Trine Meldgaard Lund

Trine Meldgaard Lund

Associate Professor

ORCID: 0000-0001-8598-2880

Publication year:
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  1. 1990
  2. Published

    AMPA receptor agonists, design, synthesis and molecular pharmacology

    Lund, Trine Meldgaard, Christensen, I. T., Madsen, Ulf, Ebert, B., Brehm, L. & Krogsgaard-Larsen, Povl, 1990, In: Neurochemistry International. 16 suppl 1, 51, p. 51 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  3. 1991
  4. Published

    Conformational and pharmacological characterization of 4-AHCP, a bicyclic homologue of the excitatory amino acid receptor agonist AMPA

    Lund, Trine Meldgaard, Madsen, Ulf, Ebert, B., Jørgensen, Flemming Steen & Krogsgaard-Larsen, Povl, 1991, In: Med. Chem. Res. 1, p. 136-141 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Excitatory amino acid receptors: multiplicity and structural requirements for activation and blockade

    Krogsgaard-Larsen, Povl, Lund, Trine Meldgaard, Jørgensen, Flemming Steen & Brehn, L., 1991, Excitatory amino acids and synaptic function. Wheal, H. & Thomson, A. (eds.). London: Academic Press, p. 1-17 17 p. (Excitatory Amino Acids and Synaptic Transmission, Academic Press, London).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  6. 1992
  7. Published

    AMPA receptor agonists: structural, conformational and stereochemical aspects

    Hansen, J., Jørgensen, Flemming Steen, Lund, Trine Meldgaard, Nielsen, Birgitte, Reinhardt, A., Breum, I., Brehm, L. & Krogsgaard-Larsen, Povl, 1992, Excitatory Amino Acid Receptors. Krogsgaard-Larsen, P. & Hansen, J. J. (eds.). Ellis Horwood: Chichester, 30 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  8. Published

    Det glutamaterge system: neurokemisk patologi af Alzheimers syge og medicinalkemiske studier af glutaminsyrereceptorerne

    Lund, Trine Meldgaard, 1992, 138 p. Kbh : Danmarks Farmaceutiske Højskole. Institut for Organisk Kemi.

    Research output: Other contribution › Research

  9. Published

    Subtype-selective excitatory amino acid receptor agonists and antagonists derived from ibotenic acid

    Ebert, B., Lund, Trine Meldgaard, Madsen, Ulf, Brehm, L. & Krogsgaard-Larsen, Povl, 1992, New leads and targets in drug research: Alfred Benzon Symposium 33. Krogsgaard-Larsen, P., Christensen, S. B. & Kofod, H. (eds.). Copenhagen, p. 340-351 11 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  10. Published

    Molecular pharmacology of cortical and spinal AMPA receptors

    Ebert, B., Madsen, Ulf, Lund, Trine Meldgaard, Holm, T. & Krogsgaard-Larsen, Povl, 1 Jan 1992, In: Molecular Neuropharmacology. 2, 1, p. 47-49 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Hydroxylated analogues of 5-aminovaleric acid as 4-aminobutyric acidB receptor antagonists: stereostructure-activity relationships

    Kristiansen, Uffe, bjl587, bjl587, Herdeis, C., Lund, Trine Meldgaard, Nielsen, Birgitte, Hansen, J. J., Falch, E., Hjeds, H. & Krogsgaard-Larsen, Povl, Mar 1992, In: Journal of Neurochemistry. 58, 3, p. 1150-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. 1993
  13. Published

    Design, synthesis and pharmacology of model compounds for indirect elucidation of the topography of AMPA receptor sites

    Madsen, Ulf, Frølund, Bente, Lund, Trine Meldgaard, Ebert, B. & Krogsgaard-Larsen, Povl, 1993, In: European Journal of Medicinal Chemistry. 28, p. 791–800

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 1994
  15. Published

    Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA

    Ebert, B., Madsen, Ulf, Lund, Trine Meldgaard, Lenz, S. M. & Krogsgaard-Larsen, Povl, Jun 1994, In: Neurochemistry International. 24, 6, p. 507-15 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 1996
  17. Published

    Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

    Krogsgaard-Larsen, Povl, Ebert, B., Lund, Trine Meldgaard, Bräuner, Hans, Sloøk, F. A., Johansen, Tommy Nørskov, Brehm, L. & Madsen, Ulf, 10 Sep 1996, In: European Journal of Medicinal Chemistry. 31, 7-8, p. 515-537 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. 1998
  19. Published

    Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells

    Maar, T. E., Lund, Trine Meldgaard, Gegelashvili, G., Hartmann-Petersen, Rasmus, Moran, M. J., Pasantes-Morales, H., Berezin, V., Bock, E. & Schousboe, Arne, 1998, In: Amino Acids. 15, 1, p. 77-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 1999
  21. Published

    Differential localization of voltage-gated calcium channels in neurites and somata of cultured neocortical neurons.

    Timmermann, D., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 1999, In: Journal of Neurochemistry. 73, Suppl, p. 127 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. 2001
  23. Published

    Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons

    Timmermann, D. B., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 2001, In: International Journal of Developmental Neuroscience. 19, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

    Jensen, J. B., Lund, Trine Meldgaard, Timmermann, D. B., Schousboe, Arne & Pickering, Darryl S, 2001, In: Journal of Neuroscience Research. 65, 3, p. 267-277 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Stofskiftesygedomme - Fra gen til terapi

    Lund, Trine Meldgaard, Christensen, E., Schousboe, A. & Meldgaard Lund, A., 1 Jan 2001, In: Lægemiddelforskning. p. 12-13 40 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2004
  27. Published

    On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1

    Lund, Trine Meldgaard, Christensen, E., Kristensen, Anders Skov, Schousboe, Arne & Lund, Allan Meldgaard, 2004, In: Journal of Neuroscience Research. 77, 1, p. 143-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2005
  29. Published

    Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter

    Brown, A. M., Sickmann, H. M., Fosgerau, K., Lund, Trine Meldgaard, Schousboe, Arne, Waagepetersen, Helle S. & Ransom, B. R., 2005, In: Journal of Neuroscience Research. 79, 1-2, p. 74-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Occurence of N-acylethanolamines and their precursors in neuronal rafts

    Petersen, G., Lund, Trine Meldgaard & Hansen, Harald S., 2005, In: Chemistry and Physics of Lipids. 136, 2, p. 106-107 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  31. Published

    Kroppens egne cannabinoider påvirker immunsystemet

    Degn, M., Hansen, Harald S., Lund, Trine Meldgaard & Petersen, G., 1 Jan 2005, In: Lægemiddelforskning. p. 8 9 p., 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2007
  33. Published

    Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

    Degn, M., Lambertsen, K. L., Petersen, G., Meldgaard, M., Artmann, A., Clausen, B. H., Hansen, S. H., Finsen, B., Hansen, Harald S. & Lund, Trine Meldgaard, 2007, In: Journal of Neurochemistry. 103, 5, p. 1907-1916

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity

    Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. 2009
  36. Published

    Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate

    Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291

    Research output: Contribution to journal › Conference abstract in journal › Research

  37. Published

    Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons

    Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    GABA synthesis from ß-hydroxybutyrate and glucose is differentially affected by neuronal activity in cultured GABAergic neurons

    Lund, Trine Meldgaard, Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s2, p. 95

    Research output: Contribution to journal › Conference abstract in journal › Research

  39. Published

    Impact of the malate-aspartate shuttle in glutamate neurotransmission

    Waagepetersen, Helle S., Bak, Lasse Kristoffer, Lund, Trine Meldgaard, Walls, A. B., Sonnewald, U. & Schousboe, Arne, 2009, In: Journal of Neurochemistry. s1, p. 9

    Research output: Contribution to journal › Conference abstract in journal › Research

  40. 2011
  41. Published

    Development of quantitative pharmacology-pharmacometrics in Denmark

    Honoré, P. G. H., Bjerrum, Ole Jannik, Lund, Trine Meldgaard, Angelo, H., Ingwersen, S. H., Thygesen, P., Kristensen, K. & Larsen, F., 2011.

