Ole Thastrup
Emeritus
Administration and Operations
Jagtvej 160
2100 København Ø
- 1991
The thapsigargin-sensitive intracellular Ca2+ pool is more important in plasma membrane Ca2+ entry than the IP3-sensitive intracellular Ca2+ pool in neuronal cell lines
Takemura, H., Ohshika, H., Yokosawa, N., Oguma, K. & Thastrup, Ole, 1991, In: Biochemical and Biophysical Research Communications. 180, 3, p. 1518-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
Calcium efflux across the plasma membrane of rat parotid acinar cells is unaffected by receptor activation or by the microsomal calcium ATPase inhibitor, thapsigargin
Takemura, H., Thastrup, Ole & Putney, J. W., 1990, In: Cell Calcium. 11, 1, p. 11-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of MeCh, thapsigargin, and La3+ on plasmalemmal and intracellular Ca2+ transport in lacrimal acinar cells
Kwan, C. Y., Takemura, H., Obie, J. F., Thastrup, Ole & Putney, J. W., 1990, In: American Journal of Physiology (Consolidated). 258, 6 Pt 1, p. C1006-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Ca2(+)-ATPases in regulation of cellular Ca2+ signalling, as studied with the selective microsomal Ca2(+)-ATPase inhibitor, thapsigargin
Thastrup, Ole, 1990, In: Agents and Actions. 29, 1-2, p. 8-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase
Thastrup, Ole, Cullen, P. J., Drøbak, B. K., Hanley, M. R. & Dawson, A. P., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2466-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells
Law, G. J., Pachter, J. A., Thastrup, Ole, Hanley, M. R. & Dannies, P. S., 1990, In: Biochemical Journal. 267, 2, p. 359-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase
Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & Thastrup, Ole, 1990, In: F E B S Letters. 260, 1, p. 73-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist
Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, Ole & Schwartz, Thue W., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane
Takemura, H., Hughes, A. R., Thastrup, Ole & Putney, J. W., 1989, In: Journal of Biological Chemistry. 264, 21, p. 12266-71 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin
Foder, B., Scharff, O. & Thastrup, Ole, 1989, In: Cell Calcium. 10, 7, p. 477-90 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
How do inositol phosphates regulate calcium signaling?
Putney, J. W., Takemura, H., Hughes, A. R., Horstman, D. A. & Thastrup, Ole, 1989, In: F A S E B Journal. 3, 8, p. 1899-905 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Internal Ca2+ mobilization and secretion in bovine adrenal chromaffin cells
Cheek, T. R. & Thastrup, Ole, 1989, In: Cell Calcium. 10, 4, p. 213-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Thapsigargin, a new calcium-dependent epithelial anion secretagogue
Brayden, D. J., Hanley, M. R., Thastrup, Ole & Cuthbert, A. W., 1989, In: British Journal of Pharmacology. 98, 3, p. 809-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1988
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells
Jackson, T. R., Patterson, S. I., Thastrup, Ole & Hanley, M. R., 1988, In: Biochemical Journal. 253, 1, p. 81-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS
Scharff, O., Foder, B., Thastrup, Ole, Hofmann, B., Møller, J., Ryder, L. P., Jacobsen, K. D., Langhoff, E., Dickmeiss, E. & Christensen, Søren Brøgger, 1988, In: BBA General Subjects. 972, 3, p. 257-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of thapsigargin in isolated rat thoracic aorta
Mikkelsen, E. O., Thastrup, Ole & Christensen, Søren Brøgger, 1988, In: Pharmacology & Toxicology. 62, 1, p. 7-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Molecular mechanisms of phospholipid signaling pathways in mammalian nerve cells
Hanley, M. R., Jackson, T. R., Cheung, W. T., Dreher, M., Gatti, A., Hawkins, P., Patterson, S. I., Vallejo, M., Dawson, A. P. & Thastrup, Ole, 1988, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 53, Pt 1, p. 435-45 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neural function: metabolism and actions of inositol metabolites in mammalian brain
Hanley, M. R., Jackson, T. R., Vallejo, M., Patterson, S. I., Thastrup, Ole, Lightman, S., Rogers, J., Henderson, G. & Pini, A., 1988, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 320, 1199, p. 381-98 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
Comparison of the action of calcium antagonists on basophil histamine release
Bindslev Jensen, C., Clementsen, P., Stahl Skov, P., Svendsen, U. G., Thastrup, Ole & Norn, S., 1987, In: Allergy: European Journal of Allergy and Clinical Immunology. 42, 6, p. 441-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complexity of the influence of gangliosides on histamine release from human basophils and rat mast cells
Jensen, C., Svendsen, U. G., Thastrup, Ole, Stahl Skov, P., Leon, A. & Norn, S., 1987, In: Agents and Actions. 21, 1-2, p. 79-82 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of nimodipine, verapamil and lanthanum on histamine release from human basophils: effect of pretreatment with sialidase
Jensen, C. B., Thastrup, Ole, Norn, S. & Skov, P. S., 1987, In: Pharmacology & Toxicology. 60, 3, p. 214-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of basophil histamine release by gangliosides. Further studies on the significance of cell membrane sialic acid in the histamine release process
Jensen, C., Norn, S., Thastrup, Ole, Dahl, B. T. & Skov, P. S., 1987, In: Allergy: European Journal of Allergy and Clinical Immunology. 42, 1, p. 51-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Membrane sialic acid influences basophil histamine release by interfering with calcium dependence
Jensen, C., Norn, S., Skov, P. S., Dahl, B. T., Thastrup, Ole, Leon, A. & Svendsen, U. G., 1987, In: Agents and Actions. 20, 3-4, p. 161-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The calcium mobilizing tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion
Thastrup, Ole, Foder, B. & Scharff, O., 1987, In: Biochemical and Biophysical Research Communications. 142, 3, p. 654-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations
Thastrup, Ole, Linnebjerg, H., Bjerrum, P. J., Knudsen, J. B. & Christensen, Søren Brøgger, 1987, In: BBA General Subjects. 927, 1, p. 65-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 343169660
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Short-term spheroid culture of primary colorectal cancer cells as an in vitro model for personalizing cancer medicine
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Characterization of genetic intratumor heterogeneity in colorectal cancer and matching patient-derived spheroid cultures
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