Clearing and Masking Agents in Pretargeting Strategies
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‘Pretargeting’ led to increased target-to-background ratios of nanomedicines in short timeframes. However, clearing or masking agents are needed to reach the full potential of pretargeted approaches. This review gives an overview of clearing and masking agents employed in pretargeting strategies in both preclinical and clinical settings and discusses how these agents work.
Original language | English |
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Article number | 497 |
Journal | Pharmaceuticals |
Volume | 16 |
Issue number | 4 |
Number of pages | 15 |
ISSN | 1424-8247 |
DOIs | |
Publication status | Published - 2023 |
Bibliographical note
Publisher Copyright:
© 2023 by the authors.
- bioorthogonal, clearing agents, masking agents, pretargeting, tetrazine ligation
Research areas
ID: 346407935