Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds
Research output: Contribution to journal › Journal article › Communication
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Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds. / Thanh Tung, Truong; Christensen, Søren Brøgger; Nielsen, John.
In: Chemistry - A European Journal, 25.10.2017.Research output: Contribution to journal › Journal article › Communication
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TY - JOUR
T1 - Cover picture: Difluoroacetic Acid as a New Reagent for Direct C−H Difluoromethylation of Heteroaromatic Compounds
AU - Thanh Tung, Truong
AU - Christensen, Søren Brøgger
AU - Nielsen, John
PY - 2017/10/25
Y1 - 2017/10/25
N2 - Direct C−H difluoromethylation of electron-deficient positions in nitrogen-containing heterocycles is attained by difluoromethyl radicals generated in-situ from difluoroacetic acid under silver-catalyzed oxidative decarboxylation. Control of the reaction temperature permits either mono- or disubstitution. More information can be found in the Communication by J. Nielsen et al. (DOI: 10.1002/chem.201704261).
AB - Direct C−H difluoromethylation of electron-deficient positions in nitrogen-containing heterocycles is attained by difluoromethyl radicals generated in-situ from difluoroacetic acid under silver-catalyzed oxidative decarboxylation. Control of the reaction temperature permits either mono- or disubstitution. More information can be found in the Communication by J. Nielsen et al. (DOI: 10.1002/chem.201704261).
M3 - Journal article
JO - Chemistry: A European Journal
JF - Chemistry: A European Journal
SN - 0947-6539
ER -
ID: 185005538