Synthesis of the thapsigargins
Research output: Contribution to journal › Journal article › Research › peer-review
The thapsigargins are a family of complex guaianolides with potent and selective Ca2+-modulating properties. This article documents the evolution of a synthetic route through several iterations to a final practical and scaleable synthetic route capable of generating both unnatural and natural products based around the guaianolide skeleton.
Original language | English |
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Journal | Proceedings of the National Academy of Sciences of the United States of America |
Volume | 101 |
Issue number | 33 |
Pages (from-to) | 12073-12078 |
Number of pages | 6 |
ISSN | 0027-8424 |
DOIs | |
Publication status | Published - 17 Aug 2004 |
ID: 232596272