Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo. / Vermehren, C.; Johansen, P.B.; Hansen, Harald S.

In: Drug Metabolism and Disposition, Vol. 25, No. 9, 01.01.1997, p. 1083-1088.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Vermehren, C, Johansen, PB & Hansen, HS 1997, 'Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo', Drug Metabolism and Disposition, vol. 25, no. 9, pp. 1083-1088.

APA

Vermehren, C., Johansen, P. B., & Hansen, H. S. (1997). Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo. Drug Metabolism and Disposition, 25(9), 1083-1088.

Vancouver

Vermehren C, Johansen PB, Hansen HS. Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo. Drug Metabolism and Disposition. 1997 Jan 1;25(9):1083-1088.

Author

Vermehren, C. ; Johansen, P.B. ; Hansen, Harald S. / Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo. In: Drug Metabolism and Disposition. 1997 ; Vol. 25, No. 9. pp. 1083-1088.

Bibtex

@article{15221997e50341feb87cbd47dfc2d320,
title = "Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo",
abstract = "The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5% of the applied dose was found absorbed into the mucosa. The retained radioactivity left the tissue in ",
author = "C. Vermehren and P.B. Johansen and Hansen, {Harald S.}",
year = "1997",
month = jan,
day = "1",
language = "English",
volume = "25",
pages = "1083--1088",
journal = "Drug Metabolism and Disposition",
issn = "0090-9556",
publisher = "American Society for Pharmacology and Experimental Therapeutics",
number = "9",

}

RIS

TY - JOUR

T1 - Absorption and metabolism of the absorption enhancer didecanoylphosphatidylcholine in rabbit nasal epithelium in vivo

AU - Vermehren, C.

AU - Johansen, P.B.

AU - Hansen, Harald S.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5% of the applied dose was found absorbed into the mucosa. The retained radioactivity left the tissue in

AB - The absorption enhancer, didecanoylphosphatidylcholine (DDPC), improves the nasal absorption of human growth hormone in rabbits. We elucidated the uptake and the metabolism of 1,2-di[1-C]decanoyl-L-3-phosphatidylcholine and 1,2-didecanoyl-L-3-phosphatidyl[N-methyl-H]choline in rabbit nasal mucosa in vivo. One minute after nasal application of DDPC, 4.4-7.5% of the applied dose was found absorbed into the mucosa. The retained radioactivity left the tissue in

UR - http://www.scopus.com/inward/record.url?scp=0030821968&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0030821968

VL - 25

SP - 1083

EP - 1088

JO - Drug Metabolism and Disposition

JF - Drug Metabolism and Disposition

SN - 0090-9556

IS - 9

ER -

ID: 45562023