A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands
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A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands. / Petersen, Trine P; Ritzén, Andreas; Ulven, Trond.
In: Organic Letters, Vol. 11, No. 22, 19.11.2009, p. 5134-5137.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A multistep continuous-flow system for rapid on-demand synthesis of receptor ligands
AU - Petersen, Trine P
AU - Ritzén, Andreas
AU - Ulven, Trond
PY - 2009/11/19
Y1 - 2009/11/19
N2 - A multistep continuous-flow system for synthesis of receptor ligands by assembly of three variable building blocks in a single unbroken flow is described. The sequence consists of three reactions and two scavenger steps, where a Cbz-protected diamine is reacted with an isocyanate, deprotected, and reacted further with an alkylating agent.
AB - A multistep continuous-flow system for synthesis of receptor ligands by assembly of three variable building blocks in a single unbroken flow is described. The sequence consists of three reactions and two scavenger steps, where a Cbz-protected diamine is reacted with an isocyanate, deprotected, and reacted further with an alkylating agent.
U2 - 10.1021/ol902101c
DO - 10.1021/ol902101c
M3 - Journal article
VL - 11
SP - 5134
EP - 5137
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 22
ER -
ID: 189160256