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Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics. / Pedersen, Mie Fabricius; Wrobel, Tomasz Marcin; Märcher-Rørsted, Emil; Pedersen, Daniel Sejer; Møller, Thor Christian; Gabriele, Federica; Pedersen, Henrik; Matosiuk, Dariusz; Foster, Simon Richard; Bouvier, Michel; Bräuner-Osborne, Hans.
In:
Neuropharmacology, Vol. 166, 107718, 2020.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Pedersen, MF, Wrobel, TM
, Märcher-Rørsted, E, Pedersen, DS, Møller, TC, Gabriele, F, Pedersen, H, Matosiuk, D, Foster, SR, Bouvier, M
& Bräuner-Osborne, H 2020, '
Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics',
Neuropharmacology, vol. 166, 107718.
https://doi.org/10.1016/j.neuropharm.2019.107718APA
Pedersen, M. F., Wrobel, T. M.
, Märcher-Rørsted, E., Pedersen, D. S., Møller, T. C., Gabriele, F., Pedersen, H., Matosiuk, D., Foster, S. R., Bouvier, M.
, & Bräuner-Osborne, H. (2020).
Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.
Neuropharmacology,
166, [107718].
https://doi.org/10.1016/j.neuropharm.2019.107718Vancouver
Pedersen MF, Wrobel TM
, Märcher-Rørsted E, Pedersen DS, Møller TC, Gabriele F et al.
Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics.
Neuropharmacology. 2020;166. 107718.
https://doi.org/10.1016/j.neuropharm.2019.107718Author
Pedersen, Mie Fabricius ; Wrobel, Tomasz Marcin ; Märcher-Rørsted, Emil ; Pedersen, Daniel Sejer ; Møller, Thor Christian ; Gabriele, Federica ; Pedersen, Henrik ; Matosiuk, Dariusz ; Foster, Simon Richard ; Bouvier, Michel ; Bräuner-Osborne, Hans. / Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics. In: Neuropharmacology. 2020 ; Vol. 166.
Bibtex
@article{434a9df7d9c84af7ace5130300d650a3,
title = "Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics",
keywords = "Biased agonism, Binding kinetics, mu-opioid receptor, Oliceridine ((R)-TRV130)",
author = "Pedersen, {Mie Fabricius} and Wrobel, {Tomasz Marcin} and Emil M{\"a}rcher-R{\o}rsted and Pedersen, {Daniel Sejer} and M{\o}ller, {Thor Christian} and Federica Gabriele and Henrik Pedersen and Dariusz Matosiuk and Foster, {Simon Richard} and Michel Bouvier and Hans Br{\"a}uner-Osborne",
year = "2020",
doi = "10.1016/j.neuropharm.2019.107718",
language = "English",
volume = "166",
journal = "Neuropharmacology",
issn = "0028-3908",
publisher = "Pergamon Press",
}
RIS
TY - JOUR
T1 - Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics
AU - Pedersen, Mie Fabricius
AU - Wrobel, Tomasz Marcin
AU - Märcher-Rørsted, Emil
AU - Pedersen, Daniel Sejer
AU - Møller, Thor Christian
AU - Gabriele, Federica
AU - Pedersen, Henrik
AU - Matosiuk, Dariusz
AU - Foster, Simon Richard
AU - Bouvier, Michel
AU - Bräuner-Osborne, Hans
PY - 2020
Y1 - 2020
KW - Biased agonism
KW - Binding kinetics
KW - mu-opioid receptor
KW - Oliceridine ((R)-TRV130)
U2 - 10.1016/j.neuropharm.2019.107718
DO - 10.1016/j.neuropharm.2019.107718
M3 - Journal article
C2 - 31351108
VL - 166
JO - Neuropharmacology
JF - Neuropharmacology
SN - 0028-3908
M1 - 107718
ER -
