Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage. / Nørskov-Lauritsen, Leif; Jørgensen, Flemming S.; Jaroszewski, Jerzy W.

In: Carbohydrate Research, Vol. 123, No. 1, 11.11.1983, p. 1-11.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nørskov-Lauritsen, L, Jørgensen, FS & Jaroszewski, JW 1983, 'Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage', Carbohydrate Research, vol. 123, no. 1, pp. 1-11. https://doi.org/10.1016/0008-6215(83)88375-X

APA

Nørskov-Lauritsen, L., Jørgensen, F. S., & Jaroszewski, J. W. (1983). Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage. Carbohydrate Research, 123(1), 1-11. https://doi.org/10.1016/0008-6215(83)88375-X

Vancouver

Nørskov-Lauritsen L, Jørgensen FS, Jaroszewski JW. Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage. Carbohydrate Research. 1983 Nov 11;123(1):1-11. https://doi.org/10.1016/0008-6215(83)88375-X

Author

Nørskov-Lauritsen, Leif ; Jørgensen, Flemming S. ; Jaroszewski, Jerzy W. / Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage. In: Carbohydrate Research. 1983 ; Vol. 123, No. 1. pp. 1-11.

Bibtex

@article{d9ea9766479b4f72845127680e788826,
title = "Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage",
abstract = "The crystal structure of merosinigrin [(1′S,2′S)-1,2-S, O-(1-cyano-2-methyl-1,2-ethanediyl)-1-thio-β-d-glucopyranose], the long-known rearrangement product of allylglucosinolate, was determined by X-ray diffraction at 90 K, thereby revealing the geometry of an (ap,ap)-monothioacetal group. The crystals of merosinigrin, C10H15NO5S, are triclinic, P1, with cell dimensions a = 5.349(2), b = 6.664(3), c = 9.266(4) {\AA}, α = 85.91(3), β = 76.35(3), γ = 70.83(3)°, Z = 1. The structure was solved by direct methods and refined to R = 0.035 for 1789 independent reflections. For thioglycosides and other monothioacetals, the lengths of the central C-S and C-O bonds depend on the torsion angles about these bonds, consistent with a simple electron-delocalisation model. The central S-C-O valence angle in monothioacetals also Depends in a regular way on the torsion angles. Energy optimisation of methoxy(methylthio)methane, a thioglycoside model, by semiempirical molecular orbital calculations (MNDO) reproduced trends observed in the experimental data.",
author = "Leif N{\o}rskov-Lauritsen and J{\o}rgensen, {Flemming S.} and Jaroszewski, {Jerzy W.}",
year = "1983",
month = nov,
day = "11",
doi = "10.1016/0008-6215(83)88375-X",
language = "English",
volume = "123",
pages = "1--11",
journal = "Carbohydrate Research",
issn = "0008-6215",
publisher = "Pergamon Press",
number = "1",

}

RIS

TY - JOUR

T1 - Crystal structure of merosinigrin, an (ap,ap)-monothioacetal; structural properties of the thioglycosidic linkage

AU - Nørskov-Lauritsen, Leif

AU - Jørgensen, Flemming S.

AU - Jaroszewski, Jerzy W.

PY - 1983/11/11

Y1 - 1983/11/11

N2 - The crystal structure of merosinigrin [(1′S,2′S)-1,2-S, O-(1-cyano-2-methyl-1,2-ethanediyl)-1-thio-β-d-glucopyranose], the long-known rearrangement product of allylglucosinolate, was determined by X-ray diffraction at 90 K, thereby revealing the geometry of an (ap,ap)-monothioacetal group. The crystals of merosinigrin, C10H15NO5S, are triclinic, P1, with cell dimensions a = 5.349(2), b = 6.664(3), c = 9.266(4) Å, α = 85.91(3), β = 76.35(3), γ = 70.83(3)°, Z = 1. The structure was solved by direct methods and refined to R = 0.035 for 1789 independent reflections. For thioglycosides and other monothioacetals, the lengths of the central C-S and C-O bonds depend on the torsion angles about these bonds, consistent with a simple electron-delocalisation model. The central S-C-O valence angle in monothioacetals also Depends in a regular way on the torsion angles. Energy optimisation of methoxy(methylthio)methane, a thioglycoside model, by semiempirical molecular orbital calculations (MNDO) reproduced trends observed in the experimental data.

AB - The crystal structure of merosinigrin [(1′S,2′S)-1,2-S, O-(1-cyano-2-methyl-1,2-ethanediyl)-1-thio-β-d-glucopyranose], the long-known rearrangement product of allylglucosinolate, was determined by X-ray diffraction at 90 K, thereby revealing the geometry of an (ap,ap)-monothioacetal group. The crystals of merosinigrin, C10H15NO5S, are triclinic, P1, with cell dimensions a = 5.349(2), b = 6.664(3), c = 9.266(4) Å, α = 85.91(3), β = 76.35(3), γ = 70.83(3)°, Z = 1. The structure was solved by direct methods and refined to R = 0.035 for 1789 independent reflections. For thioglycosides and other monothioacetals, the lengths of the central C-S and C-O bonds depend on the torsion angles about these bonds, consistent with a simple electron-delocalisation model. The central S-C-O valence angle in monothioacetals also Depends in a regular way on the torsion angles. Energy optimisation of methoxy(methylthio)methane, a thioglycoside model, by semiempirical molecular orbital calculations (MNDO) reproduced trends observed in the experimental data.

UR - http://www.scopus.com/inward/record.url?scp=0342569549&partnerID=8YFLogxK

U2 - 10.1016/0008-6215(83)88375-X

DO - 10.1016/0008-6215(83)88375-X

M3 - Journal article

AN - SCOPUS:0342569549

VL - 123

SP - 1

EP - 11

JO - Carbohydrate Research

JF - Carbohydrate Research

SN - 0008-6215

IS - 1

ER -

ID: 218714272