Uffe Kristiansen

Uffe Kristiansen

Associate Professor


  1. 2002
  2. Published

    Novel class of potent 4-arylalkyl substituted 3-isoxazolol GABAA antagonists: Synthesis, pharmacology, and molecular modeling

    Frølund, Bente, Jørgensen, A. T., Tagmose, L., Stensbøl, T. B., Vestergaard, H. T., Engblom, C., Kristiansen, Uffe, Sanchez, C., Krogsgaard-Larsen, Povl & Liljefors, T., 6 Jun 2002, In: Journal of Medicinal Chemistry. 45, 12, p. 2454-2468 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    GABA(A) receptor ligands and their therapeutic potentials.

    Frølund, Bente, Ebert, B., Kristiansen, Uffe, Liljefors, T. & Krogsgaard-Larsen, Povl, Aug 2002, In: Current Topics in Medicinal Chemistry. 2, 8, p. 817-832 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  4. 2003
  5. Published

    Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists

    Frølund, Bente, Tagmose, L., Jørgensen, A. T., Kristiansen, Uffe, Stensbøl, T. B., Liljefors, T. & Krogsgaard-Larsen, Povl, 2003, In: European Journal of Medicinal Chemistry. 38, p. 447–449

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Design and synthesis of a new series of 4-alkylated 3-isoxazolol GABAA antagonists

    Frølund, Bente, Tagmose, L., Jørgensen, A. T., Kristiansen, Uffe, Stensbøl, T. B., Liljefors, T. & Krogsgaard-Larsen, Povl, 1 Apr 2003, In: European Journal of Medicinal Chemistry. 38, 4, p. 447-449 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2004
  8. Published

    Activation on single heteromeric GABAA receptor Ion channels by full and partial agonists

    Mortensen, M., Kristiansen, Uffe, Ebert, B., Frølund, Bente, Krogsgaard-Larsen, Povl & Smart, T., 2004, In: Journal of Physiology. p. 393–417

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Functional characterisation of the human alpha1 glycine receptor in a fluorescence-based membrane potential assay

    Jensen, Anders A. & Kristiansen, Uffe, 2004, In: Biochemical Pharmacology. 67, 9, p. 1789-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Direct Optical Detection of Singlet Oxygen from a Single Cell

    Zebger, I., Snyder, J. W., Andersen, L. K., Poulsen, L., Gao, Z., Lambert, J. D. C., Kristiansen, Uffe & Ogilby, P. R., Apr 2004, In: Photochemistry and Photobiology. 79, 4, p. 319-322 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Activation of single heteromeric GABAA receptor ion channels by full and partial agonists

    Mortensen, M., Kristiansen, Uffe, Ebert, B., Frølund, Bente, Krogsgaard-Larsen, Povl & Smart, T. G., 1 Jun 2004, In: Journal of Physiology. 557, 2, p. 389-413 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2005
  13. Published

    Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABAA antagonists: Synthesis, pharmacology, and molecular modeling

    Frølund, Bente, Jensen, L. S., Guandalini, L., Canillo, C., Vestergaard, H. T., Kristiansen, Uffe, Nielsen, Birgitte, Stensbøl, T. B., Madsen, C., Krogsgaard-Larsen, Povl & Liljefors, T., 27 Jan 2005, In: Journal of Medicinal Chemistry. 48, 2, p. 427-439 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2006
  15. Published

    Effekt og bivirkninger: GABA fra A til C.

    Frølund, Bente, Madsen, C., Jensen, Anders A., Kristiansen, Uffe & Liljefors, T., 2006, In: Lægemiddelforskning. p. 32-33

    Research output: Contribution to journalJournal articleCommunication

  16. Published

    Hydroxy-1,2,5-oxadiazolyl moiety as bioisoster of the carboxy function.Synthesis, ionization constants and pharmacological characterization of gamma-aminobutyric acid (GABA) related compounds

    Lolli, M. L., Hansen, S. L., Rolando, B., Nielsen, Birgitte, Wellendorph, Petrine, Madsen, K., Larsen, O. M., Kristiansen, Uffe, Fruttero, R., Gasco, A. & Johansen, Tommy Nørskov, 2006, In: J. Med. Chem.. 49, p. 4442-4446 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2007
  18. Published

