Stephan Pless

Stephan Pless

Professor

ORCID: 0000-0001-6654-114X

Publication year:
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1 - 25 out of 79Page size: 25
  1. 2007
  2. Published

    Conformational variability of the glycine receptor M2 domain in response to activation by different agonists

    Pless, Stephan, Dibas, M. I., Lester, H. A. & Lynch, J. W., 7 Dec 2007, In: The Journal of Biological Chemistry. 282, 49, p. 36057-67 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2008
  4. Published

    Illuminating the structure and function of Cys-loop receptors

    Pless, Stephan & Lynch, J. W., Oct 2008, In: Clinical and Experimental Pharmacology & Physiology (Online). 35, 10, p. 1137-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue

    Pless, Stephan, Millen, K. S., Hanek, A. P., Lynch, J. W., Lester, H. A., Lummis, S. C. R. & Dougherty, D. A., 22 Oct 2008, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 28, 43, p. 10937-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2009
  7. Published

    Distinct conformational changes in activated agonist-bound and agonist-free glycine receptor subunits

    Pless, Stephan & Lynch, J. W., Mar 2009, In: Journal of Neurochemistry. 108, 6, p. 1585-94 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain

    Pless, Stephan & Lynch, J. W., 5 Jun 2009, In: The Journal of Biological Chemistry. 284, 23, p. 15847-56 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy

    Pless, Stephan & Lynch, J. W., 2 Oct 2009, In: The Journal of Biological Chemistry. 284, 40, p. 27370-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2010
  11. Published

    Ligand- and subunit-specific conformational changes in the ligand-binding domain and the TM2-TM3 linker of {alpha}1 {beta}2 {gamma}2 GABAA receptors

    Wang, Q., Pless, Stephan & Lynch, J. W., 17 Dec 2010, In: The Journal of Biological Chemistry. 285, 51, p. 40373-86 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 2011
  13. Published

    Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels

    Pless, Stephan, Galpin, J. D., Frankel, A. & Ahern, C. A., 2011, In: Nature Communications. 2, p. 351

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists

    Pless, Stephan, Hanek, A. P., Price, K. L., Lynch, J. W., Lester, H. A., Dougherty, D. A. & Lummis, S. C. R., Apr 2011, In: Molecular Pharmacology. 79, 4, p. 742-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor potential vanilloid subtype 1 channels in vitro

    Rivera-Acevedo, R. E., Pless, Stephan, Ahern, C. A. & Schwarz, S. K. W., Jun 2011, In: Anesthesiology. 114, 6, p. 1425-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Contributions of counter-charge in a potassium channel voltage-sensor domain

    Pless, Stephan, Galpin, J. D., Niciforovic, A. P. & Ahern, C. A., Sep 2011, In: Nature Chemical Biology. 7, 9, p. 617-23 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Contributions of conserved residues at the gating interface of glycine receptors

    Pless, Stephan, Leung, A. W. Y., Galpin, J. D. & Ahern, C. A., 7 Oct 2011, In: The Journal of Biological Chemistry. 286, 40, p. 35129-36 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 2012
  19. Published

    Extracellular quaternary ammonium blockade of transient receptor potential vanilloid subtype 1 channels expressed in Xenopus laevis oocytes

    Rivera-Acevedo, R. E., Pless, Stephan, Schwarz, S. K. W. & Ahern, C. A., Dec 2012, In: Molecular Pharmacology. 82, 6, p. 1129-35 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Intermediate state trapping of a voltage sensor

    Lacroix, J. J., Pless, Stephan, Maragliano, L., Campos, F. V., Galpin, J. D., Ahern, C. A., Roux, B. & Bezanilla, F., Dec 2012, In: Journal of General Physiology. 140, 6, p. 635-52 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2013
  22. Published

    A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel

    Pless, Stephan, Niciforovic, A. P., Galpin, J. D., Nunez, J., Kurata, H. T. & Ahern, C. A., 2013, In: Nature Communications. 4, p. 1784

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

    Pless, Stephan, Galpin, J. D., Niciforovic, A. P., Kurata, H. T. & Ahern, C. A., 2013, In: eLife. 2, p. e01289

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Unnatural amino acids as probes of ligand-receptor interactions and their conformational consequences

    Pless, Stephan & Ahern, C. A., 2013, In: Annual Review of Pharmacology and Toxicology. 53, p. 211-29 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes

    Rivera-Acevedo, R. E., Pless, Stephan, Schwarz, S. K. W. & Ahern, C. A., 1 Jan 2013, In: Channels (Austin). 7, 1, p. 47-50 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2014
  27. Published

    Caught in the act: multiple binding sites for memantine

    Pless, Stephan, 2014, In: Structure. 22, 10, p. 1373-4 2 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  28. Published

    Principles of agonist recognition in Cys-loop receptors

    Lynagh, T. P. & Pless, Stephan, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p., 160.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains

    Pless, Stephan, Elstone, F. D., Niciforovic, A. P., Galpin, J. D., Yang, R., Kurata, H. T. & Ahern, C. A., May 2014, In: Journal of General Physiology. 143, 5, p. 645-56 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2015
  31. Published

    A conserved residue cluster that governs kinetics of ATP-dependent gating of Kir6.2 potassium channels

    Zhang, R. S., Wright, J., Pless, Stephan, Nunez, J., Kim, R. Y., Li, J. B. W., Yang, R., Ahern, C. A. & Kurata, H. T., 2015, In: The Journal of Biological Chemistry. 290, 25, p. 15450 –15461 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Atomic basis for therapeutic activation of neuronal potassium channels

    Kim, R. Y., Yau, M. C., Galpin, J. D., Seebohm, G., Ahern, C. A., Pless, Stephan & Kurata, H. T., 2015, In: Nature Communications. 6, p. 1-11 11 p., 8116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Introduction: Applying Chemical Biology to Ion Channels

    Pless, Stephan & Ahern, C. A., 2015, Applying Chemical Biology to Ion Channels. Vol. 869. p. 1-4 4 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  34. Published

    Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology

    Pless, Stephan, Kim, R. Y., Ahern, C. A. & Kurata, H. T., 30 Jan 2015, In: The Journal of Physiology. 593, 12, p. 2627–2634 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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