    Research output: Contribution to conference › Poster › Research

  42. Published

    ß-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

    Lund, Trine Meldgaard, Obel, L. F., Risa, Ø. & Sonnewald, U., 1 Aug 2011, In: Neurochemistry International. 59, 2, p. 309-18 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. 2012
  44. Published

    KATP channel openers in the trigeminalvascular system

    Ploug, K. B., Amrutkar, D. V., Baun, M., Ramachandran, R., Iversen, A., Lund, Trine Meldgaard, Gupta, S., Hay-Schmidt, A., Olesen, J. & Jansen-Olesen, I., 2012, In: Cephalagia. 32, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2013
  46. Published

    Modelling analgesia-concentration relationships for morphine to evaluate experimental pain models

    Sverrisdóttir, E., Foster, D., Upton, R., Olesen, A. E., Lund, Trine Meldgaard, Christrup, Lona Louring & Kreilgaard, M., 2013, Population Approach Group in Europe.

    Research output: Other contribution › Research

  47. Published

    Modelling analgesia-concentration relationships for morphine to evaluate experimental pain models

    Sverrisdóttir, E., Foster, D., Upton, R., Olesen, A. E., Lund, Trine Meldgaard, Christrup, Lona Louring & Kreilgaard, M., Jun 2013.

    Research output: Contribution to conference › Poster › Research

  48. Published

    How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management

    Juul, R. V., Rasmussen, S., Kreilgaard, M., Simonsson, U., Christrup, Lona Louring & Lund, Trine Meldgaard, 5 Aug 2013.

    Research output: Contribution to conference › Poster › Research

  49. 2014
  50. Published

    How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management

    Juul, R. V., Rasmussen, S., Kreilgaard, M., simonsson, U., Christrup, Lona Louring & Lund, Trine Meldgaard, 11 Jul 2014.

    Research output: Contribution to conference › Poster › Research

  51. 2015
  52. Published

    Repeated Time-to-event Analysis of Consecutive Analgesic Events in Postoperative Pain

    Juul, R. V., Rasmussen, S., Kreilgaard, M., Christrup, Lona Louring, Simonsson, U. S. H. & Lund, Trine Meldgaard, 2015, In: Anesthesiology. 123, 12, p. 1411-1419 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity

    Lund, Trine Meldgaard, Ploug, K. B., Iversen, A., Jensen, Anders A. & Jansen-Olesen, I., 2015, In: Journal of Neurochemistry. 132, 5, p. 520-531 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    COMBINATION OF MORPHINE AND GABAPENTIN LEADS TO SYNERGISTIC EFFECTS IN A RAT MODEL OF POSTOPERATIVE PAIN

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 14 Jan 2015.

    Research output: Contribution to conference › Poster › Research

  55. Published

    Determination of gastric emptying and small intestine transit time in dogs by paracetamol and sulfapyridine absorption modelling using nonlinear mixed-effects pharmacokinetics

    Hadji-Popovski, K., Skyggebjerg, R., Ynddal, L., Lund, Trine Meldgaard & Kristensen, K., 14 Jan 2015.

    Research output: Contribution to conference › Poster › Research

  56. Published

    Determination of gastric emptying in dogs by paracetamol absorption test using nonlinear mixed-effects pharmacokinetics

    Hadji-Popovski, K., Vegge, A., Olsen, J., Lund, Trine Meldgaard & Kristensen, K., 14 Jan 2015.

