Trine Meldgaard Lund

Trine Meldgaard Lund

Associate Professor

ORCID: 0000-0001-8598-2880

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  1. Published

    Excitatory amino acid receptors: multiplicity and structural requirements for activation and blockade

    Krogsgaard-Larsen, Povl, Lund, Trine Meldgaard, Jørgensen, Flemming Steen & Brehn, L., 1991, Excitatory amino acids and synaptic function. Wheal, H. & Thomson, A. (eds.). London: Academic Press, p. 1-17 17 p. (Excitatory Amino Acids and Synaptic Transmission, Academic Press, London).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  2. Published

    Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

    Krogsgaard-Larsen, Povl, Ebert, B., Lund, Trine Meldgaard, Bräuner, Hans, Sloøk, F. A., Johansen, Tommy Nørskov, Brehm, L. & Madsen, Ulf, 10 Sep 1996, In: European Journal of Medicinal Chemistry. 31, 7-8, p. 515-537 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    AMPA receptor agonists, design, synthesis and molecular pharmacology

    Lund, Trine Meldgaard, Christensen, I. T., Madsen, Ulf, Ebert, B., Brehm, L. & Krogsgaard-Larsen, Povl, 1990, In: Neurochemistry International. 16 suppl 1, 51, p. 51 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  4. Published

    Det glutamaterge system: neurokemisk patologi af Alzheimers syge og medicinalkemiske studier af glutaminsyrereceptorerne

    Lund, Trine Meldgaard, 1992, 138 p. Kbh : Danmarks Farmaceutiske Højskole. Institut for Organisk Kemi.

    Research output: Other contribution › Research

  5. Published

    Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons

    Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity

    Lund, Trine Meldgaard, Ploug, K. B., Iversen, A., Jensen, Anders A. & Jansen-Olesen, I., 2015, In: Journal of Neurochemistry. 132, 5, p. 520-531 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Stofskiftesygedomme - Fra gen til terapi

    Lund, Trine Meldgaard, Christensen, E., Schousboe, A. & Meldgaard Lund, A., 1 Jan 2001, In: Lægemiddelforskning. p. 12-13 40 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In: Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    GABA synthesis from ß-hydroxybutyrate and glucose is differentially affected by neuronal activity in cultured GABAergic neurons

    Lund, Trine Meldgaard, Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s2, p. 95

    Research output: Contribution to journal › Conference abstract in journal › Research

  10. Published

    ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity

    Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116

    Research output: Contribution to journal › Conference abstract in journal › Research

  11. Published

    On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1

    Lund, Trine Meldgaard, Christensen, E., Kristensen, Anders Skov, Schousboe, Arne & Lund, Allan Meldgaard, 2004, In: Journal of Neuroscience Research. 77, 1, p. 143-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate

    Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291

    Research output: Contribution to journal › Conference abstract in journal › Research

  13. Published

    Conformational and pharmacological characterization of 4-AHCP, a bicyclic homologue of the excitatory amino acid receptor agonist AMPA

    Lund, Trine Meldgaard, Madsen, Ulf, Ebert, B., Jørgensen, Flemming Steen & Krogsgaard-Larsen, Povl, 1991, In: Med. Chem. Res. 1, p. 136-141 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming Recommendations

    Lyauk, Y. K., Jonker, D. M. & Lund, Trine Meldgaard, 2019, In: Clinical and Translational Science. 12, 5, p. 481-489

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

    Lyauk, Y. K., Lund, Trine Meldgaard, Hooker, A. C., Karlsson, M. O. & Jonker, D. M., 2020, In: The AAPS Journal. 22, 5, 13 p., 98.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Item Response Theory Modeling of the International Prostate Symptom Score in Patients with Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

    Lyauk, Y. K., Jonker, D. M., Lund, Trine Meldgaard, Hooker, A. C. & Karlsson, M. O., 2020, In: The AAPS Journal. 22, 5, 15 p., 115.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

    Lyauk, Y. K., Jonker, D. M., Hooker, A., Lund, Trine Meldgaard & Karlsson, M. O., 2021, In: The AAPS journal. 23, 2, 14 p., 33.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells

    Maar, T. E., Lund, Trine Meldgaard, Gegelashvili, G., Hartmann-Petersen, Rasmus, Moran, M. J., Pasantes-Morales, H., Berezin, V., Bock, E. & Schousboe, Arne, 1998, In: Amino Acids. 15, 1, p. 77-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Design, synthesis and pharmacology of model compounds for indirect elucidation of the topography of AMPA receptor sites

    Madsen, Ulf, Frølund, Bente, Lund, Trine Meldgaard, Ebert, B. & Krogsgaard-Larsen, Povl, 1993, In: European Journal of Medicinal Chemistry. 28, p. 791–800

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Evaluation of Multi-Frequency Bioelectrical Impedance Analysis against Dual-Energy X-ray Absorptiometry for Estimation of Low Muscle Mass in Older Hospitalized Patients

    Nielsen, R. L., Andersen, A. L., Kallemose, T., Damgaard, Morten, Bornæs, O., Juul-Larsen, H. G., Strejby Christensen, L. W., Jawad, B. N., Andersen, Ove, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard & Houlind, Morten Baltzer, 2024, In: Journal of Clinical Medicine. 13, 1, 15 p., 196.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Appetite stimulation with cannabis-based medicine and methods for assessment of glomerular filtration in older patients with medical illness: A study protocol

    Nielsen, R. L., Bornæs, O., Storgaard, I. K., Kallemose, T., Jørgensen, L. M., Jawad, B. N., Altintas, I., Juul-larsen, H. G., Tavenier, J., Durhuus, J. A., Bengaard, A. K. P., Holst, J. J., Kolko, M., Sonne, D. P., Breindahl, T., Damgaard, M., Porrini, E., Hornum, M., Andersen, O., Pedersen, M. M. & 6 others, Rasmussen, H. H., Munk, T., Lund, Trine Meldgaard, Jensen, A. P. S. L., Andersen, A. L. & Houlind, Morten Baltzer, 2023, In: Basic & Clinical Pharmacology & Toxicology. 133, 3, p. 237-253 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

    Nøhr-Nielsen, A., Lange, Theis, Forman, Julie Lyng, Papathanasiou, T., Foster, D. J. R., Upton, R. N., Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2020, In: The AAPS Journal. 22, 2, 32.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

    Nøhr-Nielsen, A., De Bruin, M. L., Thomsen, M., Pipper, C. B., Lange, Theis, Bjerrum, Ole Jannik & Lund, Trine Meldgaard, 2019, In: British Journal of Clinical Pharmacology. 85, 8, p. 1829-1840 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Pharmacodynamic modelling reveals synergistic interaction between docetaxel and SCO-101 in a docetaxel-resistant triple negative breast cancer cell line

    Nøhr-Nielsen, A., Bagger, Sofie Morsing, Brünner, N., Stenvang, Jan & Lund, Trine Meldgaard, 2020, In: European Journal of Pharmaceutical Sciences. 148, 10 p., 105315.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach

    Papathanasiou, T., Juul, R. V., Gabel-Jensen, C., Kreilgaard, M., Heegaard, Anne-Marie & Lund, Trine Meldgaard, 1 Nov 2017, In: AAPS Journal. 19, 6, p. 1804–1813 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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