Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours. / Wang, Jinmei; Wu, Yazhen; Heegaard, Steffen; Kolko, Miriam.

In: Acta Ophthamologica (Online), 11.2011, p. 681-685.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Wang, J, Wu, Y, Heegaard, S & Kolko, M 2011, 'Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours', Acta Ophthamologica (Online), pp. 681-685.

APA

Wang, J., Wu, Y., Heegaard, S., & Kolko, M. (2011). Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours. Acta Ophthamologica (Online), 681-685.

Vancouver

Wang J, Wu Y, Heegaard S, Kolko M. Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours. Acta Ophthamologica (Online). 2011 Nov;681-685.

Author

Wang, Jinmei ; Wu, Yazhen ; Heegaard, Steffen ; Kolko, Miriam. / Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours. In: Acta Ophthamologica (Online). 2011 ; pp. 681-685.

Bibtex

@article{27b455c088cc11df928f000ea68e967b,
title = "Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours",
abstract = "Purpose: Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. The purpose of the present study is to investigate COX-2 expression in the normal human eye and the expression pattern in selected eye tumours involving COX-2 expressing cells. Methods: Immunohistochemical staining using antibodies against COX-2 was performed on paraffin sections of normal human eyes and selected eye tumours arising from cells expressing COX-2. Results: Cyclooxygenase-2 expression was found in various structures of the normal eye. Abundant expression was seen in the cornea, iris, ciliary body and retina. The COX-2 expression was less in tumours deriving from the ciliary epithelium and also in retinoblastoma. Conclusion: Cyclooxygenase-2 is constitutively expressed in normal human eyes. The expression of COX-2 is much lower in selected eye tumours involving COX-2 expressing cells.",
author = "Jinmei Wang and Yazhen Wu and Steffen Heegaard and Miriam Kolko",
year = "2011",
month = nov,
language = "English",
pages = "681--685",
journal = "Acta Ophthalmologica",
issn = "1755-375X",
publisher = "Wiley-Blackwell",

}

RIS

TY - JOUR

T1 - Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours

AU - Wang, Jinmei

AU - Wu, Yazhen

AU - Heegaard, Steffen

AU - Kolko, Miriam

PY - 2011/11

Y1 - 2011/11

N2 - Purpose: Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. The purpose of the present study is to investigate COX-2 expression in the normal human eye and the expression pattern in selected eye tumours involving COX-2 expressing cells. Methods: Immunohistochemical staining using antibodies against COX-2 was performed on paraffin sections of normal human eyes and selected eye tumours arising from cells expressing COX-2. Results: Cyclooxygenase-2 expression was found in various structures of the normal eye. Abundant expression was seen in the cornea, iris, ciliary body and retina. The COX-2 expression was less in tumours deriving from the ciliary epithelium and also in retinoblastoma. Conclusion: Cyclooxygenase-2 is constitutively expressed in normal human eyes. The expression of COX-2 is much lower in selected eye tumours involving COX-2 expressing cells.

AB - Purpose: Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. The purpose of the present study is to investigate COX-2 expression in the normal human eye and the expression pattern in selected eye tumours involving COX-2 expressing cells. Methods: Immunohistochemical staining using antibodies against COX-2 was performed on paraffin sections of normal human eyes and selected eye tumours arising from cells expressing COX-2. Results: Cyclooxygenase-2 expression was found in various structures of the normal eye. Abundant expression was seen in the cornea, iris, ciliary body and retina. The COX-2 expression was less in tumours deriving from the ciliary epithelium and also in retinoblastoma. Conclusion: Cyclooxygenase-2 is constitutively expressed in normal human eyes. The expression of COX-2 is much lower in selected eye tumours involving COX-2 expressing cells.

M3 - Journal article

C2 - 19925514

SP - 681

EP - 685

JO - Acta Ophthalmologica

JF - Acta Ophthalmologica

SN - 1755-375X

ER -

ID: 20649048