Effect of sex in the MRMT-1 model of cancer-induced bone pain

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Effect of sex in the MRMT-1 model of cancer-induced bone pain. / Falk, Sarah; Al-Dihaissy, Tamara; Mezzanotte, Laura; Heegaard, Anne-Marie.

In: F1000Research, Vol. 4, No. 445, 445, 2015, p. 1-18.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Falk, S, Al-Dihaissy, T, Mezzanotte, L & Heegaard, A-M 2015, 'Effect of sex in the MRMT-1 model of cancer-induced bone pain', F1000Research, vol. 4, no. 445, 445, pp. 1-18. https://doi.org/10.12688/f1000research.6827.3

APA

Falk, S., Al-Dihaissy, T., Mezzanotte, L., & Heegaard, A-M. (2015). Effect of sex in the MRMT-1 model of cancer-induced bone pain. F1000Research, 4(445), 1-18. [445]. https://doi.org/10.12688/f1000research.6827.3

Vancouver

Falk S, Al-Dihaissy T, Mezzanotte L, Heegaard A-M. Effect of sex in the MRMT-1 model of cancer-induced bone pain. F1000Research. 2015;4(445):1-18. 445. https://doi.org/10.12688/f1000research.6827.3

Author

Falk, Sarah ; Al-Dihaissy, Tamara ; Mezzanotte, Laura ; Heegaard, Anne-Marie. / Effect of sex in the MRMT-1 model of cancer-induced bone pain. In: F1000Research. 2015 ; Vol. 4, No. 445. pp. 1-18.

Bibtex

@article{ba0fa0ed15c1481ebb83e526c0c2b2b1,
title = "Effect of sex in the MRMT-1 model of cancer-induced bone pain",
abstract = "An overwhelming amount of evidence demonstrates sex-induced variation in pain processing, and has thus increased the focus on sex as an essential parameter for optimization of in vivo models in pain research. Mammary cancer cells are often used to model metastatic bone pain in vivo, and are commonly used in both males and females. Here we demonstrate that compared to male rats, female rats have an increased capacity for recovery following inoculation of MRMT-1 mammary cells, thus potentially causing a sex-dependent bias in interpretation of the data.",
author = "Sarah Falk and Tamara Al-Dihaissy and Laura Mezzanotte and Anne-Marie Heegaard",
note = "CURIS 2015 NEXS 426",
year = "2015",
doi = "10.12688/f1000research.6827.3",
language = "English",
volume = "4",
pages = "1--18",
journal = "F1000Research",
issn = "2046-1402",
publisher = "F1000Research",
number = "445",

}

RIS

TY - JOUR

T1 - Effect of sex in the MRMT-1 model of cancer-induced bone pain

AU - Falk, Sarah

AU - Al-Dihaissy, Tamara

AU - Mezzanotte, Laura

AU - Heegaard, Anne-Marie

N1 - CURIS 2015 NEXS 426

PY - 2015

Y1 - 2015

N2 - An overwhelming amount of evidence demonstrates sex-induced variation in pain processing, and has thus increased the focus on sex as an essential parameter for optimization of in vivo models in pain research. Mammary cancer cells are often used to model metastatic bone pain in vivo, and are commonly used in both males and females. Here we demonstrate that compared to male rats, female rats have an increased capacity for recovery following inoculation of MRMT-1 mammary cells, thus potentially causing a sex-dependent bias in interpretation of the data.

AB - An overwhelming amount of evidence demonstrates sex-induced variation in pain processing, and has thus increased the focus on sex as an essential parameter for optimization of in vivo models in pain research. Mammary cancer cells are often used to model metastatic bone pain in vivo, and are commonly used in both males and females. Here we demonstrate that compared to male rats, female rats have an increased capacity for recovery following inoculation of MRMT-1 mammary cells, thus potentially causing a sex-dependent bias in interpretation of the data.

U2 - 10.12688/f1000research.6827.3

DO - 10.12688/f1000research.6827.3

M3 - Journal article

C2 - 26834983

VL - 4

SP - 1

EP - 18

JO - F1000Research

JF - F1000Research

SN - 2046-1402

IS - 445

M1 - 445

ER -

ID: 144411400