    5-Substituted imidazole-4-acetic acid analogues: Synthesis, modeling, and pharmacological characterization of a series of novel γ-aminobutyric acidC receptor agonists

    Madsen, C., Jensen, Anders A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, p. 4147-4161

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    5-substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel ¿-aminobutyric acidC receptor agonists

    Madsen, C., Jensen, A. A., Liljefors, T., Kristiansen, Uffe, Nielsen, Birgitte, Hansen, C. P., Larsen, M., Ebert, B., Bang-Andersen, B., Krogsgaard-Larsen, Povl & Frølund, Bente, 2007, In: Journal of Medicinal Chemistry. 50, 17, p. 4147-4161

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Differences in kinetics of structurally related competitive GABAA receptor antagonists

    Vestergaard, H. T., Cannillo, C., Frølund, Bente & Kristiansen, Uffe, 2007, In: Neuropharmacology. 52, 3, p. 873-882

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Probing the pharmacophore of ginkgolides as glycine receptor antagonists

    Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In: Journal of Medicinal Chemistry. 50, 7, p. 1610-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2008
  23. Published

    Effect of acute injections of the ketone bodies in PTZ kindled mice

    Hansen, S. L., Riisberg, M., Nouri-Nejad, A., Skonberg, C., Kristiansen, Uffe & Hansen, Harald S., 2008.

    Research output: Contribution to conferencePosterResearch

  24. Published

    Ligands for the GABA recognition site at the GABAA receptor: Structure-activity studies

    Frølund, Bente, Kristiansen, Uffe, Krogsgaard-Larsen, Povl & Liljefors, T., 2008, Chemistry and molecular aspects of drug design and action. Rekka, E. A. & Kourounakis, P. N. (eds.). Boca Raton, Fl: CRC Press, p. 139-147

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  25. 2009
  26. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: Implications for control of behavioral state

    Kohlmeier, Kristi Anne & Kristiansen, Uffe, 2009, In: Journal of Neuroscience.

    Research output: Contribution to journalConference abstract in journalResearch

  27. Published

    Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus

    Hansen, S. L., Nielsen, A. H., Knudsen, K. E., Artmann, A., Kristiansen, Uffe, Hansen, S. H., Hansen, Harald S. & Petersen, G., 2009, In: Neurochemistry International. 54, 3-4, p. 199-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2010
  29. Published

    Effect of Rhoicissus digitata extracts on acetylcholine-mediated contraction in rat uterus

    Schou, J., Kristiansen, Uffe, Stafford, G. I., van Heerden, F. & Jäger, A., Aug 2010, In: Planta Medica. 76, 12, p. 1217

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    GABAergic actions on cholinergic laterodorsal tegmental neurons: implications for control of behavioral state

    Kohlmeier, Kristi Anne & Kristiansen, Uffe, 15 Dec 2010, In: Neuroscience. 171, 3, p. 812-29 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2011
  32. Published

    Acute but not delayed amphetamine treatment improves behavioral outcome in a rat embolic stroke model

    Rasmussen, Rune Skovgaard, Overgaard, K., Kristiansen, Uffe & Johansen, F. F., Sep 2011, In: Neurological Research. 33, 7, p. 774-782 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Uterine contraction induced by Tanzanian plants used to induce abortion

    Nikolajsen, T., Nielsen, F., Rasch, V., Sørensen, P. H., Ismail, F., Kristiansen, Uffe & Jäger, A. K., 1 Sep 2011, In: Journal of Ethnopharmacology. 137, 1, p. 921-925

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Medicinalplanter og abort: ny viden kan hjælpe afrikanske kvinder

    Jäger, A., Kristiansen, Uffe & Rasch, V., Dec 2011, In: Lægemiddelforskning. 2011, p. 23-25

    Research output: Contribution to journalJournal articleCommunication

  35. 2012
  36. Published

    Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?

    Hansen, S. L., Sterjev, Z., Werngreen, M., Simonsen, B. J., Knudsen, K. E., Nielsen, A. H., Pedersen, M. E., Badolo, L., Kristiansen, Uffe & Vestergaard, H. T., May 2012, In: European Journal of Pharmacology. 682, 1-3, p. 43-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 985515