Stephan Pless
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
A Semi-Synthetic Approach to Engineer Ligand- and Voltage-Gated Ion Channels in Live Cells
Khoo, K. K., Galleano, I. & Pless, Stephan, 2019, p. 274A-274A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels
Kim, R. Y., Pless, Stephan & Kurata, H. T., 23 Oct 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 45, p. E9702–E9711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atomic basis for therapeutic activation of neuronal potassium channels
Kim, R. Y., Yau, M. C., Galpin, J. D., Seebohm, G., Ahern, C. A., Pless, Stephan & Kurata, H. T., 2015, In: Nature Communications. 6, p. 1-11 11 p., 8116.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the human sodium leak channel NALCN
Kschonsak, M., Chua, H. C., Noland, C. L., wbv551, wbv551, Clairfeuille, T., Bahlke, O. Ø., Ameen, A. O., Li, Z. R., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2020, In: Nature. 587, p. 313-318Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural architecture of the human NALCN channelosome
Kschonsak, M., Chua, H. C., wbv551, wbv551, Chakouri, N., Noland, C. L., Schott, K., Chang, T., Tam, C., Patel, N., Arthur, C. P., Leitner, A., Ben-Johny, M., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature. 603, p. 180–186Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intermediate state trapping of a voltage sensor
Lacroix, J. J., Pless, Stephan, Maragliano, L., Campos, F. V., Galpin, J. D., Ahern, C. A., Roux, B. & Bezanilla, F., Dec 2012, In: Journal of General Physiology. 140, 6, p. 635-52 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitor-Induced Conformational Changes in ASIC1A
Lund, Camilla, Borg, C. B., Lynagh, T. & Pless, Stephan, 2 Feb 2018, p. 130A-130A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes
Lynagh, T., Mikhaleva, Y., Colding, J. M., Glover, J. C. & Pless, Stephan, 14 Aug 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 33, p. 8430-8435Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen
Lynagh, T., Romero-Rojo, J. L., Lund, Camilla & Pless, Stephan, 12 Oct 2017, In: Journal of Medicinal Chemistry. 60, 19, p. 8192-8200 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A selectivity filter at the intracellular end of the acid-sensing ion channel pore
Lynagh, T., Flood, E., Boiteux, C., Wulf, M., Komnatnyy, V. V., Colding, J. M., Allen, T. W. & Pless, Stephan, 12 May 2017, In: eLife. 6, 21 p., 24630.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction
Lynagh, T., Kiontke, S., Meyhoff-Madsen, M., Gless, B. H., Johannesen, J., Kattelmann, S., Christiansen, A., Dufva, M., Laustsen, A. H., Devkota, K., Olsen, Christian Adam, Kuemmel, D., Pless, Stephan & Lohse, B., 2020, In: Journal of Medicinal Chemistry. 63, 22, p. 13709-13718 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unique contributions of an arginine side chain to ligand recognition in a glutamate-gated chloride channel
Lynagh, T., Komnatnyy, V. V. & Pless, Stephan, 17 Jan 2017, In: The Journal of Biological Chemistry. 292, p. 3940-3946Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of ion selectivity in ASIC1a- and ASIC2a-containing acid-sensing ion channels
Lynagh, T., Flood, E., Boiteux, C., Sheikh, Zeshan Pervez, Allen, T. W. & Pless, Stephan, 3 Feb 2020, In: The Journal of general physiology. 152, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Principles of agonist recognition in Cys-loop receptors
Lynagh, T. P. & Pless, Stephan, 2014, In: Frontiers in Physiology. 5, p. 1-12 12 p., 160.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATP signaling in pancreatic cancer: the P2X7 receptor
Magni, Lara, Bouazzi, R., Christensen, Nynne, Tozzi, M., Poulsen, M., Johansen, J., Pless, Stephan & Novak, Ivana, 2022, In: Acta Physiologica. 236, S725, p. 661-661Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer
Magni, Lara, Yu, Haoran, Christensen, Nynne, Poulsen, Mette Homann, Frueh, A., Deshar, Ganga, Johansen, A. Z., Johansen, Julia Sidenius, Pless, Stephan, Jørgensen, Niklas Rye & Novak, Ivana, 2024, In: Cancer Cell International. 24, 1, 16 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel
Noland, C. L., Chua, H. C., Kschonsak, M., Heusser, Stephanie, Braun, N., Chang, T., Tam, C., Tang, J., Arthur, C. P., Ciferri, C., Pless, Stephan & Payandeh, J., 2022, In: Nature Communications. 13, 1, 10 p., 1416.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The suitability of high throughput automated patch clamp for physiological applications
Obergrussberger, A., Rinke-Weiß, I., Goetze, T. A., Rapedius, M., Brinkwirth, N., Becker, N., Rotordam, M. G., Hutchison, L., Madau, P., Pau, D., Dalrymple, D., Braun, N., Friis, S., Pless, Stephan & Fertig, N., 2022, In: Journal of Physiology. 600, 2, p. 277-297Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction: Applying Chemical Biology to Ion Channels
Pless, Stephan & Ahern, C. A., 2015, Applying Chemical Biology to Ion Channels. Vol. 869. p. 1-4 4 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
A tale of ligands big and small: An update on how pentameric ligand-gated ion channels interact with agonists and proteins
Pless, Stephan & Sivilotti, L. G., 1 Apr 2018, In: Current Opinion in Physiology. 2, p. 19-26 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels
Pless, Stephan, Galpin, J. D., Niciforovic, A. P., Kurata, H. T. & Ahern, C. A., 2013, In: eLife. 2, p. e01289Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology
Pless, Stephan, Kim, R. Y., Ahern, C. A. & Kurata, H. T., 30 Jan 2015, In: The Journal of Physiology. 593, 12, p. 2627–2634 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel
Pless, Stephan, Niciforovic, A. P., Galpin, J. D., Nunez, J., Kurata, H. T. & Ahern, C. A., 2013, In: Nature Communications. 4, p. 1784Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contributions of conserved residues at the gating interface of glycine receptors
Pless, Stephan, Leung, A. W. Y., Galpin, J. D. & Ahern, C. A., 7 Oct 2011, In: The Journal of Biological Chemistry. 286, 40, p. 35129-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain
Pless, Stephan & Lynch, J. W., 5 Jun 2009, In: The Journal of Biological Chemistry. 284, 23, p. 15847-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 93715174
Most downloads
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212
downloads
Unique contributions of an arginine side chain to ligand recognition in a glutamate-gated chloride channel
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
205
downloads
High-Sensitivity Fluorometry to Resolve Ion Channel Conformational Dynamics
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
159
downloads
A selectivity filter at the intracellular end of the acid-sensing ion channel pore
Research output: Contribution to journal › Journal article › Research › peer-review
Published