An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro
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An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro. / Larsen, Erik; Kharazmi, Arsalan; Christensen, Lars P.; Christensen, S. Brøgger.
In: Journal of Natural Products, Vol. 66, No. 7, 01.07.2003, p. 994-995.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - An antiinflammatory galactolipid from rose hip (Rosa canina) that inhibits chemotaxis of human peripheral blood neutrophils in vitro
AU - Larsen, Erik
AU - Kharazmi, Arsalan
AU - Christensen, Lars P.
AU - Christensen, S. Brøgger
PY - 2003/7/1
Y1 - 2003/7/1
N2 - The galactolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-β-D- galactopyranosyl glycerol (1) isolated from dried and milled fruits of Rosa canina by bioassay-guided fractionation is an antiinflammatory agent with inhibitory effects on chemotaxis of human peripheral blood neutrophils in vitro. The inhibition of cell migration is not related to toxicity. The presence of 1 in rose hips may explain the clinically observed antiinflammatory properties of rose hip herbal remedies.
AB - The galactolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-β-D- galactopyranosyl glycerol (1) isolated from dried and milled fruits of Rosa canina by bioassay-guided fractionation is an antiinflammatory agent with inhibitory effects on chemotaxis of human peripheral blood neutrophils in vitro. The inhibition of cell migration is not related to toxicity. The presence of 1 in rose hips may explain the clinically observed antiinflammatory properties of rose hip herbal remedies.
UR - http://www.scopus.com/inward/record.url?scp=0041342048&partnerID=8YFLogxK
U2 - 10.1021/np0300636
DO - 10.1021/np0300636
M3 - Journal article
C2 - 12880322
AN - SCOPUS:0041342048
VL - 66
SP - 994
EP - 995
JO - Journal of Natural Products
JF - Journal of Natural Products
SN - 0163-3864
IS - 7
ER -
ID: 232596664