Stephanie Heusser
Assistant Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
Acid-sensing ion channels as potential therapeutic targets
Heusser, Stephanie & Pless, Stephan, 2021, In: Trends in Pharmacological Sciences. 42, 12, p. 1035-1050Research output: Contribution to journal › Review › Research › peer-review
- Published
Allosteric Gating Determinants in the Transmembrane Domain of Pentameric Ligand-Gated Ion Channels
Howard, R. J., Zhuang, Y., Heusser, Stephanie, Bergh, C. C., Rovsnik, U., Orellana, L. & Lindahl, E., 2020, p. 584A-584A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity
Heusser, Stephanie, Lycksell, M., Wang, X., McComas, S. E., Howard, R. J. & Lindahl, E., 1 Oct 2018, (E-pub ahead of print) In: Proceedings of the National Academy of Sciences of the United States of America. 115, 42, p. 10672-10677Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation
Heusser, Stephanie, Sheikh, Zeshan Pervez, Borg, C. B., Galleano, I. & Pless, Stephan, 2021, p. 337A-337A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Conformational Landscapes of Ligand-Gated Ion Channel GLIC from Markov State Modeling
Bergh, C., Heusser, Stephanie, Howard, R. J. & Lindahl, E. R., 2021, p. 58A-58A.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition
Heusser, Stephanie, Borg, C. B., Colding, J. M. & Pless, Stephan, 2022, In: eLife. 11, 20 p., e73384.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions
Holm, Caroline Marcher, Topaktas, Asli Bahar, Dannesboe, Johs, Pless, Stephan & Heusser, Stephanie, 2024, (E-pub ahead of print) In: Biophysical Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel
Heusser, Stephanie, Yoluk, Ö., Klement, G., Riederer, E. A., Lindahl, E. & Howard, R. J., Jul 2016, In: Journal of Neurochemistry. 138, 2, p. 243-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels
Heusser, Stephanie, Howard, R. J., Borghese, C. M., Cullins, M. A., Broemstrup, T., Lee, U. S., Lindahl, E., Carlsson, J. & Harris, R. A., Nov 2013, In: Molecular Pharmacology. 84, 5, p. 670-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel
Bergh, C., Heusser, Stephanie, Howard, R. & Lindahl, E., 2021, In: eLife. 10, 23 p., 68369.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 203075805
Most downloads
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21
downloads
Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels
Research output: Contribution to journal › Journal article › Research › peer-review
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14
downloads
Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
11
downloads
Characterizing Conformational Changes of ASIC1a During Gating and Peptide Modulation
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Published