Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217

Research output: Contribution to conference › Poster › Research › peer-review

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Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217. / Nielsen, John.

2018. Poster session presented at 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

Research output: Contribution to conference › Poster › Research › peer-review

Harvard

Nielsen, J 2018, 'Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217', 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States, 19/08/2018 - 23/08/2018. <https://www.acs.org/content/dam/acsorg/meetings/national-meetings/fall-2018/fall-2018-program-book.pdf>

APA

Nielsen, J. (2018). Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217. Poster session presented at 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States. https://www.acs.org/content/dam/acsorg/meetings/national-meetings/fall-2018/fall-2018-program-book.pdf

Vancouver

Nielsen J. Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217. 2018. Poster session presented at 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.

Author

Nielsen, John. / Discovering drugs from plants or drugs in plants? Conference Abstract MEDI 217. Poster session presented at 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond, United States.1 p.

Bibtex

@conference{ba332fac7d6242a493243e2d9506a7ab,
title = "Discovering drugs from plants or drugs in plants?: Conference Abstract MEDI 217",
abstract = "A phytochemical investigation of Seidlitzia rosmarinus collected along the shoreline of the Gulf of Aqaba in the remote southern desert region of the Sinai peninsula has revealed the presence of the registered drug metformin. However, analysis of the 14C content revealed the drug to be an anthropogenic contaminant. Consequently, natural product researchers should be aware that compounds isolated from plants might originate from environmental contamination rather than biosynthesis. The new natural product N-(4-hydroxyphenylethyl)-alpha-chloroferuloylamide was isolated as a mixture of the E and Z isomers along with a number of other well-established secondary metabolites.During this presentation, the importance of natural products in drug discovery will be underlined with important examples from the history of human medicines and so recent accomplishments. However, landmark examples of drugs leaking into the environment and eventually being {"}discovered{"} is also provided and critically reviewed.",
author = "John Nielsen",
note = "Conference Abstract MEDI 217; 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond ; Conference date: 19-08-2018 Through 23-08-2018",
year = "2018",
month = aug,
day = "19",
language = "English",

}

RIS

TY - CONF

T1 - Discovering drugs from plants or drugs in plants?

T2 - 256th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nanoscience, Nanotechnology and Beyond

AU - Nielsen, John

N1 - Conference code: 189

PY - 2018/8/19

Y1 - 2018/8/19

N2 - A phytochemical investigation of Seidlitzia rosmarinus collected along the shoreline of the Gulf of Aqaba in the remote southern desert region of the Sinai peninsula has revealed the presence of the registered drug metformin. However, analysis of the 14C content revealed the drug to be an anthropogenic contaminant. Consequently, natural product researchers should be aware that compounds isolated from plants might originate from environmental contamination rather than biosynthesis. The new natural product N-(4-hydroxyphenylethyl)-alpha-chloroferuloylamide was isolated as a mixture of the E and Z isomers along with a number of other well-established secondary metabolites.During this presentation, the importance of natural products in drug discovery will be underlined with important examples from the history of human medicines and so recent accomplishments. However, landmark examples of drugs leaking into the environment and eventually being "discovered" is also provided and critically reviewed.

AB - A phytochemical investigation of Seidlitzia rosmarinus collected along the shoreline of the Gulf of Aqaba in the remote southern desert region of the Sinai peninsula has revealed the presence of the registered drug metformin. However, analysis of the 14C content revealed the drug to be an anthropogenic contaminant. Consequently, natural product researchers should be aware that compounds isolated from plants might originate from environmental contamination rather than biosynthesis. The new natural product N-(4-hydroxyphenylethyl)-alpha-chloroferuloylamide was isolated as a mixture of the E and Z isomers along with a number of other well-established secondary metabolites.During this presentation, the importance of natural products in drug discovery will be underlined with important examples from the history of human medicines and so recent accomplishments. However, landmark examples of drugs leaking into the environment and eventually being "discovered" is also provided and critically reviewed.

M3 - Poster

Y2 - 19 August 2018 through 23 August 2018

ER -

ID: 209707483