    Research output: Contribution to conference › Poster › Research

  57. Published

    Modelling concentration-analgesia relationships for morphine to evaluate experimental pain models

    Sverrisdóttir, E., Foster, D. J. R., Upton, R. N., Olesen, A. E., Lund, Trine Meldgaard, Gabel-Jensen, C., Drewes, A. M., Christrup, Lona Louring & Kreilgaard, M., 23 Jan 2015, In: European Journal of Pharmaceutical Sciences. 66, p. 50-58 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Carnitine Levels in Skeletal Muscle, Blood, and Urine in Patients with Primary Carnitine Deficiency During Intermission of L-Carnitine Supplementation

    Rasmussen, J., Thomsen, J. A., Olesen, J. H., Lund, Trine Meldgaard, Mohr, M., Clementsen, J., Nielsen, Olav Wendelboe & Lund, A. M., 10 Feb 2015, JIMD Reports. Zschocke, J., Baumgartner, M., Morava, E., Patterson, M., Rahman, S. & Peters, V. (eds.). Berlin: Springer, Vol. 20. p. 103-111 9 p. (JIMD Reports).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  59. Published

    A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain

    Sverrisdóttir, E., Lund, Trine Meldgaard, Olesen, A. E., Drewes, A. M., Christrup, Lona Louring & Kreilgaard, M., 7 Apr 2015, In: European Journal of Pharmaceutical Sciences. 74, p. 45–62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Exploring the relationship between analgesic event rate and pain intensity in kidney stone surgery: A Repeated Time to Event Pilot Study

    Juul, R. V., Pedersen, K. V., Christrup, Lona Louring, Olesen, A. E., Drewes, A., Osther, P. J. S. & Lund, Trine Meldgaard, Jun 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  61. Published

    Response surface analysis of synergistic interactions of morphine and gabapentin in a rat model of postoperative pain.

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 19 Oct 2015.

    Research output: Contribution to conference › Poster › Research

  62. 2016
  63. Published

    A pharmacokinetic-pharmacodynamic model of morphine exposure and subsequent morphine consumption in postoperative pain

    Juul, R. V., Nyberg, J., Lund, Trine Meldgaard, Rasmussen, S., Kreilgaard, M., Christrup, Lona Louring & Simonsson, U. S. H., 2016, In: Pharmaceutical Research. 33, 5, p. 1093–1103 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain

    Papathanasiou, T., Juul, R. V., Heegaard, Anne-Marie, Kreilgaard, M. & Lund, Trine Meldgaard, 2016, In: European Journal of Pharmaceutical Sciences. 82, p. 97–105 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Population pharmacokinetic modelling of morphine, gabapentin and their combination in the rat

    Papathanasiou, T., Juul, R. V., Gabel-Jensen, C., Kreilgaard, M. & Lund, Trine Meldgaard, 2016, In: Pharmaceutical Research. 33, 11, p. 2630–2643 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain

    Knøsgaard, K., Juul, R. V., Olesen, A. E., Pedersen, K. V., Kreilgaard, M., Christrup, Lona Louring, Osther, P. J. S., Drewes, A. M. & Lund, Trine Meldgaard, Jun 2016.

    Research output: Contribution to conference › Poster › Research

  67. Published

    Pharmacokinetic Metamodel of Morphine and Morphine-6-Glucuronide in Neonates and Adults

    Sverrisdóttir, E., Foster, D. J. R., Olesen, A. E., Lund, Trine Meldgaard, Drewes, A. M., Christrup, Lona Louring, Kreilgaard, M. & Upton, R. N., Jun 2016.

    Research output: Contribution to conference › Poster › Research

  68. Published

    A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain

    Juul, R. V., Knøsgaard, K. R., Olesen, A. E., Pedersen, K. V., Kreilgaard, M., Christrup, Lona Louring, Osther, P. J., Drewes, A. M. & Lund, Trine Meldgaard, Jul 2016, In: A A P S Journal. 18, 4, p. 1013-1022 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. 2017
  70. Published

    Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches

    Juul, R. V., Nyberg, J., Kreilgaard, M., Christrup, Lona Louring, Simonsson, U. S. H. & Lund, Trine Meldgaard, Aug 2017, In: Journal of Pharmacokinetics and Pharmacodynamics. 44, 4, p. 325-333 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 1303792