Current radiosynthesis strategies for 5-HT2A receptor PET tracers

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Current radiosynthesis strategies for 5-HT2A receptor PET tracers. / Herth, Matthias M; Knudsen, Gitte M.

In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 58, No. 7, 15.06.2015, p. 265-73.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Herth, MM & Knudsen, GM 2015, 'Current radiosynthesis strategies for 5-HT2A receptor PET tracers', Journal of Labelled Compounds and Radiopharmaceuticals, vol. 58, no. 7, pp. 265-73. https://doi.org/10.1002/jlcr.3288

APA

Herth, M. M., & Knudsen, G. M. (2015). Current radiosynthesis strategies for 5-HT2A receptor PET tracers. Journal of Labelled Compounds and Radiopharmaceuticals, 58(7), 265-73. https://doi.org/10.1002/jlcr.3288

Vancouver

Herth MM, Knudsen GM. Current radiosynthesis strategies for 5-HT2A receptor PET tracers. Journal of Labelled Compounds and Radiopharmaceuticals. 2015 Jun 15;58(7):265-73. https://doi.org/10.1002/jlcr.3288

Author

Herth, Matthias M ; Knudsen, Gitte M. / Current radiosynthesis strategies for 5-HT2A receptor PET tracers. In: Journal of Labelled Compounds and Radiopharmaceuticals. 2015 ; Vol. 58, No. 7. pp. 265-73.

Bibtex

@article{4286c49b11f242c88fa78a7f7132c57e,
title = "Current radiosynthesis strategies for 5-HT2A receptor PET tracers",
abstract = "Serotonin 2A receptors have been implicated in various psychophysiological functions and disorders such as depression, Alzheimer's disease, or schizophrenia. Therefore, neuroimaging of this specific receptor is of significant clinical interest, and it is not surprising that many attempts have been made to develop a suitable 5-HT2A R positron emission tomography-tracer. In this review, we give an overview on the precursor, reference compound synthesis, and the preparation of promising 5-HT2A R radiopharmaceuticals applied in positron emission tomography. We also highlight possible learning outcomes that can be made from these tracer development processes.",
author = "Herth, {Matthias M} and Knudsen, {Gitte M}",
note = "Copyright {\textcopyright} 2015 John Wiley & Sons, Ltd.",
year = "2015",
month = jun,
day = "15",
doi = "10.1002/jlcr.3288",
language = "English",
volume = "58",
pages = "265--73",
journal = "Journal of Labelled Compounds and Radiopharmaceuticals",
issn = "0362-4803",
publisher = "JohnWiley & Sons Ltd",
number = "7",

}

RIS

TY - JOUR

T1 - Current radiosynthesis strategies for 5-HT2A receptor PET tracers

AU - Herth, Matthias M

AU - Knudsen, Gitte M

N1 - Copyright © 2015 John Wiley & Sons, Ltd.

PY - 2015/6/15

Y1 - 2015/6/15

N2 - Serotonin 2A receptors have been implicated in various psychophysiological functions and disorders such as depression, Alzheimer's disease, or schizophrenia. Therefore, neuroimaging of this specific receptor is of significant clinical interest, and it is not surprising that many attempts have been made to develop a suitable 5-HT2A R positron emission tomography-tracer. In this review, we give an overview on the precursor, reference compound synthesis, and the preparation of promising 5-HT2A R radiopharmaceuticals applied in positron emission tomography. We also highlight possible learning outcomes that can be made from these tracer development processes.

AB - Serotonin 2A receptors have been implicated in various psychophysiological functions and disorders such as depression, Alzheimer's disease, or schizophrenia. Therefore, neuroimaging of this specific receptor is of significant clinical interest, and it is not surprising that many attempts have been made to develop a suitable 5-HT2A R positron emission tomography-tracer. In this review, we give an overview on the precursor, reference compound synthesis, and the preparation of promising 5-HT2A R radiopharmaceuticals applied in positron emission tomography. We also highlight possible learning outcomes that can be made from these tracer development processes.

U2 - 10.1002/jlcr.3288

DO - 10.1002/jlcr.3288

M3 - Journal article

C2 - 25997728

VL - 58

SP - 265

EP - 273

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

SN - 0362-4803

IS - 7

ER -

ID: 151556875