Trond Ulven

Trond Ulven

Professor

Member of:


    1. 2016
    2. Treatment with TUG891, a free fatty acid receptor 4 agonist, restores adipose tissue metabolic dysfunction following chronic sleep fragmentation in mice

      Gozal, D., Qiao, Z., Almendros, I., Zheng, J., Khalyfa, A., Shimpukade, B. & Ulven, Trond, 2016, In: International Journal of Obesity. 40, 7, p. 1143-1149 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor

      Grundmann, M., Tikhonova, I. G., Hudson, B. D., Smith, N. J., Mohr, K., Ulven, Trond, Milligan, G., Kenakin, T. & Kostenis, E., 17 Mar 2016, In: Cell Chemical Biology. 23, 3, p. 392-403 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Controlled generation and use of CO in flow

      Hansen, S. V. F., Wilson, Z. E., Ulven, Trond & Ley, S. V., 2016, In: Reaction Chemistry & Engineering. 1, 3, p. 280-287 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Discovery of a Potent Free Fatty Acid 1 Receptor Agonist with Low Lipophilicity, Low Polar Surface Area and Robust in Vivo Efficacy

      Hansen, S. V. F., Ulven, Elisabeth Rexen, Urban, C., Hudson, B. D., Stocker, C. J., Due-Hansen, M. E., Wargent, E. T., Shimpukade, B., Almeida, R., Ejsing, C. S., Cawthorne, M. A., Kassack, M. U., Milligan, G. & Ulven, Trond, 1 Mar 2016, In: Journal of Medicinal Chemistry. 59, 6, p. 2841-2846 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)

      Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Distinct Phosphorylation Clusters Determine the Signaling Outcome of Free Fatty Acid Receptor 4/G Protein-Coupled Receptor 120

      Prihandoko, R., Alvarez-Curto, E., Hudson, B. D., Butcher, A. J., Ulven, Trond, Miller, A. M., Tobin, A. B. & Milligan, G., 2016, In: Molecular Pharmacology. 89, 5, p. 505-520 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands

      Sergeev, E., Hojgaard Hansen, A., Pandey, S. K., Mackenzie, A. E., Hudson, B. D., Ulven, Trond & Milligan, G., 2016, In: Journal of Biological Chemistry. 291, p. 303-317 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. 2015
    10. Published

      Oxalyl chloride as a practical carbon monoxide source for carbonylation reactions

      Hansen, S. V. F. & Ulven, Trond, 5 Jun 2015, In: Organic Letters. 17, 11, p. 2832-2835 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Characterising pharmacological ligands to study the long chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

      Milligan, G., Alvarez-Curto, E., Watterson, K. R., Ulven, Trond & Hudson, B. D., 2015, In: British Journal of Pharmacology. 172, 13, p. 3254-3265 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MSALL

      Sokol, O., Ulven, Trond, Færgeman, N. J. & Ejsing, C. S., 2015, In: European Journal of Lipid Science and Technology. 117, 6, p. 751-759 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Dietary Fatty Acids and Their Potential for Controlling Metabolic Diseases Through Activation of FFA4/GPR120

      Ulven, Trond & Ulven, Elisabeth Rexen, 17 Jul 2015, In: Annual Review of Nutrition. 35, p. 239-263 25 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. 2014
    15. Concomitant action of structural elements and receptor phosphorylation determines arrestin-3 interaction with the free fatty acid receptor FFA4

      Butcher, A. J., Hudson, B. D., Shimpukade, B., Alvarez-Curto, E., Prihandoko, R., Ulven, Trond, Milligan, G. & Tobin, A. B., 27 Jun 2014, In: Journal of Biological Chemistry. 289, 26, p. 18451-18465 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands

      Hudson, B. D., Ulven, Elisabeth Rexen, Murdoch, H., Jenkins, L., Hansen, A. H., Madsen, O., Ulven, Trond & Milligan, G., Aug 2014, In: Molecular Pharmacology. 86, 2, p. 200-210 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120)

      Hudson, B. D., Shimpukade, B., Milligan, G. & Ulven, Trond, 18 Jul 2014, In: Journal of Biological Chemistry. 289, 29, p. 20345-20358 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Direct N9-arylation of purines with aryl halides

      Larsen, A. F. & Ulven, Trond, 21 May 2014, In: Chemical Communications. 50, 39, p. 4997-4999 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. G-protein-coupled receptors for free fatty acids

      Milligan, G., Ulven, Trond, Murdoch, H. & Hudson, B. D., 2 Jan 2014, In: British Journal of Nutrition. 111, Supplement S1, p. S3-S7

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Phenanthroline-2,9-bistriazoles as selective G-quadruplex ligands

      Nielsen, M. C., Larsen, A. F., Abdikadir, F. H. & Ulven, Trond, 2014, In: European Journal of Medicinal Chemistry. 72, p. 119-126 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Treatment of type 2 diabetes by free Fatty Acid receptor agonists

      Watterson, K. R., Hudson, B. D., Ulven, Trond & Milligan, G., 2014, In: Frontiers in Endocrinology. 5

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. 2013
    23. Published

      Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators

      Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Discovery of TUG-770

      Ulven, Elisabeth Rexen, Hansen, S. V. F., Urban, C., Hudson, B. D., Wargent, E. T., Grundmann, M., Jenkins, L., Zaibi, M., Stocker, C. J., Ullrich, S., Kostenis, E., Kassack, M. U., Milligan, G., Cawthorne, M. A. & Ulven, Trond, 9 May 2013, In: A C S Medicinal Chemistry Letters. 4, 5, p. 441-445 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Discovery of a potent and selective free fatty acid receptor 1 agonist with low lipophilicity and high oral bioavailability

      Ulven, Elisabeth Rexen, Due-Hansen, M. E., Urban, C., Grundmann, M., Schmidt, J., Hansen, S. V. F., Hudson, B. D., Zaibi, M., Markussen, S. B., Hagesaether, E., Milligan, G., Cawthorne, M. A., Kostenis, E., Kassack, M. U. & Ulven, Trond, 14 Feb 2013, In: Journal of Medicinal Chemistry. 56, 3, p. 982-992 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Selective copper catalysed aromatic N-arylation in water

      Engel-Andreasen, J., Shimpukade, B. & Ulven, Trond, 2013, In: Green Chemistry. 15, 2, p. 336-340 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Mucus can change the permeation rank order of drug candidates

      Hagesaether, E., Ulven, Elisabeth Rexen, Due-Hansen, M. E. & Ulven, Trond, 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 276-282 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

      Hudson, B. D., Due-Hansen, M. E., Ulven, Elisabeth Rexen, Hansen, A., Mackenzie, A. E., Murdoch, H., Pandey, S. K., Ward, R. J., Marquez, R., Tikhonova, I. G., Ulven, Trond & Milligan, G., 14 Jun 2013, In: Journal of Biological Chemistry. 288, p. 17296-17312 17 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism

      Hudson, B. D., Shimpukade, B., Mackenzie, A. E., Butcher, A. J., Pediani, J. D., Ulven, Elisabeth Rexen, Heathcote, H., Tobin, A. B., Ulven, Trond & Milligan, G., 2013, In: Molecular Pharmacology. 84, 5, p. 710-725 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 187375453