simic, O., Smith, M. D., Søhoel, H. & Woolford, A. J. A., 17 Aug 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 33, p. 12073-12078 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Screening a combinatorial peptide library to develop a human glandular kallikrein 2-activated prodrug as targeted therapy for prostate cancer

      Janssen, S., Jakobsen, C. M., Rosen, D. M., Ricklis, R. M., Reineke, U., Christensen, Søren Brøgger, Lilja, H. & Denmeade, S. R., 1 Nov 2004, In: Molecular Cancer Therapeutics. 3, 11, p. 1439-1450 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. 2005
    51. Published

      Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase

      Singh, P., Mhaka, A. M., Christensen, Søren Brøgger, Gray, J. J., Denmeade, S. R. & Isaacs, J. T., 21 Apr 2005, In: Journal of Medicinal Chemistry. 48, 8, p. 3005-3014 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. 2006
    53. Published

      Cytotoxic phenylpropanoids and an additional thapsigargin analogue isolated from Thapsia garganica

      Liu, Huizhen, Jensen, K. G., Tran, L. M., Chen, M., Zhai, L., Olsen, C. E., Søhoel, H., Denmeade, S. R., Issacs, J. T. & Christensen, Søren Brøgger, 2006, In: Phytochemistry. 67, 24, p. 2651-2658 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Sesquiterpenes from Thapsia nitida var. meridionalis and Thapsia nitida var. nitida

      Rubal, J. J., Guerra, F. M., Moreno-Dorado, F. J., Jorge, Z. D., Massanet, G. M., Søhoel, H., Smitt, U. W., Frydenvang, Karla Andrea, Christensen, Søren Brøgger, Nielsen, C. & Eriksson, M., 2006, In: Journal of Natural Products. 69, 11, p. 1566-71 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug

      Janssen, S., Rosen, D. M., Ricklis, R. M., Dionne, C. A., Lilja, H., Christensen, Søren Brøgger, Isaacs, J. T. & Denmeade, S. R., 1 Mar 2006, In: Prostate. 66, 4, p. 358-368 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis

      Kvist, L. P., Christensen, Søren Brøgger, Rasmussen, H. B., Mejia, K. & Gonzalez, Ana Valeria, 19 Jul 2006, In: Journal of Ethnopharmacology. 106, 3, p. 390-402 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Ancistrocladinium A and B, the first N,C-coupled naphthyldihydroisoquinoline alkaloids, from a Congolese Ancistrocladus species

      Bringmann, G., Kajahn, I., Reichert, M., Pedersen, S. E. H., Faber, J. H., Gulder, T., Brun, R., Christensen, Søren Brøgger, Ponte-Sucre, A., Moll, H., Heubl, G. & Mudogo, V., 8 Dec 2006, In: Journal of Organic Chemistry. 71, 25, p. 9348-9356 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. 2007
    59. Published

      Cytotoxic kurubasch aldehyde from Trichilia emetica

      Traore, M., Zhai, L., Chen, M., Olsen, C. E., Odile, N., Pierres, G. I., Bosco, O. J., Robert, G. T. & Christensen, Søren Brøgger, 2007, In: Natural Product Reports. 21, 1, p. 13-17

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Identification of natural products using HPLC-SPE combined with CapNMR

      Lambert, M., Wolfender, J., Stærk, Dan, Christensen, Søren Brøgger, Hostettmann, K. & Jaroszewski, J. W., 2007, In: Analytical Chemistry. 79, 2, p. 727-735

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Isolation and characterization of pristimerin as the antiplasmodial and antileishmanial agent of Maytenus senegalensis (Lam.) Exell.

      Khalid, S. A., Friedrichsen, G. M., Christensen, Søren Brøgger, El Tahir, A. & Satti, G. M., 2007, In: Arkivoc. ix, p. 129-134

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Noter til bioorganisk kemi M23-1

      Franzyk, Henrik, Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, København: Københavns Universitet, Det Farmaceutiske Fakultet, Institut for Medicinalkemi.

      Research output: Book/Report › Compendium/lecture notes › Education

    63. Published

      Prenylated acetophenones from Melicope obscura and Melicope obtusifolia ssp. obtusifolia var. arborea and their distribution in Rutaceae

      Adsersen, A., Smitt, U. W., Simonsen, H. T., Christensen, Søren Brøgger & Jaroszewski, J. W., 2007, In: Biochemical Systematics and Ecology. 35, 7, p. 447-453

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Psychotropic constituents of Mentha aquatica L.

      van Staden, J., Stafford, G. I., Almqvist, J. P., Vangsøe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A. & Jäger, A. K., 2007.

      Research output: Contribution to conference › Poster › Research

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    ID: 1300951